Tags

Type your tag names separated by a space and hit enter

Viscosity and wettability of animal mucin solutions and human saliva.
Oral Dis. 2007 Mar; 13(2):181-6.OD

Abstract

OBJECTIVE

The purpose of this study was to compare viscosity and wettability between animal mucin solutions and human saliva.

MATERIALS AND METHODS

Human whole and glandular saliva, porcine gastric mucin, bovine submaxillary mucin, and a mucin-based saliva substitute were used. Viscosity was measured with a cone-and-plate digital viscometer, while wettability on acrylic resin and Co-Cr alloy was determined by the contact angle.

RESULTS

The viscosity of animal mucin solutions was proportional to mucin concentration, with the animal mucin solution of concentration 5.0 mg ml(-1) displaying similar viscosity to stimulated whole saliva. A decrease in contact angle was found with increasing animal mucin concentration. For the saliva samples tested, viscosity increased in the following order: stimulated parotid saliva, stimulated whole saliva, unstimulated whole saliva, stimulated submandibular-sublingual saliva. Contact angles of human saliva on the tested solid phases were inversely correlated with viscosity. Contact angles of human saliva on acrylic resin were much lower than those of animal mucin solutions and of those on Co-Cr alloy (P < 0.01).

CONCLUSIONS

The effectiveness of animal mucin solutions in terms of their rheological properties was objectively confirmed, indicating a vital role for mucin in proper oral function as well as the development of effective salivary substitutes.

Authors+Show Affiliations

Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Yunkeun-Dong 28, Chongro-Ku, Seoul 110-749, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17305620

Citation

Park, M-S, et al. "Viscosity and Wettability of Animal Mucin Solutions and Human Saliva." Oral Diseases, vol. 13, no. 2, 2007, pp. 181-6.
Park MS, Chung JW, Kim YK, et al. Viscosity and wettability of animal mucin solutions and human saliva. Oral Dis. 2007;13(2):181-6.
Park, M. S., Chung, J. W., Kim, Y. K., Chung, S. C., & Kho, H. S. (2007). Viscosity and wettability of animal mucin solutions and human saliva. Oral Diseases, 13(2), 181-6.
Park MS, et al. Viscosity and Wettability of Animal Mucin Solutions and Human Saliva. Oral Dis. 2007;13(2):181-6. PubMed PMID: 17305620.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Viscosity and wettability of animal mucin solutions and human saliva. AU - Park,M-S, AU - Chung,J-W, AU - Kim,Y-K, AU - Chung,S-C, AU - Kho,H-S, PY - 2007/2/20/pubmed PY - 2007/4/27/medline PY - 2007/2/20/entrez SP - 181 EP - 6 JF - Oral diseases JO - Oral Dis VL - 13 IS - 2 N2 - OBJECTIVE: The purpose of this study was to compare viscosity and wettability between animal mucin solutions and human saliva. MATERIALS AND METHODS: Human whole and glandular saliva, porcine gastric mucin, bovine submaxillary mucin, and a mucin-based saliva substitute were used. Viscosity was measured with a cone-and-plate digital viscometer, while wettability on acrylic resin and Co-Cr alloy was determined by the contact angle. RESULTS: The viscosity of animal mucin solutions was proportional to mucin concentration, with the animal mucin solution of concentration 5.0 mg ml(-1) displaying similar viscosity to stimulated whole saliva. A decrease in contact angle was found with increasing animal mucin concentration. For the saliva samples tested, viscosity increased in the following order: stimulated parotid saliva, stimulated whole saliva, unstimulated whole saliva, stimulated submandibular-sublingual saliva. Contact angles of human saliva on the tested solid phases were inversely correlated with viscosity. Contact angles of human saliva on acrylic resin were much lower than those of animal mucin solutions and of those on Co-Cr alloy (P < 0.01). CONCLUSIONS: The effectiveness of animal mucin solutions in terms of their rheological properties was objectively confirmed, indicating a vital role for mucin in proper oral function as well as the development of effective salivary substitutes. SN - 1354-523X UR - https://www.unboundmedicine.com/medline/citation/17305620/Viscosity_and_wettability_of_animal_mucin_solutions_and_human_saliva_ L2 - https://doi.org/10.1111/j.1601-0825.2006.01263.x DB - PRIME DP - Unbound Medicine ER -