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[Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration].
Rev Esp Anestesiol Reanim. 2006 Dec; 53(10):626-32.RE

Abstract

BACKGROUND

The continuous femoral nerve block is used for postoperative orthopedic analgesia.

OBJECTIVE

To evaluate 2 concentrations of bupivacaine with clonidine in 3 methods of administration for performing a continuous femoral nerve block.

MATERIAL AND METHODS

Randomized controlled trial in ASA 1-2 patients in 6 groups. In groups 1, 2, and 3, the combination used was 0.125% bupivacaine plus clonidine. In groups la, 2a, and 3a, the combination was 0.0625% bupivacaine plus clonidine. Methods of administration were as follows: groups 1 and la, 10 mL x h(-1) in continuous infusion; groups 2 and 2a, 5 mL h x (-1) in continuous infusion plus 2.5 mL every 30 minutes through a patient-controlled analgesia (PCA) system; groups 3 and 3a, 5 mL every 30 minutes in a PCA system. Pain on a visual analog scale (VAS) and amounts of bupivacaine and morphine used were recorded 2 and 48 hours after surgery.

RESULTS

A total of 105 patients were enrolled: 17 in group 1, 18 in group la, 18 in group 2, 17 in group 2a, 17 in group 3, and 18 in group 3a. No significant differences between any of the 6 groups were observed for patient characteristics, postoperative VAS scores, or morphine use.

CONCLUSIONS

A continuous femoral nerve block is useful for managing pain after anterior cruciate ligament surgery. The application of 5 mL x h(-1) in continuous infusion or in PCA system bolus doses provides excellent postoperative analgesia. Use of 0.0625% bupivacaine decreases overall consumption of analgesic and is not detrimental to quality of analgesia.

Authors+Show Affiliations

Servicio de Anestesiología, Hospital Clinico Regional de Concepción, Chile. vcontreras@netanestesia.clNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial

Language

spa

PubMed ID

17302076

Citation

Contreras-Dominguez, V, et al. "[Femoral Nerve Block for Postoperative Analgesia After Anterior Cruciate Ligament Reconstruction: Comparison of 2 Concentrations of Bupivacaine With Clonidine in 3 Modes of Administration]." Revista Espanola De Anestesiologia Y Reanimacion, vol. 53, no. 10, 2006, pp. 626-32.
Contreras-Dominguez V, Carbonell-Bellolioa P, Ojeda-Greciet A, et al. [Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration]. Rev Esp Anestesiol Reanim. 2006;53(10):626-32.
Contreras-Dominguez, V., Carbonell-Bellolioa, P., Ojeda-Greciet, A., & Sanzana, E. S. (2006). [Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration]. Revista Espanola De Anestesiologia Y Reanimacion, 53(10), 626-32.
Contreras-Dominguez V, et al. [Femoral Nerve Block for Postoperative Analgesia After Anterior Cruciate Ligament Reconstruction: Comparison of 2 Concentrations of Bupivacaine With Clonidine in 3 Modes of Administration]. Rev Esp Anestesiol Reanim. 2006;53(10):626-32. PubMed PMID: 17302076.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration]. AU - Contreras-Dominguez,V, AU - Carbonell-Bellolioa,P, AU - Ojeda-Greciet,A, AU - Sanzana,E S, PY - 2007/2/17/pubmed PY - 2007/4/5/medline PY - 2007/2/17/entrez SP - 626 EP - 32 JF - Revista espanola de anestesiologia y reanimacion JO - Rev Esp Anestesiol Reanim VL - 53 IS - 10 N2 - BACKGROUND: The continuous femoral nerve block is used for postoperative orthopedic analgesia. OBJECTIVE: To evaluate 2 concentrations of bupivacaine with clonidine in 3 methods of administration for performing a continuous femoral nerve block. MATERIAL AND METHODS: Randomized controlled trial in ASA 1-2 patients in 6 groups. In groups 1, 2, and 3, the combination used was 0.125% bupivacaine plus clonidine. In groups la, 2a, and 3a, the combination was 0.0625% bupivacaine plus clonidine. Methods of administration were as follows: groups 1 and la, 10 mL x h(-1) in continuous infusion; groups 2 and 2a, 5 mL h x (-1) in continuous infusion plus 2.5 mL every 30 minutes through a patient-controlled analgesia (PCA) system; groups 3 and 3a, 5 mL every 30 minutes in a PCA system. Pain on a visual analog scale (VAS) and amounts of bupivacaine and morphine used were recorded 2 and 48 hours after surgery. RESULTS: A total of 105 patients were enrolled: 17 in group 1, 18 in group la, 18 in group 2, 17 in group 2a, 17 in group 3, and 18 in group 3a. No significant differences between any of the 6 groups were observed for patient characteristics, postoperative VAS scores, or morphine use. CONCLUSIONS: A continuous femoral nerve block is useful for managing pain after anterior cruciate ligament surgery. The application of 5 mL x h(-1) in continuous infusion or in PCA system bolus doses provides excellent postoperative analgesia. Use of 0.0625% bupivacaine decreases overall consumption of analgesic and is not detrimental to quality of analgesia. SN - 0034-9356 UR - https://www.unboundmedicine.com/medline/citation/17302076/[Femoral_nerve_block_for_postoperative_analgesia_after_anterior_cruciate_ligament_reconstruction:_comparison_of_2_concentrations_of_bupivacaine_with_clonidine_in_3_modes_of_administration]_ L2 - https://medlineplus.gov/plasticandcosmeticsurgery.html DB - PRIME DP - Unbound Medicine ER -