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Adjuvant chemotherapy in a pregnant woman with endodermal sinus tumor of the ovary.
Obstet Gynecol. 2007 Feb; 109(2 Pt2):537-40.OG

Abstract

BACKGROUND

The administration of chemotherapeutic drugs during pregnancy is rare. We describe a case of malignant ovarian tumor complicating pregnancy.

CASE

After laparotomy at 18 weeks of gestation, the patient received three courses of cisplatin, vinblastine, and bleomycin. Elective cesarean delivery was performed at 31 weeks of gestation. A normal infant was delivered, and no evidence of tumor recurrence was observed. Metastasis to the liver was detected in the fifth month after delivery. However, this was treated successfully with three courses of cisplatin, etoposide, and bleomycin. There was no evidence of recurrence observed at 65 months after the initial treatment.

CONCLUSION

Although the risk of chemotherapy to the fetus cannot be assessed based on a single case, this experience is encouraging.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

17267887

Citation

Motegi, Makoto, et al. "Adjuvant Chemotherapy in a Pregnant Woman With Endodermal Sinus Tumor of the Ovary." Obstetrics and Gynecology, vol. 109, no. 2 Pt2, 2007, pp. 537-40.
Motegi M, Takakura S, Takano H, et al. Adjuvant chemotherapy in a pregnant woman with endodermal sinus tumor of the ovary. Obstet Gynecol. 2007;109(2 Pt2):537-40.
Motegi, M., Takakura, S., Takano, H., Tanaka, T., & Ochiai, K. (2007). Adjuvant chemotherapy in a pregnant woman with endodermal sinus tumor of the ovary. Obstetrics and Gynecology, 109(2 Pt2), 537-40.
Motegi M, et al. Adjuvant Chemotherapy in a Pregnant Woman With Endodermal Sinus Tumor of the Ovary. Obstet Gynecol. 2007;109(2 Pt2):537-40. PubMed PMID: 17267887.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adjuvant chemotherapy in a pregnant woman with endodermal sinus tumor of the ovary. AU - Motegi,Makoto, AU - Takakura,Satoshi, AU - Takano,Hirokuni, AU - Tanaka,Tadao, AU - Ochiai,Kazunori, PY - 2007/2/3/pubmed PY - 2007/2/21/medline PY - 2007/2/3/entrez SP - 537 EP - 40 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 109 IS - 2 Pt2 N2 - BACKGROUND: The administration of chemotherapeutic drugs during pregnancy is rare. We describe a case of malignant ovarian tumor complicating pregnancy. CASE: After laparotomy at 18 weeks of gestation, the patient received three courses of cisplatin, vinblastine, and bleomycin. Elective cesarean delivery was performed at 31 weeks of gestation. A normal infant was delivered, and no evidence of tumor recurrence was observed. Metastasis to the liver was detected in the fifth month after delivery. However, this was treated successfully with three courses of cisplatin, etoposide, and bleomycin. There was no evidence of recurrence observed at 65 months after the initial treatment. CONCLUSION: Although the risk of chemotherapy to the fetus cannot be assessed based on a single case, this experience is encouraging. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/17267887/Adjuvant_chemotherapy_in_a_pregnant_woman_with_endodermal_sinus_tumor_of_the_ovary_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=17267887.ui DB - PRIME DP - Unbound Medicine ER -