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[A new indole alkaloid glycoside from stems of Nauclea officinalis].
Yao Xue Xue Bao. 2006 Nov; 41(11):1064-7.YX

Abstract

AIM

To investigate the chemical constituents of water-soluble part of stem of Nauclea officinalis.

METHODS

The compounds were isolated and purified by resins, silica gel, and Sephadex LH20 column chromatography repeatedly, and their structures were identified by spectral analysis.

RESULTS

Seven compounds were isolated and identified as: naucleamide A-10-O-beta-D-glucopyranoside (I), 5-beta-carboxystrictosidin (II), sweroside (III), loganin (IV), 3,4-dimethoxyphenyl-beta-D-glucopyranoside (V), 3, 4, 5-trimethoxyphenyl-beta-D-glucopyranoside (VI), 2-phenethylrutinoside (VII).

CONCLUSION

Compound I is a new indole alkaloid glucoside, compounds I-VII were isolated from this plant for the first time.

Authors+Show Affiliations

Xuan WD
School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Chen HS
No affiliation info available
Bian J
No affiliation info available

MeSH

CarbolinesGlucosidesGlycosidesIndole AlkaloidsIridoid GlucosidesIridoidsMolecular ConformationMolecular StructurePlant StemsPlants, MedicinalRubiaceae

Pub Type(s)

Journal Article

Language

chi

PubMed ID

17262948

Citation

Xuan, Wei-dong, et al. "[A New Indole Alkaloid Glycoside From Stems of Nauclea Officinalis]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 41, no. 11, 2006, pp. 1064-7.
Xuan WD, Chen HS, Bian J. [A new indole alkaloid glycoside from stems of Nauclea officinalis]. Yao Xue Xue Bao. 2006;41(11):1064-7.
Xuan, W. D., Chen, H. S., & Bian, J. (2006). [A new indole alkaloid glycoside from stems of Nauclea officinalis]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 41(11), 1064-7.
Xuan WD, Chen HS, Bian J. [A New Indole Alkaloid Glycoside From Stems of Nauclea Officinalis]. Yao Xue Xue Bao. 2006;41(11):1064-7. PubMed PMID: 17262948.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A new indole alkaloid glycoside from stems of Nauclea officinalis]. AU - Xuan,Wei-dong, AU - Chen,Hai-sheng, AU - Bian,Jun, PY - 2007/2/1/pubmed PY - 2008/5/10/medline PY - 2007/2/1/entrez SP - 1064 EP - 7 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 41 IS - 11 N2 - AIM: To investigate the chemical constituents of water-soluble part of stem of Nauclea officinalis. METHODS: The compounds were isolated and purified by resins, silica gel, and Sephadex LH20 column chromatography repeatedly, and their structures were identified by spectral analysis. RESULTS: Seven compounds were isolated and identified as: naucleamide A-10-O-beta-D-glucopyranoside (I), 5-beta-carboxystrictosidin (II), sweroside (III), loganin (IV), 3,4-dimethoxyphenyl-beta-D-glucopyranoside (V), 3, 4, 5-trimethoxyphenyl-beta-D-glucopyranoside (VI), 2-phenethylrutinoside (VII). CONCLUSION: Compound I is a new indole alkaloid glucoside, compounds I-VII were isolated from this plant for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/17262948/[A_new_indole_alkaloid_glycoside_from_stems_of_Nauclea_officinalis]_ DB - PRIME DP - Unbound Medicine ER -