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Clinical usefulness of probiotics in inflammatory bowel diseases.
J Physiol Pharmacol. 2006 Nov; 57 Suppl 9:23-33.JP

Abstract

Probiotics are live nonpathogenic bacteria or bacterial components that may be helpful in the prevention and treatment of acute diarrhoea in adults and children and have some effects on the course of inflammatory bowel diseases (IBD). Many experimental and clinical studies suggest that intestinal bacterial flora plays an important role in the pathogenesis of IBD, and manipulation of the luminal contents with antibiotics or probiotics represents a potentially effective therapeutic option. The beneficial effect of probiotics was demonstrated mainly in the prevention and treatment of pouchitis and in maintaining remission of mild to moderate ulcerative colitis. Probiotics seems to be less effective in patients with Crohn's disease. Randomized clinical trials are still required to further define the role of probiotics as preventive and therapeutic agents. This review summarizes the current data about probiotics in IBD.

Authors+Show Affiliations

Department of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, Krakow, Poland. tmach@su.krakow.pl

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17242485

Citation

Mach, T. "Clinical Usefulness of Probiotics in Inflammatory Bowel Diseases." Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society, vol. 57 Suppl 9, 2006, pp. 23-33.
Mach T. Clinical usefulness of probiotics in inflammatory bowel diseases. J Physiol Pharmacol. 2006;57 Suppl 9:23-33.
Mach, T. (2006). Clinical usefulness of probiotics in inflammatory bowel diseases. Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society, 57 Suppl 9, 23-33.
Mach T. Clinical Usefulness of Probiotics in Inflammatory Bowel Diseases. J Physiol Pharmacol. 2006;57 Suppl 9:23-33. PubMed PMID: 17242485.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical usefulness of probiotics in inflammatory bowel diseases. A1 - Mach,T, PY - 2006/10/30/received PY - 2006/11/10/accepted PY - 2007/1/24/pubmed PY - 2007/12/20/medline PY - 2007/1/24/entrez SP - 23 EP - 33 JF - Journal of physiology and pharmacology : an official journal of the Polish Physiological Society JO - J. Physiol. Pharmacol. VL - 57 Suppl 9 N2 - Probiotics are live nonpathogenic bacteria or bacterial components that may be helpful in the prevention and treatment of acute diarrhoea in adults and children and have some effects on the course of inflammatory bowel diseases (IBD). Many experimental and clinical studies suggest that intestinal bacterial flora plays an important role in the pathogenesis of IBD, and manipulation of the luminal contents with antibiotics or probiotics represents a potentially effective therapeutic option. The beneficial effect of probiotics was demonstrated mainly in the prevention and treatment of pouchitis and in maintaining remission of mild to moderate ulcerative colitis. Probiotics seems to be less effective in patients with Crohn's disease. Randomized clinical trials are still required to further define the role of probiotics as preventive and therapeutic agents. This review summarizes the current data about probiotics in IBD. SN - 1899-1505 UR - https://www.unboundmedicine.com/medline/citation/17242485/Clinical_usefulness_of_probiotics_in_inflammatory_bowel_diseases_ DB - PRIME DP - Unbound Medicine ER -