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Walking decreased risk of cardiovascular disease mortality in older adults with diabetes.
J Clin Epidemiol 2007; 60(3):309-17JC

Abstract

OBJECTIVE

This study examines the association of walking with mortality in persons with type 2 diabetes compared to those with normal glucose tolerance.

STUDY DESIGN AND SETTING

This prospective study included community-dwelling adults from the Rancho Bernardo Study aged 50-90 years in 1984-86 who had type 2 diabetes (n=347) or normal glucose tolerance (n=1,317). During the 10-year follow up, Cox proportional hazards modeling was used to model time until death from all causes (n=538), coronary heart disease (CHD, n=143), other cardiovascular disease (non-CHD CVD, n=138), and other causes (n=257) while adjusting for multiple potential confounders.

RESULTS

After adjusting for sex, age, smoking, body mass index, alcohol, exercise, history of CHD, and other covariates, adults with diabetes who walked > or =1 mile per day were half as likely to die from all causes combined (hazard ratio [HR]=0.54; 95% confidence interval [CI]: 0.33, 0.88), and less than one-fifth as likely to die from non-CHD CVD (HR=0.19; 95% CI: 0.04, 0.86) compared to adults with diabetes who did not walk. Walking was also protective among adults with normal glucose tolerance (HR=0.55; 95% CI: 0.32, 0.96).

CONCLUSION

Results suggest walking > or =1 mile per day may provide strong protection from all-cause and non-CHD CVD mortality in older adults with diabetes.

Authors+Show Affiliations

Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive 0607, La Jolla, CA 92093-0607, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

17292026

Citation

Smith, Tyler C., et al. "Walking Decreased Risk of Cardiovascular Disease Mortality in Older Adults With Diabetes." Journal of Clinical Epidemiology, vol. 60, no. 3, 2007, pp. 309-17.
Smith TC, Wingard DL, Smith B, et al. Walking decreased risk of cardiovascular disease mortality in older adults with diabetes. J Clin Epidemiol. 2007;60(3):309-17.
Smith, T. C., Wingard, D. L., Smith, B., Kritz-Silverstein, D., & Barrett-Connor, E. (2007). Walking decreased risk of cardiovascular disease mortality in older adults with diabetes. Journal of Clinical Epidemiology, 60(3), pp. 309-17.
Smith TC, et al. Walking Decreased Risk of Cardiovascular Disease Mortality in Older Adults With Diabetes. J Clin Epidemiol. 2007;60(3):309-17. PubMed PMID: 17292026.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Walking decreased risk of cardiovascular disease mortality in older adults with diabetes. AU - Smith,Tyler C, AU - Wingard,Deborah L, AU - Smith,Besa, AU - Kritz-Silverstein,Donna, AU - Barrett-Connor,Elizabeth, Y1 - 2006/10/02/ PY - 2005/11/21/received PY - 2006/05/05/revised PY - 2006/06/02/accepted PY - 2007/2/13/pubmed PY - 2007/3/21/medline PY - 2007/2/13/entrez SP - 309 EP - 17 JF - Journal of clinical epidemiology JO - J Clin Epidemiol VL - 60 IS - 3 N2 - OBJECTIVE: This study examines the association of walking with mortality in persons with type 2 diabetes compared to those with normal glucose tolerance. STUDY DESIGN AND SETTING: This prospective study included community-dwelling adults from the Rancho Bernardo Study aged 50-90 years in 1984-86 who had type 2 diabetes (n=347) or normal glucose tolerance (n=1,317). During the 10-year follow up, Cox proportional hazards modeling was used to model time until death from all causes (n=538), coronary heart disease (CHD, n=143), other cardiovascular disease (non-CHD CVD, n=138), and other causes (n=257) while adjusting for multiple potential confounders. RESULTS: After adjusting for sex, age, smoking, body mass index, alcohol, exercise, history of CHD, and other covariates, adults with diabetes who walked > or =1 mile per day were half as likely to die from all causes combined (hazard ratio [HR]=0.54; 95% confidence interval [CI]: 0.33, 0.88), and less than one-fifth as likely to die from non-CHD CVD (HR=0.19; 95% CI: 0.04, 0.86) compared to adults with diabetes who did not walk. Walking was also protective among adults with normal glucose tolerance (HR=0.55; 95% CI: 0.32, 0.96). CONCLUSION: Results suggest walking > or =1 mile per day may provide strong protection from all-cause and non-CHD CVD mortality in older adults with diabetes. SN - 0895-4356 UR - https://www.unboundmedicine.com/medline/citation/17292026/Walking_decreased_risk_of_cardiovascular_disease_mortality_in_older_adults_with_diabetes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0895-4356(06)00256-3 DB - PRIME DP - Unbound Medicine ER -