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Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone.
Obstet Gynecol. 2007 Feb; 109(2 Pt2):528-30.OG

Abstract

BACKGROUND

We report a case of diffuse uterine leiomyomatosis in pregnancy complicated by uterine rupture and dissemination to the bone.

CASE

A 35-year-old nulliparous woman with a history of uterine leiomyoma presented at term with fetal demise. Failed induction of labor and hemodynamic instability due to uterine rupture resulted in a cesarean hysterectomy. A free-air series performed postoperatively to confirm paralytic ileus revealed multiple lytic bone lesions. The diagnosis of diffuse uterine leiomyomatosis with metastasis was made on histology of the resected uterus and fine-needle aspiration biopsy of the bone. She was managed conservatively, and the lesions are now regressing.

CONCLUSION

Diffuse uterine leiomyomatosis should be considered in pregnant women with a history of uterine fibroids and peripartum hemorrhage.

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Authors+Show Affiliations

Thomas EO
Department of Obstetrics and Gynecology, Rochester General Hospital, Rochester, New York 14621, USA. ethomas3@rochester.rr.com
Gordon J
No affiliation info available
Smith-Thomas S
No affiliation info available
Cramer SF
No affiliation info available

MeSH

AdultBone NeoplasmsCesarean SectionDiagnosis, DifferentialFemaleFetal DeathHumansHysterectomyLeiomyomatosisNeoplasm MetastasisPregnancyPregnancy Complications, NeoplasticPregnancy Trimester, FirstPrenatal DiagnosisTomography, X-Ray ComputedUterine NeoplasmsUterine Rupture

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17267884

Citation

Thomas, Earlando O., et al. "Diffuse Uterine Leiomyomatosis With Uterine Rupture and Benign Metastatic Lesions of the Bone." Obstetrics and Gynecology, vol. 109, no. 2 Pt2, 2007, pp. 528-30.
Thomas EO, Gordon J, Smith-Thomas S, et al. Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone. Obstet Gynecol. 2007;109(2 Pt2):528-30.
Thomas, E. O., Gordon, J., Smith-Thomas, S., & Cramer, S. F. (2007). Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone. Obstetrics and Gynecology, 109(2 Pt2), 528-30.
Thomas EO, et al. Diffuse Uterine Leiomyomatosis With Uterine Rupture and Benign Metastatic Lesions of the Bone. Obstet Gynecol. 2007;109(2 Pt2):528-30. PubMed PMID: 17267884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone. AU - Thomas,Earlando O, AU - Gordon,Jeffrey, AU - Smith-Thomas,Sharon, AU - Cramer,Stewart F, PY - 2007/2/3/pubmed PY - 2007/2/21/medline PY - 2007/2/3/entrez SP - 528 EP - 30 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 109 IS - 2 Pt2 N2 - BACKGROUND: We report a case of diffuse uterine leiomyomatosis in pregnancy complicated by uterine rupture and dissemination to the bone. CASE: A 35-year-old nulliparous woman with a history of uterine leiomyoma presented at term with fetal demise. Failed induction of labor and hemodynamic instability due to uterine rupture resulted in a cesarean hysterectomy. A free-air series performed postoperatively to confirm paralytic ileus revealed multiple lytic bone lesions. The diagnosis of diffuse uterine leiomyomatosis with metastasis was made on histology of the resected uterus and fine-needle aspiration biopsy of the bone. She was managed conservatively, and the lesions are now regressing. CONCLUSION: Diffuse uterine leiomyomatosis should be considered in pregnant women with a history of uterine fibroids and peripartum hemorrhage. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/17267884/Diffuse_uterine_leiomyomatosis_with_uterine_rupture_and_benign_metastatic_lesions_of_the_bone_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=17267884.ui DB - PRIME DP - Unbound Medicine ER -