Tags

Type your tag names separated by a space and hit enter

Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement.
Int J Pediatr Otorhinolaryngol 2007; 71(5):747-56IJ

Abstract

OBJECTIVE

To evaluate ciprofloxacin 0.3%/dexamethasone 0.1% (CIPRODEX, Alcon, Ft. Worth, TX) for the prevention of early post-operative otorrhea following TT placement.

METHODS

This was a single-center, randomized, evaluator-blinded, parallel-group study. Two hundred children undergoing bilateral TT placement were categorized as having unilateral ("wet/dry"), bilateral ("wet/wet"), or no ("dry/dry") effusion at the time of surgery. All patients received Ciprodex or no treatment for 5 days post-operatively and returned at 2 weeks.

RESULTS

Physician-observed otorrhea was reported in 5 (4.95%) patients receiving Ciprodex and 39 (39.39%) patients receiving no treatment (p<0.0001). Treatment decreased otorrhea in all groups, while the greatest benefit was observed in patients with bilateral effusion (93% reduction). Ciprodex treatment also decreased the rate of clinically diagnosed otitis media (OM) and effusion following TT placement (p< or =0.0006).

CONCLUSION

Ciprodex reduced early post-operative otorrhea, clinically diagnosed OM and effusion following TT insertion. The greatest reduction in otorrhea was observed in patients with bilateral effusion at the time of surgery.

Authors+Show Affiliations

CENTA Medical Group, Columbia, SC, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17316832

Citation

Giles, William, et al. "Ciprofloxacin/dexamethasone Drops Decrease the Incidence of Physician and Patient Outcomes of Otorrhea After Tube Placement." International Journal of Pediatric Otorhinolaryngology, vol. 71, no. 5, 2007, pp. 747-56.
Giles W, Dohar J, Iverson K, et al. Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement. Int J Pediatr Otorhinolaryngol. 2007;71(5):747-56.
Giles, W., Dohar, J., Iverson, K., Cockrum, P., Hill, F., & Hill, N. (2007). Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement. International Journal of Pediatric Otorhinolaryngology, 71(5), pp. 747-56.
Giles W, et al. Ciprofloxacin/dexamethasone Drops Decrease the Incidence of Physician and Patient Outcomes of Otorrhea After Tube Placement. Int J Pediatr Otorhinolaryngol. 2007;71(5):747-56. PubMed PMID: 17316832.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement. AU - Giles,William, AU - Dohar,Joseph, AU - Iverson,Kenneth, AU - Cockrum,Paul, AU - Hill,Frank, AU - Hill,Naomi, Y1 - 2007/02/20/ PY - 2006/09/20/received PY - 2007/01/09/revised PY - 2007/01/10/accepted PY - 2007/2/24/pubmed PY - 2007/7/11/medline PY - 2007/2/24/entrez SP - 747 EP - 56 JF - International journal of pediatric otorhinolaryngology JO - Int. J. Pediatr. Otorhinolaryngol. VL - 71 IS - 5 N2 - OBJECTIVE: To evaluate ciprofloxacin 0.3%/dexamethasone 0.1% (CIPRODEX, Alcon, Ft. Worth, TX) for the prevention of early post-operative otorrhea following TT placement. METHODS: This was a single-center, randomized, evaluator-blinded, parallel-group study. Two hundred children undergoing bilateral TT placement were categorized as having unilateral ("wet/dry"), bilateral ("wet/wet"), or no ("dry/dry") effusion at the time of surgery. All patients received Ciprodex or no treatment for 5 days post-operatively and returned at 2 weeks. RESULTS: Physician-observed otorrhea was reported in 5 (4.95%) patients receiving Ciprodex and 39 (39.39%) patients receiving no treatment (p<0.0001). Treatment decreased otorrhea in all groups, while the greatest benefit was observed in patients with bilateral effusion (93% reduction). Ciprodex treatment also decreased the rate of clinically diagnosed otitis media (OM) and effusion following TT placement (p< or =0.0006). CONCLUSION: Ciprodex reduced early post-operative otorrhea, clinically diagnosed OM and effusion following TT insertion. The greatest reduction in otorrhea was observed in patients with bilateral effusion at the time of surgery. SN - 0165-5876 UR - https://www.unboundmedicine.com/medline/citation/17316832/Ciprofloxacin/dexamethasone_drops_decrease_the_incidence_of_physician_and_patient_outcomes_of_otorrhea_after_tube_placement_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-5876(07)00037-7 DB - PRIME DP - Unbound Medicine ER -