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Resting energy expenditure and insulin resitance in obese patients, differences in women and men.
Eur Rev Med Pharmacol Sci. 2006 Nov-Dec; 10(6):285-9.ER

Abstract

BACKGROUND AND OBJECTIVE

There is little research about the relation of REE and insulin resistance with gender. The aim of our work was to study gender differences in REE and insulin resistance in obese patients.

RESEARCH METHODS AND PROCEDURES

A population of 131 obesity patients was analyzed in a prospective way. The following variables were specifically recorded: age, smoking habit, drinking habit, weight, body mass index (BMI), waist circumference, and waist-hip ratio. Blood pressure, basal glucose, insulin, fibrinogen, and C-reactive protein. HOMA was calculated. An indirect calorimetry, tetrapolar electrical bioimpedance and a serial assessment of nutritional intake with 3 days written food records were performed.

RESULTS

The mean age was 31.7 +/- 9.2 years and the mean BMI 34.4 +/- 5.3. Cardiovascular risk factors were similar in both groups. Anthropometric measurements showed an average waist circunference (107.8 +/- 16.1 cm), waist-to hip ratio (0.93 +/- 0.11), and average weight (94.8 +/- 20.2 kg). Bipolar body electrical bioimpedance showed the next data; fat free mass (55.2 +/- 17.1 kg) and fat mass (35.7 +/- 12.3 kg). Indirect calorimetry showed higher resting metabolic rate (REE) in males (2001.7 +/- 443 Kcal/day vs. 1774.7 +/- 344 Kcal/day; p < 0.05). REE corrected by fat free mass was similar (male 34.2 +/- 17 Kcal/day/kg vs female 39 +/- 11.6 Kcal/day/kg; ns). Nutritional intake and HOMA were similar in males and females. In the multivariate analysis with a dependent variable (RMR), the fat free mass remained in the male model (F = 18.5; p < 0.05), with an increase of 17.8 (CI 95%: 9.1-26.2) kcal/day with each 1 kg of fat free mass adjusted by age. In the female model, the fat free mass remained in the model (F = 1 2.5; p < 0.05), with an increase of 15.2 (CI 95%: 6.3-24.2) kcal/day with each 1 kg of fat free mass adjusted by age.

CONCLUSION

REE was higher in males than females, with a higher influence of fat free mass in males than females. No association between insulin resistance and REE was detected.

Authors+Show Affiliations

Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain. dadluis@yahoo.esNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17274533

Citation

De Luis, D A., et al. "Resting Energy Expenditure and Insulin Resitance in Obese Patients, Differences in Women and Men." European Review for Medical and Pharmacological Sciences, vol. 10, no. 6, 2006, pp. 285-9.
De Luis DA, Aller R, Izaola O. Resting energy expenditure and insulin resitance in obese patients, differences in women and men. Eur Rev Med Pharmacol Sci. 2006;10(6):285-9.
De Luis, D. A., Aller, R., & Izaola, O. (2006). Resting energy expenditure and insulin resitance in obese patients, differences in women and men. European Review for Medical and Pharmacological Sciences, 10(6), 285-9.
De Luis DA, Aller R, Izaola O. Resting Energy Expenditure and Insulin Resitance in Obese Patients, Differences in Women and Men. Eur Rev Med Pharmacol Sci. 2006 Nov-Dec;10(6):285-9. PubMed PMID: 17274533.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Resting energy expenditure and insulin resitance in obese patients, differences in women and men. AU - De Luis,D A, AU - Aller,R, AU - Izaola,O, PY - 2007/2/6/pubmed PY - 2007/2/16/medline PY - 2007/2/6/entrez SP - 285 EP - 9 JF - European review for medical and pharmacological sciences JO - Eur Rev Med Pharmacol Sci VL - 10 IS - 6 N2 - BACKGROUND AND OBJECTIVE: There is little research about the relation of REE and insulin resistance with gender. The aim of our work was to study gender differences in REE and insulin resistance in obese patients. RESEARCH METHODS AND PROCEDURES: A population of 131 obesity patients was analyzed in a prospective way. The following variables were specifically recorded: age, smoking habit, drinking habit, weight, body mass index (BMI), waist circumference, and waist-hip ratio. Blood pressure, basal glucose, insulin, fibrinogen, and C-reactive protein. HOMA was calculated. An indirect calorimetry, tetrapolar electrical bioimpedance and a serial assessment of nutritional intake with 3 days written food records were performed. RESULTS: The mean age was 31.7 +/- 9.2 years and the mean BMI 34.4 +/- 5.3. Cardiovascular risk factors were similar in both groups. Anthropometric measurements showed an average waist circunference (107.8 +/- 16.1 cm), waist-to hip ratio (0.93 +/- 0.11), and average weight (94.8 +/- 20.2 kg). Bipolar body electrical bioimpedance showed the next data; fat free mass (55.2 +/- 17.1 kg) and fat mass (35.7 +/- 12.3 kg). Indirect calorimetry showed higher resting metabolic rate (REE) in males (2001.7 +/- 443 Kcal/day vs. 1774.7 +/- 344 Kcal/day; p < 0.05). REE corrected by fat free mass was similar (male 34.2 +/- 17 Kcal/day/kg vs female 39 +/- 11.6 Kcal/day/kg; ns). Nutritional intake and HOMA were similar in males and females. In the multivariate analysis with a dependent variable (RMR), the fat free mass remained in the male model (F = 18.5; p < 0.05), with an increase of 17.8 (CI 95%: 9.1-26.2) kcal/day with each 1 kg of fat free mass adjusted by age. In the female model, the fat free mass remained in the model (F = 1 2.5; p < 0.05), with an increase of 15.2 (CI 95%: 6.3-24.2) kcal/day with each 1 kg of fat free mass adjusted by age. CONCLUSION: REE was higher in males than females, with a higher influence of fat free mass in males than females. No association between insulin resistance and REE was detected. SN - 1128-3602 UR - https://www.unboundmedicine.com/medline/citation/17274533/Resting_energy_expenditure_and_insulin_resitance_in_obese_patients_differences_in_women_and_men_ L2 - https://medlineplus.gov/obesity.html DB - PRIME DP - Unbound Medicine ER -