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Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys.
J Affect Disord. 2007 Nov; 103(1-3):113-20.JA

Abstract

BACKGROUND

Prior research on the association between affective disorders and physical conditions has been carried out in developed countries, usually in clinical populations, on a limited range of mental disorders and physical conditions, and has seldom taken into account the comorbidity between depressive and anxiety disorders.

METHODS

Eighteen general population surveys were carried out among adults in 17 countries as part of the World Mental Health Surveys initiative (N=42, 249). DSM-IV depressive and anxiety disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). Chronic physical conditions were ascertained via a standard checklist. The relationship between mental disorders and physical conditions was assessed by considering depressive and anxiety disorders independently (depression without anxiety; anxiety without depression) and conjointly (depression plus anxiety).

RESULTS

All physical conditions were significantly associated with depressive and/or anxiety disorders but there was variation in the strength of association (ORs 1.2-4.5). Non-comorbid depressive and anxiety disorders were associated in equal degree with physical conditions. Comorbid depressive-anxiety disorder was more strongly associated with several physical conditions than were single mental disorders.

LIMITATIONS

Physical conditions were ascertained via self report, though for a number of conditions this was self-report of diagnosis by a physician.

CONCLUSIONS

Given the prevalence and clinical consequences of the co-occurrence of mental and physical disorders, attention to their comorbidity should remain a clinical and research priority.

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Authors+Show Affiliations

Scott KM
Department of Psychological Medicine, Wellington School of Medicine and Health Sciences, PO Box 7343 Wellington South, New Zealand. kate.scott@otago.ac.nz
Bruffaerts R
No affiliation info available
Tsang A
No affiliation info available
Ormel J
No affiliation info available
Alonso J
No affiliation info available
Angermeyer MC
No affiliation info available
Benjet C
No affiliation info available
Bromet E
No affiliation info available
de Girolamo G
No affiliation info available
de Graaf R
No affiliation info available
Gasquet I
No affiliation info available
Gureje O
No affiliation info available
Haro JM
No affiliation info available
He Y
No affiliation info available
Kessler RC
No affiliation info available
Levinson D
No affiliation info available
Mneimneh ZN
No affiliation info available
Oakley Browne MA
No affiliation info available
Posada-Villa J
No affiliation info available
Stein DJ
No affiliation info available
Takeshima T
No affiliation info available
Von Korff M
No affiliation info available

MeSH

AdultAgedAnxiety DisordersChronic DiseaseComorbidityCross-Cultural ComparisonCross-Sectional StudiesDepressive Disorder, MajorDysthymic DisorderFemaleHealth SurveysHumansMaleMiddle AgedSick Role

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17292480

Citation

Scott, K M., et al. "Depression-anxiety Relationships With Chronic Physical Conditions: Results From the World Mental Health Surveys." Journal of Affective Disorders, vol. 103, no. 1-3, 2007, pp. 113-20.
Scott KM, Bruffaerts R, Tsang A, et al. Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys. J Affect Disord. 2007;103(1-3):113-20.
Scott, K. M., Bruffaerts, R., Tsang, A., Ormel, J., Alonso, J., Angermeyer, M. C., Benjet, C., Bromet, E., de Girolamo, G., de Graaf, R., Gasquet, I., Gureje, O., Haro, J. M., He, Y., Kessler, R. C., Levinson, D., Mneimneh, Z. N., Oakley Browne, M. A., Posada-Villa, J., ... Von Korff, M. (2007). Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys. Journal of Affective Disorders, 103(1-3), 113-20.
Scott KM, et al. Depression-anxiety Relationships With Chronic Physical Conditions: Results From the World Mental Health Surveys. J Affect Disord. 2007;103(1-3):113-20. PubMed PMID: 17292480.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys. AU - Scott,K M, AU - Bruffaerts,R, AU - Tsang,A, AU - Ormel,J, AU - Alonso,J, AU - Angermeyer,M C, AU - Benjet,C, AU - Bromet,E, AU - de Girolamo,G, AU - de Graaf,R, AU - Gasquet,I, AU - Gureje,O, AU - Haro,J M, AU - He,Y, AU - Kessler,R C, AU - Levinson,D, AU - Mneimneh,Z N, AU - Oakley Browne,M A, AU - Posada-Villa,J, AU - Stein,D J, AU - Takeshima,T, AU - Von Korff,M, Y1 - 2007/02/09/ PY - 2006/11/02/received PY - 2007/01/05/revised PY - 2007/01/09/accepted PY - 2007/2/13/pubmed PY - 2008/2/8/medline PY - 2007/2/13/entrez SP - 113 EP - 20 JF - Journal of affective disorders JO - J Affect Disord VL - 103 IS - 1-3 N2 - BACKGROUND: Prior research on the association between affective disorders and physical conditions has been carried out in developed countries, usually in clinical populations, on a limited range of mental disorders and physical conditions, and has seldom taken into account the comorbidity between depressive and anxiety disorders. METHODS: Eighteen general population surveys were carried out among adults in 17 countries as part of the World Mental Health Surveys initiative (N=42, 249). DSM-IV depressive and anxiety disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). Chronic physical conditions were ascertained via a standard checklist. The relationship between mental disorders and physical conditions was assessed by considering depressive and anxiety disorders independently (depression without anxiety; anxiety without depression) and conjointly (depression plus anxiety). RESULTS: All physical conditions were significantly associated with depressive and/or anxiety disorders but there was variation in the strength of association (ORs 1.2-4.5). Non-comorbid depressive and anxiety disorders were associated in equal degree with physical conditions. Comorbid depressive-anxiety disorder was more strongly associated with several physical conditions than were single mental disorders. LIMITATIONS: Physical conditions were ascertained via self report, though for a number of conditions this was self-report of diagnosis by a physician. CONCLUSIONS: Given the prevalence and clinical consequences of the co-occurrence of mental and physical disorders, attention to their comorbidity should remain a clinical and research priority. SN - 0165-0327 UR - https://www.unboundmedicine.com/medline/citation/17292480/Depression_anxiety_relationships_with_chronic_physical_conditions:_results_from_the_World_Mental_Health_Surveys_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-0327(07)00017-1 DB - PRIME DP - Unbound Medicine ER -