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Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress.
J Ethnopharmacol. 2007 May 22; 111(3):443-50.JE

Abstract

Heat-processed Asian ginseng roots (Panax ginseng C.A. Meyer), also known as "red ginseng" in Asia, are reported to have more bioactivity than the no-processed white ginseng roots. Therefore, American fresh ginseng roots (Panax quinquefolius L.) were processed to the red ginseng and examined changes in bioactivity during heating process. The fresh America ginseng roots were steamed at 100 degrees C for 30, 60, 90 and 120 min, and their bioactivities were examined by analyzing the content of ginsenosides and total phenolics, and measuring DPPH and superoxide radical scavenging acivity and their protective effects on V79-4 cells viability and lipid peroxidation. The heating treatment proportionally increased total ginsenosides (4.97%, w/w) content compared with white ginseng (3.27%) and total phenolics from 444.5 mg GAE/100 g to 489.6-574.2 mg GAE/100 g. The antioxidant activity also increased from 285 mg/100 g (vitamin C equivalent) to 353-487 mg/100 g. Heated ginseng showed high levels of DPPH radical scavenging activity (59.5-88.5%) and the high level of superoxide radical scavenging activity (44.2-90.9%). The heated ginseng protected cell viability against H2O2-induced oxidative damage, and enhanced the activities of superoxide dismutase and catalase by dose dependently in V79-4 cells.

Authors+Show Affiliations

Korea Food Research Institute, San 46-1, Baekhyun-Dong, Bundang-Ku, Songnam-Si, Kyunggi-Do 463-746, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17276636

Citation

Kim, Kyung Tack, et al. "Protective Effect of Steamed American Ginseng (Panax Quinquefolius L.) On V79-4 Cells Induced By Oxidative Stress." Journal of Ethnopharmacology, vol. 111, no. 3, 2007, pp. 443-50.
Kim KT, Yoo KM, Lee JW, et al. Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress. J Ethnopharmacol. 2007;111(3):443-50.
Kim, K. T., Yoo, K. M., Lee, J. W., Eom, S. H., Hwang, I. K., & Lee, C. Y. (2007). Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress. Journal of Ethnopharmacology, 111(3), 443-50.
Kim KT, et al. Protective Effect of Steamed American Ginseng (Panax Quinquefolius L.) On V79-4 Cells Induced By Oxidative Stress. J Ethnopharmacol. 2007 May 22;111(3):443-50. PubMed PMID: 17276636.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress. AU - Kim,Kyung Tack, AU - Yoo,Kyung Mi, AU - Lee,Jin Wook, AU - Eom,Seok Hyun, AU - Hwang,In Kyeong, AU - Lee,Chang Y, Y1 - 2007/01/07/ PY - 2006/08/08/received PY - 2006/11/21/revised PY - 2007/2/6/pubmed PY - 2007/7/27/medline PY - 2007/2/6/entrez SP - 443 EP - 50 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 111 IS - 3 N2 - Heat-processed Asian ginseng roots (Panax ginseng C.A. Meyer), also known as "red ginseng" in Asia, are reported to have more bioactivity than the no-processed white ginseng roots. Therefore, American fresh ginseng roots (Panax quinquefolius L.) were processed to the red ginseng and examined changes in bioactivity during heating process. The fresh America ginseng roots were steamed at 100 degrees C for 30, 60, 90 and 120 min, and their bioactivities were examined by analyzing the content of ginsenosides and total phenolics, and measuring DPPH and superoxide radical scavenging acivity and their protective effects on V79-4 cells viability and lipid peroxidation. The heating treatment proportionally increased total ginsenosides (4.97%, w/w) content compared with white ginseng (3.27%) and total phenolics from 444.5 mg GAE/100 g to 489.6-574.2 mg GAE/100 g. The antioxidant activity also increased from 285 mg/100 g (vitamin C equivalent) to 353-487 mg/100 g. Heated ginseng showed high levels of DPPH radical scavenging activity (59.5-88.5%) and the high level of superoxide radical scavenging activity (44.2-90.9%). The heated ginseng protected cell viability against H2O2-induced oxidative damage, and enhanced the activities of superoxide dismutase and catalase by dose dependently in V79-4 cells. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/17276636/Protective_effect_of_steamed_American_ginseng__Panax_quinquefolius_L___on_V79_4_cells_induced_by_oxidative_stress_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-8741(07)00008-6 DB - PRIME DP - Unbound Medicine ER -