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Embolization combined with endoscopic variceal ligation for the treatment of esophagogastric variceal bleeding in patients with cirrhosis.
Chin Med J (Engl). 2007 Jan 05; 120(1):36-40.CM

Abstract

BACKGROUND

Esophagogastric variceal bleeding caused by cirrhosis is a kind of emergent condition in the clinic. This study was conducted to explore the therapeutic effect and superiority of embolization of gastric fundus varices combined with endoscopic variceal ligation (EVL) of esophageal varices for the treatment of patients with esophagogastric variceal bleeding caused by cirrhosis.

METHODS

Totally 172 patients were diagnosed by endoscopic examination within 24 hours of hospitalization with active gastric fundus variceal bleeding and grade II above esophageal varices caused by cirrhosis. Other causes leading to upper digestive tract bleeding were excluded. Patients were randomly divided into a control group (n = 82) and a therapy group (n = 90) following a random number table method. For the former, embolization for gastric fundus varices was performed, then an EVL for esophageal varices was performed 2 months later. For the therapy group, embolization for gastric fundus varices and EVL for esophageal varices were performed at the same time.

RESULTS

The rate of emergency hemostasis in the therapy group was 100.0%, higher than that in the control group (87.8%, P < 0.05). The rate of early rebleeding in the therapy group was 6.7% while the rate in the control group was 23.6% (P < 0.05). No complications related to treatment occurred in both groups.

CONCLUSION

Embolization for gastric fundus varices combined with EVL for esophageal varices is a safe and effective method for the treatment of patients with esophagogastric variceal bleeding caused by cirrhosis.

Authors+Show Affiliations

Department of Gastroenterology, Yuhuangding Hospital, Medical College of Qingdao University, Yantai 264000, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

17254485

Citation

Huang, Liu-Ye, et al. "Embolization Combined With Endoscopic Variceal Ligation for the Treatment of Esophagogastric Variceal Bleeding in Patients With Cirrhosis." Chinese Medical Journal, vol. 120, no. 1, 2007, pp. 36-40.
Huang LY, Cui J, Wu CR, et al. Embolization combined with endoscopic variceal ligation for the treatment of esophagogastric variceal bleeding in patients with cirrhosis. Chin Med J. 2007;120(1):36-40.
Huang, L. Y., Cui, J., Wu, C. R., & Liu, Y. X. (2007). Embolization combined with endoscopic variceal ligation for the treatment of esophagogastric variceal bleeding in patients with cirrhosis. Chinese Medical Journal, 120(1), 36-40.
Huang LY, et al. Embolization Combined With Endoscopic Variceal Ligation for the Treatment of Esophagogastric Variceal Bleeding in Patients With Cirrhosis. Chin Med J. 2007 Jan 5;120(1):36-40. PubMed PMID: 17254485.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Embolization combined with endoscopic variceal ligation for the treatment of esophagogastric variceal bleeding in patients with cirrhosis. AU - Huang,Liu-Ye, AU - Cui,Jun, AU - Wu,Cheng-Rong, AU - Liu,Yun-Xiang, PY - 2007/1/27/pubmed PY - 2007/2/21/medline PY - 2007/1/27/entrez SP - 36 EP - 40 JF - Chinese medical journal JO - Chin. Med. J. VL - 120 IS - 1 N2 - BACKGROUND: Esophagogastric variceal bleeding caused by cirrhosis is a kind of emergent condition in the clinic. This study was conducted to explore the therapeutic effect and superiority of embolization of gastric fundus varices combined with endoscopic variceal ligation (EVL) of esophageal varices for the treatment of patients with esophagogastric variceal bleeding caused by cirrhosis. METHODS: Totally 172 patients were diagnosed by endoscopic examination within 24 hours of hospitalization with active gastric fundus variceal bleeding and grade II above esophageal varices caused by cirrhosis. Other causes leading to upper digestive tract bleeding were excluded. Patients were randomly divided into a control group (n = 82) and a therapy group (n = 90) following a random number table method. For the former, embolization for gastric fundus varices was performed, then an EVL for esophageal varices was performed 2 months later. For the therapy group, embolization for gastric fundus varices and EVL for esophageal varices were performed at the same time. RESULTS: The rate of emergency hemostasis in the therapy group was 100.0%, higher than that in the control group (87.8%, P < 0.05). The rate of early rebleeding in the therapy group was 6.7% while the rate in the control group was 23.6% (P < 0.05). No complications related to treatment occurred in both groups. CONCLUSION: Embolization for gastric fundus varices combined with EVL for esophageal varices is a safe and effective method for the treatment of patients with esophagogastric variceal bleeding caused by cirrhosis. SN - 0366-6999 UR - https://www.unboundmedicine.com/medline/citation/17254485/Embolization_combined_with_endoscopic_variceal_ligation_for_the_treatment_of_esophagogastric_variceal_bleeding_in_patients_with_cirrhosis_ L2 - http://Insights.ovid.com/pubmed?pmid=17254485 DB - PRIME DP - Unbound Medicine ER -