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Steroid injection for sinonasal polyps: the University of Virginia experience.
Am J Rhinol. 2007 Jan-Feb; 21(1):64-9.AJ

Abstract

BACKGROUND

Sinonasal polyps are treated with topical steroids, systemic oral steroids, surgical excision, and intrapolyp steroid injection. Use of steroid injection is not widespread because of reported complications. The objective of this study was to evaluate the complications of intrapolyp steroid injections and compare it to the complications of surgical removal of polyps.

METHODS

All patients seen between 1994 and 2003 with a diagnosis of nasal polyps were reviewed retrospectively. Demographics, complications, follow-up, and comorbidities were collected. Frequency of each treatment modality used and complications of each treatment were compared.

RESULTS

Three hundred fifty-eight patients were in the study with a mean follow-up of 30 months. Respiratory comorbidities were asthma alone (35%), aspirin triad (16%), and cystic fibrosis (15%). Other comorbidities were smokers (21%). Treatment modalities were medical treatment alone (14%); medical treatment and steroid injections (19%); medical treatment and surgery (33%); and medical treatment, injections, and surgery (34%). Patients who underwent injection had fewer surgeries (p < 0.001). There was 1 minor complication associated with 1495 injections and 11 major and 16 minor complications associated with the 310 surgeries. The differences in complication rates were statistically significant (p < 0.001). There was no significant difference in demographics, follow-up, or comorbidities between patients who received injections and patients who underwent surgery.

CONCLUSION

Intrapolyp steroid injection is associated with a significantly lower rate of complication than is surgical excision of sinonasal polyps. Steroid injection also may decrease the need for further surgical intervention of polyps.

Authors+Show Affiliations

Department of Otolaryngology and Head and Neck Surgery, University of Virginia Health System, Charlottesville, Virginia, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17283564

Citation

Becker, Samuel S., et al. "Steroid Injection for Sinonasal Polyps: the University of Virginia Experience." American Journal of Rhinology, vol. 21, no. 1, 2007, pp. 64-9.
Becker SS, Rasamny JK, Han JK, et al. Steroid injection for sinonasal polyps: the University of Virginia experience. Am J Rhinol. 2007;21(1):64-9.
Becker, S. S., Rasamny, J. K., Han, J. K., Patrie, J., & Gross, C. W. (2007). Steroid injection for sinonasal polyps: the University of Virginia experience. American Journal of Rhinology, 21(1), 64-9.
Becker SS, et al. Steroid Injection for Sinonasal Polyps: the University of Virginia Experience. Am J Rhinol. 2007 Jan-Feb;21(1):64-9. PubMed PMID: 17283564.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Steroid injection for sinonasal polyps: the University of Virginia experience. AU - Becker,Samuel S, AU - Rasamny,J K, AU - Han,Joseph K, AU - Patrie,James, AU - Gross,Charles W, PY - 2007/2/8/pubmed PY - 2007/3/7/medline PY - 2007/2/8/entrez SP - 64 EP - 9 JF - American journal of rhinology JO - Am J Rhinol VL - 21 IS - 1 N2 - BACKGROUND: Sinonasal polyps are treated with topical steroids, systemic oral steroids, surgical excision, and intrapolyp steroid injection. Use of steroid injection is not widespread because of reported complications. The objective of this study was to evaluate the complications of intrapolyp steroid injections and compare it to the complications of surgical removal of polyps. METHODS: All patients seen between 1994 and 2003 with a diagnosis of nasal polyps were reviewed retrospectively. Demographics, complications, follow-up, and comorbidities were collected. Frequency of each treatment modality used and complications of each treatment were compared. RESULTS: Three hundred fifty-eight patients were in the study with a mean follow-up of 30 months. Respiratory comorbidities were asthma alone (35%), aspirin triad (16%), and cystic fibrosis (15%). Other comorbidities were smokers (21%). Treatment modalities were medical treatment alone (14%); medical treatment and steroid injections (19%); medical treatment and surgery (33%); and medical treatment, injections, and surgery (34%). Patients who underwent injection had fewer surgeries (p < 0.001). There was 1 minor complication associated with 1495 injections and 11 major and 16 minor complications associated with the 310 surgeries. The differences in complication rates were statistically significant (p < 0.001). There was no significant difference in demographics, follow-up, or comorbidities between patients who received injections and patients who underwent surgery. CONCLUSION: Intrapolyp steroid injection is associated with a significantly lower rate of complication than is surgical excision of sinonasal polyps. Steroid injection also may decrease the need for further surgical intervention of polyps. SN - 1050-6586 UR - https://www.unboundmedicine.com/medline/citation/17283564/Steroid_injection_for_sinonasal_polyps:_the_University_of_Virginia_experience_ L2 - https://medlineplus.gov/steroids.html DB - PRIME DP - Unbound Medicine ER -