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Children's vaccines do not induce cross reactivity against SARS-CoV.
J Clin Pathol. 2007 Feb; 60(2):208-11.JC

Abstract

In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.

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Authors+Show Affiliations

Yu Y
State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, China.
Jin H
No affiliation info available
Chen Z
No affiliation info available
Yu QL
No affiliation info available
Ma YJ
No affiliation info available
Sun XL
No affiliation info available
Wang B
No affiliation info available

MeSH

AnimalsAntibodies, ViralChildChild, PreschoolCross ReactionsEnzyme-Linked Immunosorbent AssayHumansImmune SeraImmunizationInfantMiceMice, Inbred C57BLSARS VirusSevere Acute Respiratory SyndromeT-LymphocytesVaccines

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17264247

Citation

Yu, Yang, et al. "Children's Vaccines Do Not Induce Cross Reactivity Against SARS-CoV." Journal of Clinical Pathology, vol. 60, no. 2, 2007, pp. 208-11.
Yu Y, Jin H, Chen Z, et al. Children's vaccines do not induce cross reactivity against SARS-CoV. J Clin Pathol. 2007;60(2):208-11.
Yu, Y., Jin, H., Chen, Z., Yu, Q. L., Ma, Y. J., Sun, X. L., & Wang, B. (2007). Children's vaccines do not induce cross reactivity against SARS-CoV. Journal of Clinical Pathology, 60(2), 208-11.
Yu Y, et al. Children's Vaccines Do Not Induce Cross Reactivity Against SARS-CoV. J Clin Pathol. 2007;60(2):208-11. PubMed PMID: 17264247.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Children's vaccines do not induce cross reactivity against SARS-CoV. AU - Yu,Yang, AU - Jin,Huali, AU - Chen,Ze, AU - Yu,Qingling L, AU - Ma,Yijie J, AU - Sun,Xiaolin L, AU - Wang,Bin, PY - 2007/2/1/pubmed PY - 2007/3/3/medline PY - 2007/2/1/entrez SP - 208 EP - 11 JF - Journal of clinical pathology JO - J Clin Pathol VL - 60 IS - 2 N2 - In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors. SN - 0021-9746 UR - https://www.unboundmedicine.com/medline/citation/17264247/full_citation DB - PRIME DP - Unbound Medicine ER -