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Automated Neuropsychological Test Battery (CANTAB) in mild cognitive impairment and in Alzheimer's disease.

Abstract

Neuropsychological deficits, such as poor episodic memory, are consistent features of mild cognitive impairment and also that of early stage of dementia. The aim of the present study was to detect cognitive dysfunction among patients with Alzheimer's disease or with mild cognitive impairment (MCI), which refers to a transitional state between the cognition of normal aeging and mild dementia regarded as a high-risk condition for the development of clinically probable Alzheimer's disease (AD). Computerized tests of memory, attention and executive functions were studied in groups of AD subjects (n=15) and MCI subjects (n=25). On all measures, the performance of the AD group was significantly weaker compared to healthy individuals or to the MCI group. The performance of both the AD and MCI patients in the Paired Associate Learning test was significantly impaired, which may suggest that MCI patients are already in the early stages of the disease.

Authors+Show Affiliations

Department of Psychiatry, University of Debrecen Medical and Health Science Center, 98, Nagyerdei krt., H-4012 Debrecen, Hungary. egerhazi@dote.huNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17289240

Citation

Egerházi, Anikó, et al. "Automated Neuropsychological Test Battery (CANTAB) in Mild Cognitive Impairment and in Alzheimer's Disease." Progress in Neuro-psychopharmacology & Biological Psychiatry, vol. 31, no. 3, 2007, pp. 746-51.
Egerházi A, Berecz R, Bartók E, et al. Automated Neuropsychological Test Battery (CANTAB) in mild cognitive impairment and in Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(3):746-51.
Egerházi, A., Berecz, R., Bartók, E., & Degrell, I. (2007). Automated Neuropsychological Test Battery (CANTAB) in mild cognitive impairment and in Alzheimer's disease. Progress in Neuro-psychopharmacology & Biological Psychiatry, 31(3), pp. 746-51.
Egerházi A, et al. Automated Neuropsychological Test Battery (CANTAB) in Mild Cognitive Impairment and in Alzheimer's Disease. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Apr 13;31(3):746-51. PubMed PMID: 17289240.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Automated Neuropsychological Test Battery (CANTAB) in mild cognitive impairment and in Alzheimer's disease. AU - Egerházi,Anikó, AU - Berecz,Roland, AU - Bartók,Eniko, AU - Degrell,István, Y1 - 2007/01/16/ PY - 2006/06/29/received PY - 2007/01/09/revised PY - 2007/01/10/accepted PY - 2007/2/10/pubmed PY - 2007/6/27/medline PY - 2007/2/10/entrez SP - 746 EP - 51 JF - Progress in neuro-psychopharmacology & biological psychiatry JO - Prog. Neuropsychopharmacol. Biol. Psychiatry VL - 31 IS - 3 N2 - Neuropsychological deficits, such as poor episodic memory, are consistent features of mild cognitive impairment and also that of early stage of dementia. The aim of the present study was to detect cognitive dysfunction among patients with Alzheimer's disease or with mild cognitive impairment (MCI), which refers to a transitional state between the cognition of normal aeging and mild dementia regarded as a high-risk condition for the development of clinically probable Alzheimer's disease (AD). Computerized tests of memory, attention and executive functions were studied in groups of AD subjects (n=15) and MCI subjects (n=25). On all measures, the performance of the AD group was significantly weaker compared to healthy individuals or to the MCI group. The performance of both the AD and MCI patients in the Paired Associate Learning test was significantly impaired, which may suggest that MCI patients are already in the early stages of the disease. SN - 0278-5846 UR - https://www.unboundmedicine.com/medline/citation/17289240/Automated_Neuropsychological_Test_Battery__CANTAB__in_mild_cognitive_impairment_and_in_Alzheimer's_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0278-5846(07)00021-8 DB - PRIME DP - Unbound Medicine ER -