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Plasma cell balanitis: clinicopathologic study of 112 cases and treatment modalities.
J Cutan Med Surg. 2006 Jan-Feb; 10(1):11-5.JC

Abstract

BACKGROUND

Plasma cell balanitis or Zoon's balanitis is an idiopathic benign condition of the genitalia that mostly presents as a solitary, persistent plaque on the glans primarily in uncircumcised, middle-aged to older men.

METHODS

One hundred twelve patients with a clinical diagnosis of plasma cell balanitis were studied between January 1985 and April 2003.

RESULTS

The age of the patients ranged from 24 to 70 years. The majority of patients had symptoms for more than 12 months. Lesions involved the prepuce and glans in the majority of patients (66; 58.92%), the prepuce only in 26 patients (23.21%), and the glans only in 20 patients (17.85%). Tissue for histopathology was available in 96 patients. Histologically, epidermal edema, a dense upper dermal band of chronic inflammatory cells, including many plasma cells, dilated capillaries, extravasated red blood cells, and hemosiderin deposition, was seen. In most, cases, plasma cell balanitis was successfully treated by circumcision.

CONCLUSIONS

This report describes our experience with plasma cell balanitis and reviews its clinical and histopathologic aspects. The treatment modalities are also reviewed, and the importance of circumcision as the treatment of choice is emphasized.

Authors+Show Affiliations

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. kumarbhushan@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17241566

Citation

Kumar, Bhushan, et al. "Plasma Cell Balanitis: Clinicopathologic Study of 112 Cases and Treatment Modalities." Journal of Cutaneous Medicine and Surgery, vol. 10, no. 1, 2006, pp. 11-5.
Kumar B, Narang T, Dass Radotra B, et al. Plasma cell balanitis: clinicopathologic study of 112 cases and treatment modalities. J Cutan Med Surg. 2006;10(1):11-5.
Kumar, B., Narang, T., Dass Radotra, B., & Gupta, S. (2006). Plasma cell balanitis: clinicopathologic study of 112 cases and treatment modalities. Journal of Cutaneous Medicine and Surgery, 10(1), 11-5.
Kumar B, et al. Plasma Cell Balanitis: Clinicopathologic Study of 112 Cases and Treatment Modalities. J Cutan Med Surg. 2006 Jan-Feb;10(1):11-5. PubMed PMID: 17241566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasma cell balanitis: clinicopathologic study of 112 cases and treatment modalities. AU - Kumar,Bhushan, AU - Narang,Tarun, AU - Dass Radotra,Bishan, AU - Gupta,Somesh, PY - 2007/1/24/pubmed PY - 2007/11/6/medline PY - 2007/1/24/entrez SP - 11 EP - 5 JF - Journal of cutaneous medicine and surgery JO - J Cutan Med Surg VL - 10 IS - 1 N2 - BACKGROUND: Plasma cell balanitis or Zoon's balanitis is an idiopathic benign condition of the genitalia that mostly presents as a solitary, persistent plaque on the glans primarily in uncircumcised, middle-aged to older men. METHODS: One hundred twelve patients with a clinical diagnosis of plasma cell balanitis were studied between January 1985 and April 2003. RESULTS: The age of the patients ranged from 24 to 70 years. The majority of patients had symptoms for more than 12 months. Lesions involved the prepuce and glans in the majority of patients (66; 58.92%), the prepuce only in 26 patients (23.21%), and the glans only in 20 patients (17.85%). Tissue for histopathology was available in 96 patients. Histologically, epidermal edema, a dense upper dermal band of chronic inflammatory cells, including many plasma cells, dilated capillaries, extravasated red blood cells, and hemosiderin deposition, was seen. In most, cases, plasma cell balanitis was successfully treated by circumcision. CONCLUSIONS: This report describes our experience with plasma cell balanitis and reviews its clinical and histopathologic aspects. The treatment modalities are also reviewed, and the importance of circumcision as the treatment of choice is emphasized. SN - 1203-4754 UR - https://www.unboundmedicine.com/medline/citation/17241566/Plasma_cell_balanitis:_clinicopathologic_study_of_112_cases_and_treatment_modalities_ L2 - https://journals.sagepub.com/doi/10.1007/7140.2006.00008?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -