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Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone.
J Antibiot (Tokyo). 2006 Nov; 59(11):704-9.JA

Abstract

Three polyketides containing a pyrone ring, neofusapyrone, fusapyrone, and deoxyfusapyrone, were isolated from the marine-derived fungus Fusarium sp. FH-146. Their structures were determined by extensive ID- and 2D-NMR and MS spectral analyses. Fusapyrone and deoxyfusapyrone were originally reported as a-pyrone derivatives; however, the revised structures indicate that they are gamma-pyrone derivatives. These three compounds exhibited antimicrobial activities.

Authors+Show Affiliations

Hiramatsu F
Department of Bioresource Engineering, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan.
Miyajima T
No affiliation info available
Murayama T
No affiliation info available
Takahashi K
No affiliation info available
Koseki T
No affiliation info available
Shiono Y
No affiliation info available

MeSH

Anti-Infective AgentsAspergillusCandida albicansFermentationFusariumMicrobial Sensitivity TestsNuclear Magnetic Resonance, BiomolecularOptical RotationPseudomonas aeruginosaPyronesSpectrometry, Mass, Fast Atom BombardmentSpectrophotometry, InfraredSpectrophotometry, UltravioletStaphylococcus aureus

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17256469

Citation

Hiramatsu, Fuminori, et al. "Isolation and Structure Elucidation of Neofusapyrone From a Marine-derived Fusarium Species, and Structural Revision of Fusapyrone and Deoxyfusapyrone." The Journal of Antibiotics, vol. 59, no. 11, 2006, pp. 704-9.
Hiramatsu F, Miyajima T, Murayama T, et al. Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone. J Antibiot (Tokyo). 2006;59(11):704-9.
Hiramatsu, F., Miyajima, T., Murayama, T., Takahashi, K., Koseki, T., & Shiono, Y. (2006). Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone. The Journal of Antibiotics, 59(11), 704-9.
Hiramatsu F, et al. Isolation and Structure Elucidation of Neofusapyrone From a Marine-derived Fusarium Species, and Structural Revision of Fusapyrone and Deoxyfusapyrone. J Antibiot (Tokyo). 2006;59(11):704-9. PubMed PMID: 17256469.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone. AU - Hiramatsu,Fuminori, AU - Miyajima,Takeshi, AU - Murayama,Tetsuya, AU - Takahashi,Koetsu, AU - Koseki,Takuya, AU - Shiono,Yoshihito, PY - 2007/1/30/pubmed PY - 2007/2/23/medline PY - 2007/1/30/entrez SP - 704 EP - 9 JF - The Journal of antibiotics JO - J Antibiot (Tokyo) VL - 59 IS - 11 N2 - Three polyketides containing a pyrone ring, neofusapyrone, fusapyrone, and deoxyfusapyrone, were isolated from the marine-derived fungus Fusarium sp. FH-146. Their structures were determined by extensive ID- and 2D-NMR and MS spectral analyses. Fusapyrone and deoxyfusapyrone were originally reported as a-pyrone derivatives; however, the revised structures indicate that they are gamma-pyrone derivatives. These three compounds exhibited antimicrobial activities. SN - 0021-8820 UR - https://www.unboundmedicine.com/medline/citation/17256469/Isolation_and_structure_elucidation_of_neofusapyrone_from_a_marine_derived_Fusarium_species_and_structural_revision_of_fusapyrone_and_deoxyfusapyrone_ L2 - https://doi.org/10.1038/ja.2006.94 DB - PRIME DP - Unbound Medicine ER -