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Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects.
Eur J Clin Nutr. 2007 Dec; 61(12):1423-8.EJ

Abstract

OBJECTIVE

Constipation is a common problem in the elderly. Dietary fibre is recommended for its treatment. The aim was to examine whether yoghurt containing galacto-oligosaccharides (GOS), prunes and linseed relieve constipation in elderly subjects.

DESIGN

A randomized, double-blinded, cross-over study.

SETTING

Free-living subjects.

SUBJECTS

A group of 43 elderly subjects with self-reported constipation (mean age 76 years, range 61-92 years, 32 females, 11 males).

INTERVENTIONS

The study consisted of a 2-week baseline period and 2, 3-week dietary interventions, with a 2-week wash-out period between the interventions. During the interventions, the subjects ingested, in random order, 260 g/day of either control yoghurt or test yoghurt containing GOS (12 g/day), prunes (12 g/day) and linseed (6 g/day). The use of laxatives was controlled and only allowed after 2 days without defecation.

RESULTS

Defecation frequency was 5.7 times/week during the baseline period. During the test yoghurt period, defecation frequency was higher (8.0 vs 7.1 times/week, P=0.011), defecation was easier (on the scale 0-3, 1.3 vs 1.5, P=0.010), and there was a tendency towards softer stools (on the scale 0-3, 2.1 vs 2.2, P=0.059) compared with the control yoghurt period. The subjects felt that the test yoghurt relieved constipation more effectively than the control yoghurt (P=0.005). The sum of gastrointestinal symptoms did not differ between the interventions. The use of laxatives remained constant throughout the study.

CONCLUSIONS

Daily intake of yoghurt containing GOS, prunes and linseed reduced the severity of constipation in elderly subjects with mild constipation.

SPONSORSHIP

Valio Ltd, R&D.

Authors+Show Affiliations

Valio Ltd R&D, Helsinki, Finland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17299467

Citation

Sairanen, U, et al. "Yoghurt Containing Galacto-oligosaccharides, Prunes and Linseed Reduces the Severity of Mild Constipation in Elderly Subjects." European Journal of Clinical Nutrition, vol. 61, no. 12, 2007, pp. 1423-8.
Sairanen U, Piirainen L, Nevala R, et al. Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. Eur J Clin Nutr. 2007;61(12):1423-8.
Sairanen, U., Piirainen, L., Nevala, R., & Korpela, R. (2007). Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. European Journal of Clinical Nutrition, 61(12), 1423-8.
Sairanen U, et al. Yoghurt Containing Galacto-oligosaccharides, Prunes and Linseed Reduces the Severity of Mild Constipation in Elderly Subjects. Eur J Clin Nutr. 2007;61(12):1423-8. PubMed PMID: 17299467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. AU - Sairanen,U, AU - Piirainen,L, AU - Nevala,R, AU - Korpela,R, Y1 - 2007/02/14/ PY - 2007/2/15/pubmed PY - 2008/2/20/medline PY - 2007/2/15/entrez SP - 1423 EP - 8 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 61 IS - 12 N2 - OBJECTIVE: Constipation is a common problem in the elderly. Dietary fibre is recommended for its treatment. The aim was to examine whether yoghurt containing galacto-oligosaccharides (GOS), prunes and linseed relieve constipation in elderly subjects. DESIGN: A randomized, double-blinded, cross-over study. SETTING: Free-living subjects. SUBJECTS: A group of 43 elderly subjects with self-reported constipation (mean age 76 years, range 61-92 years, 32 females, 11 males). INTERVENTIONS: The study consisted of a 2-week baseline period and 2, 3-week dietary interventions, with a 2-week wash-out period between the interventions. During the interventions, the subjects ingested, in random order, 260 g/day of either control yoghurt or test yoghurt containing GOS (12 g/day), prunes (12 g/day) and linseed (6 g/day). The use of laxatives was controlled and only allowed after 2 days without defecation. RESULTS: Defecation frequency was 5.7 times/week during the baseline period. During the test yoghurt period, defecation frequency was higher (8.0 vs 7.1 times/week, P=0.011), defecation was easier (on the scale 0-3, 1.3 vs 1.5, P=0.010), and there was a tendency towards softer stools (on the scale 0-3, 2.1 vs 2.2, P=0.059) compared with the control yoghurt period. The subjects felt that the test yoghurt relieved constipation more effectively than the control yoghurt (P=0.005). The sum of gastrointestinal symptoms did not differ between the interventions. The use of laxatives remained constant throughout the study. CONCLUSIONS: Daily intake of yoghurt containing GOS, prunes and linseed reduced the severity of constipation in elderly subjects with mild constipation. SPONSORSHIP: Valio Ltd, R&D. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/17299467/Yoghurt_containing_galacto_oligosaccharides_prunes_and_linseed_reduces_the_severity_of_mild_constipation_in_elderly_subjects_ L2 - https://doi.org/10.1038/sj.ejcn.1602670 DB - PRIME DP - Unbound Medicine ER -