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The 1,450-nm diode laser reduces sebum production in facial skin: a possible mode of action of its effectiveness for the treatment of acne vulgaris.
Lasers Surg Med. 2007 Feb; 39(2):189-92.LS

Abstract

BACKGROUND AND OBJECTIVES

Over the last several years, several light-based systems have been employed for the treatment of acne vulgaris. The 1,450-nm diode laser has been shown to improve acne, and this has been suggested to be due to effects on sebaceous glands. However, an effect on sebum production has not been demonstrated. The objective of this study was to evaluate if the 1,450-nm diode laser indeed reduces sebum production.

STUDY DESIGN/MATERIALS AND METHODS

Eight patients with a history of acne were recruited and treated with the 1,450-nm diode laser on the right side of the nose over a 6-week period, for a total of three treatments. Sebum production was quantified using the Sebutape method.

RESULTS

The number of sebum-producing follicles was reduced by 8.5 and 16.7% at weeks 4 and 6, respectively (P<0.05). A significant reduction in total collected sebum (-18%) was observed at week 6.

CONCLUSION

This data suggests that the clinical effectiveness of the 1,450-nm diode laser may be based, at least in part, on its effects on sebaceous glands, with subsequent reduction in sebum production.

Authors+Show Affiliations

Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17311272

Citation

Perez-Maldonado, Adrian, et al. "The 1,450-nm Diode Laser Reduces Sebum Production in Facial Skin: a Possible Mode of Action of Its Effectiveness for the Treatment of Acne Vulgaris." Lasers in Surgery and Medicine, vol. 39, no. 2, 2007, pp. 189-92.
Perez-Maldonado A, Rünger TM, Krejci-Papa N. The 1,450-nm diode laser reduces sebum production in facial skin: a possible mode of action of its effectiveness for the treatment of acne vulgaris. Lasers Surg Med. 2007;39(2):189-92.
Perez-Maldonado, A., Rünger, T. M., & Krejci-Papa, N. (2007). The 1,450-nm diode laser reduces sebum production in facial skin: a possible mode of action of its effectiveness for the treatment of acne vulgaris. Lasers in Surgery and Medicine, 39(2), 189-92.
Perez-Maldonado A, Rünger TM, Krejci-Papa N. The 1,450-nm Diode Laser Reduces Sebum Production in Facial Skin: a Possible Mode of Action of Its Effectiveness for the Treatment of Acne Vulgaris. Lasers Surg Med. 2007;39(2):189-92. PubMed PMID: 17311272.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The 1,450-nm diode laser reduces sebum production in facial skin: a possible mode of action of its effectiveness for the treatment of acne vulgaris. AU - Perez-Maldonado,Adrian, AU - Rünger,Thomas M, AU - Krejci-Papa,Niels, PY - 2007/2/22/pubmed PY - 2007/6/19/medline PY - 2007/2/22/entrez SP - 189 EP - 92 JF - Lasers in surgery and medicine JO - Lasers Surg Med VL - 39 IS - 2 N2 - BACKGROUND AND OBJECTIVES: Over the last several years, several light-based systems have been employed for the treatment of acne vulgaris. The 1,450-nm diode laser has been shown to improve acne, and this has been suggested to be due to effects on sebaceous glands. However, an effect on sebum production has not been demonstrated. The objective of this study was to evaluate if the 1,450-nm diode laser indeed reduces sebum production. STUDY DESIGN/MATERIALS AND METHODS: Eight patients with a history of acne were recruited and treated with the 1,450-nm diode laser on the right side of the nose over a 6-week period, for a total of three treatments. Sebum production was quantified using the Sebutape method. RESULTS: The number of sebum-producing follicles was reduced by 8.5 and 16.7% at weeks 4 and 6, respectively (P<0.05). A significant reduction in total collected sebum (-18%) was observed at week 6. CONCLUSION: This data suggests that the clinical effectiveness of the 1,450-nm diode laser may be based, at least in part, on its effects on sebaceous glands, with subsequent reduction in sebum production. SN - 0196-8092 UR - https://www.unboundmedicine.com/medline/citation/17311272/The_1450_nm_diode_laser_reduces_sebum_production_in_facial_skin:_a_possible_mode_of_action_of_its_effectiveness_for_the_treatment_of_acne_vulgaris_ L2 - https://doi.org/10.1002/lsm.20465 DB - PRIME DP - Unbound Medicine ER -