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Management of undifferentiated embryonal sarcoma of the liver in pregnancy.
Obstet Gynecol. 2007 Feb; 109(2 Pt2):558-60.OG

Abstract

BACKGROUND

Undifferentiated embryonal sarcoma of the liver is a rare mesenchymal neoplasm with a poor prognosis. Most cases occur in children, with few cases reported in adults. Our patient was a woman whose pregnancy was complicated by the recurrence of metastatic undifferentiated embryonal sarcoma of the liver.

CASE

In the medical literature only two other women have been described with metastatic undifferentiated embryonal sarcoma of the liver in pregnancy. This is the first reported case of undifferentiated embryonal sarcoma of the liver recurring in and requiring treatment during pregnancy. Radio frequency ablation was used to try to control sites of hepatic disease recurrence during the pregnancy. The patient gave birth to a healthy son before requiring further palliative chemotherapy.

CONCLUSION

This case highlights the fact that cancer not infrequently complicates pregnancy and can require treatment, in this case with radio frequency ablation. The case also illustrates a range of complex issues that arise when a patient with cancer has a pregnancy: the doctor's recommendations, the patient's right to choose, the well-being of the infant, and the unpredictable behavior of cancer.

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Authors+Show Affiliations

McCarthy FP
Royal Women's Hospital and Monash Medical Centre, Melbourne, Australia. fergusmccarthy@gmail.com
Harris M
No affiliation info available
Kornman L
No affiliation info available

MeSH

AdultAntineoplastic Combined Chemotherapy ProtocolsCatheter AblationCombined Modality TherapyDiagnosis, DifferentialFemaleHumansInfant, NewbornLiver NeoplasmsMagnetic Resonance ImagingMalePregnancyPregnancy Complications, NeoplasticPrenatal DiagnosisSarcoma

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17267894

Citation

McCarthy, Fergus P., et al. "Management of Undifferentiated Embryonal Sarcoma of the Liver in Pregnancy." Obstetrics and Gynecology, vol. 109, no. 2 Pt2, 2007, pp. 558-60.
McCarthy FP, Harris M, Kornman L. Management of undifferentiated embryonal sarcoma of the liver in pregnancy. Obstet Gynecol. 2007;109(2 Pt2):558-60.
McCarthy, F. P., Harris, M., & Kornman, L. (2007). Management of undifferentiated embryonal sarcoma of the liver in pregnancy. Obstetrics and Gynecology, 109(2 Pt2), 558-60.
McCarthy FP, Harris M, Kornman L. Management of Undifferentiated Embryonal Sarcoma of the Liver in Pregnancy. Obstet Gynecol. 2007;109(2 Pt2):558-60. PubMed PMID: 17267894.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Management of undifferentiated embryonal sarcoma of the liver in pregnancy. AU - McCarthy,Fergus P, AU - Harris,Marion, AU - Kornman,Louise, PY - 2007/2/3/pubmed PY - 2007/2/21/medline PY - 2007/2/3/entrez SP - 558 EP - 60 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 109 IS - 2 Pt2 N2 - BACKGROUND: Undifferentiated embryonal sarcoma of the liver is a rare mesenchymal neoplasm with a poor prognosis. Most cases occur in children, with few cases reported in adults. Our patient was a woman whose pregnancy was complicated by the recurrence of metastatic undifferentiated embryonal sarcoma of the liver. CASE: In the medical literature only two other women have been described with metastatic undifferentiated embryonal sarcoma of the liver in pregnancy. This is the first reported case of undifferentiated embryonal sarcoma of the liver recurring in and requiring treatment during pregnancy. Radio frequency ablation was used to try to control sites of hepatic disease recurrence during the pregnancy. The patient gave birth to a healthy son before requiring further palliative chemotherapy. CONCLUSION: This case highlights the fact that cancer not infrequently complicates pregnancy and can require treatment, in this case with radio frequency ablation. The case also illustrates a range of complex issues that arise when a patient with cancer has a pregnancy: the doctor's recommendations, the patient's right to choose, the well-being of the infant, and the unpredictable behavior of cancer. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/17267894/Management_of_undifferentiated_embryonal_sarcoma_of_the_liver_in_pregnancy_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=17267894.ui DB - PRIME DP - Unbound Medicine ER -