Tags

Type your tag names separated by a space and hit enter

Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses.
J Cataract Refract Surg. 2007 Mar; 33(3):413-7.JC

Abstract

PURPOSE

To measure posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) capsulotomy rates between the AcrySof MA30 intraocular lens (IOL) (Alcon) and the 1CU IOL (HumanOptics) in a fellow-eye comparison.

SETTING

Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom.

METHODS

Thirty patients who had bilateral cataract surgery with a 1CU IOL prospectively randomly allocated to 1 eye and an AcrySof MA30 monofocal IOL to the other eye were examined. Best corrected distance visual acuity was recorded using the Early Treatment Diabetic Retinopathy Study logMAR chart. Digital retroillumination images of the posterior capsule were taken with the pupil dilated and analyzed with POCO software.

RESULTS

Eyes with the 1CU IOL had significantly higher PCO rates than eyes with the MA30 IOL at all time points. By 2 years after surgery, 50% of eyes with a 1CU IOL had required Nd:YAG capsulotomy compared with no eyes with an MA30 IOL. There was no significant difference in visual acuity at any time point when post Nd:YAG capsulotomy was taken in to account.

CONCLUSIONS

The 1CU IOL has 4 broad optic-haptic junctions where the square-edged barrier is breached; this appeared to allow passage of lens epithelial cells, leading to an increase in PCO. However, the increased PCO cannot be attributed to this alone as the 1CU is hydrophilic, a factor known to be associated with higher PCO rates.

Authors+Show Affiliations

Hancox J
Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom.
Spalton D
No affiliation info available
Heatley C
No affiliation info available
Jayaram H
No affiliation info available
Yip J
No affiliation info available
Boyce J
No affiliation info available
Marshall J
No affiliation info available

MeSH

Accommodation, OcularAcrylic ResinsAgedCataractFemaleHumansLaser TherapyLens Capsule, CrystallineLens Implantation, IntraocularLenses, IntraocularMalePostoperative ComplicationsProspective StudiesProsthesis Design

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17321391

Citation

Hancox, Joanne, et al. "Fellow-eye Comparison of Posterior Capsule Opacification Rates After Implantation of 1CU Accommodating and AcrySof MA30 Monofocal Intraocular Lenses." Journal of Cataract and Refractive Surgery, vol. 33, no. 3, 2007, pp. 413-7.
Hancox J, Spalton D, Heatley C, et al. Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses. J Cataract Refract Surg. 2007;33(3):413-7.
Hancox, J., Spalton, D., Heatley, C., Jayaram, H., Yip, J., Boyce, J., & Marshall, J. (2007). Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses. Journal of Cataract and Refractive Surgery, 33(3), 413-7.
Hancox J, et al. Fellow-eye Comparison of Posterior Capsule Opacification Rates After Implantation of 1CU Accommodating and AcrySof MA30 Monofocal Intraocular Lenses. J Cataract Refract Surg. 2007;33(3):413-7. PubMed PMID: 17321391.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses. AU - Hancox,Joanne, AU - Spalton,David, AU - Heatley,Catherine, AU - Jayaram,Hari, AU - Yip,Jennifer, AU - Boyce,James, AU - Marshall,John, PY - 2006/04/28/received PY - 2006/10/13/accepted PY - 2007/2/27/pubmed PY - 2007/4/4/medline PY - 2007/2/27/entrez SP - 413 EP - 7 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 33 IS - 3 N2 - PURPOSE: To measure posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) capsulotomy rates between the AcrySof MA30 intraocular lens (IOL) (Alcon) and the 1CU IOL (HumanOptics) in a fellow-eye comparison. SETTING: Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom. METHODS: Thirty patients who had bilateral cataract surgery with a 1CU IOL prospectively randomly allocated to 1 eye and an AcrySof MA30 monofocal IOL to the other eye were examined. Best corrected distance visual acuity was recorded using the Early Treatment Diabetic Retinopathy Study logMAR chart. Digital retroillumination images of the posterior capsule were taken with the pupil dilated and analyzed with POCO software. RESULTS: Eyes with the 1CU IOL had significantly higher PCO rates than eyes with the MA30 IOL at all time points. By 2 years after surgery, 50% of eyes with a 1CU IOL had required Nd:YAG capsulotomy compared with no eyes with an MA30 IOL. There was no significant difference in visual acuity at any time point when post Nd:YAG capsulotomy was taken in to account. CONCLUSIONS: The 1CU IOL has 4 broad optic-haptic junctions where the square-edged barrier is breached; this appeared to allow passage of lens epithelial cells, leading to an increase in PCO. However, the increased PCO cannot be attributed to this alone as the 1CU is hydrophilic, a factor known to be associated with higher PCO rates. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/17321391/Fellow_eye_comparison_of_posterior_capsule_opacification_rates_after_implantation_of_1CU_accommodating_and_AcrySof_MA30_monofocal_intraocular_lenses_ DB - PRIME DP - Unbound Medicine ER -