Tags

Type your tag names separated by a space and hit enter

Intake of fruits, and vegetables in relation to breast cancer risk by hormone receptor status.
Breast Cancer Res Treat 2008; 107(1):113-7BC

Abstract

SUMMARY

The inconsistent associations between fruit and vegetable intake and breast cancer risk may be due to heterogeneity of associations by estrogen (ER) and progesterone receptor (PR) status of the tumors. We evaluated this hypothesis in a large (2,386 cases and 2,503 controls) population-based case-control study in Poland, conducted between 2000 and 2003. We observed significant associations between reduced overall risk of breast cancer and increasing levels of total fruit intake (odds ratio (OR) for highest versus lowest quartile = 0.76, 95%CI = 0.63-0.91; p-trend = 0.01), but not for total vegetable intake (1.13 (0.93-1.37), p-trend = 0.25), after controlling for age, energy intake and known risk factors for breast cancer. The inverse association with total fruit intake was stronger for risk of ER+ (0.69 (0.54-0.88), p-trend = 0.01) than ER- tumors (0.89 (0.67-1.19), p-trend = 0.57) (p-heterogeneity = 0.02). In conclusion, this study suggests that fruit intake might have differential associations for breast tumor subtypes defined by ER status.

Authors+Show Affiliations

Department of Cancer Epidemiology and Prevention, Cancer Center and M. Sklodowska-Curie Institute of Oncology, Warsaw, Poland. lissowsj@coi.waw.plNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17318377

Citation

Lissowska, Jolanta, et al. "Intake of Fruits, and Vegetables in Relation to Breast Cancer Risk By Hormone Receptor Status." Breast Cancer Research and Treatment, vol. 107, no. 1, 2008, pp. 113-7.
Lissowska J, Gaudet MM, Brinton LA, et al. Intake of fruits, and vegetables in relation to breast cancer risk by hormone receptor status. Breast Cancer Res Treat. 2008;107(1):113-7.
Lissowska, J., Gaudet, M. M., Brinton, L. A., Peplonska, B., Sherman, M., Szeszenia-Dabrowska, N., ... Garcia-Closas, M. (2008). Intake of fruits, and vegetables in relation to breast cancer risk by hormone receptor status. Breast Cancer Research and Treatment, 107(1), pp. 113-7.
Lissowska J, et al. Intake of Fruits, and Vegetables in Relation to Breast Cancer Risk By Hormone Receptor Status. Breast Cancer Res Treat. 2008;107(1):113-7. PubMed PMID: 17318377.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intake of fruits, and vegetables in relation to breast cancer risk by hormone receptor status. AU - Lissowska,Jolanta, AU - Gaudet,Mia M, AU - Brinton,Louise A, AU - Peplonska,Beata, AU - Sherman,Mark, AU - Szeszenia-Dabrowska,Neonila, AU - Zatonski,Witold, AU - Garcia-Closas,Montserrat, Y1 - 2007/02/21/ PY - 2007/01/12/received PY - 2007/01/16/accepted PY - 2007/2/24/pubmed PY - 2009/2/4/medline PY - 2007/2/24/entrez SP - 113 EP - 7 JF - Breast cancer research and treatment JO - Breast Cancer Res. Treat. VL - 107 IS - 1 N2 - SUMMARY: The inconsistent associations between fruit and vegetable intake and breast cancer risk may be due to heterogeneity of associations by estrogen (ER) and progesterone receptor (PR) status of the tumors. We evaluated this hypothesis in a large (2,386 cases and 2,503 controls) population-based case-control study in Poland, conducted between 2000 and 2003. We observed significant associations between reduced overall risk of breast cancer and increasing levels of total fruit intake (odds ratio (OR) for highest versus lowest quartile = 0.76, 95%CI = 0.63-0.91; p-trend = 0.01), but not for total vegetable intake (1.13 (0.93-1.37), p-trend = 0.25), after controlling for age, energy intake and known risk factors for breast cancer. The inverse association with total fruit intake was stronger for risk of ER+ (0.69 (0.54-0.88), p-trend = 0.01) than ER- tumors (0.89 (0.67-1.19), p-trend = 0.57) (p-heterogeneity = 0.02). In conclusion, this study suggests that fruit intake might have differential associations for breast tumor subtypes defined by ER status. SN - 1573-7217 UR - https://www.unboundmedicine.com/medline/citation/17318377/Intake_of_fruits_and_vegetables_in_relation_to_breast_cancer_risk_by_hormone_receptor_status_ L2 - https://doi.org/10.1007/s10549-007-9524-9 DB - PRIME DP - Unbound Medicine ER -