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Risk factors of peripheral arterial disease and relationship between low ankle - brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with type 2 diabetes.
Circ J. 2007 Mar; 71(3):377-81.CJ

Abstract

BACKGROUND

The aim of the present study was to evaluate the risk factors for peripheral arterial disease and the relationship between the ankle - brachial index (ABI) and mortality from all-cause and cardiovascular disease (CVD) in Chinese patients with type 2 diabetes mellitus (DM).

METHODS AND RESULTS

ABI was identified at baseline by measuring systolic pressure in the bilateral brachial and tibial arteries. Mortality surveillance was completed from November 2004 to January 2006. Among 1,647 participants with type 2 DM at baseline, 531 (32.2%) were in the low-ABI group. Older age, female gender, higher serum level of total cholesterol, longer duration of DM and a history of smoking were associated with low ABI. During the 13-month follow-up, there were 132 deaths, of which 47 were from CVD. Low ABI was associated with mortality from all-cause and CVD, the adjusted relative risk of which was 1.851 (95% confidence interval 1.280-2.676) and 3.211 (1.703-6.053), respectively, in Cox regression models. The survival rate was significantly lower in the low-ABI group than in the normal-ABI group.

CONCLUSION

Low ABI was independently associated with a high risk of all-cause and CVD mortality in Chinese patients with type 2 DM. ABI should be promoted as an ideal tool for predicting mortality in diabetic patients.

Authors+Show Affiliations

Heart, Lung and Blood Vessel Center, Tongji University, Shanghai, P.R.China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17322639

Citation

Li, Jue, et al. "Risk Factors of Peripheral Arterial Disease and Relationship Between Low Ankle - Brachial Index and Mortality From All-cause and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes." Circulation Journal : Official Journal of the Japanese Circulation Society, vol. 71, no. 3, 2007, pp. 377-81.
Li J, Luo Y, Xu Y, et al. Risk factors of peripheral arterial disease and relationship between low ankle - brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with type 2 diabetes. Circ J. 2007;71(3):377-81.
Li, J., Luo, Y., Xu, Y., Yang, J., Zheng, L., Hasimu, B., Yu, J., & Hu, D. (2007). Risk factors of peripheral arterial disease and relationship between low ankle - brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with type 2 diabetes. Circulation Journal : Official Journal of the Japanese Circulation Society, 71(3), 377-81.
Li J, et al. Risk Factors of Peripheral Arterial Disease and Relationship Between Low Ankle - Brachial Index and Mortality From All-cause and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes. Circ J. 2007;71(3):377-81. PubMed PMID: 17322639.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors of peripheral arterial disease and relationship between low ankle - brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with type 2 diabetes. AU - Li,Jue, AU - Luo,Yingyi, AU - Xu,Yawei, AU - Yang,Jingang, AU - Zheng,Liqiang, AU - Hasimu,Buaijiaer, AU - Yu,Jinming, AU - Hu,Dayi, PY - 2007/2/27/pubmed PY - 2007/5/8/medline PY - 2007/2/27/entrez SP - 377 EP - 81 JF - Circulation journal : official journal of the Japanese Circulation Society JO - Circ J VL - 71 IS - 3 N2 - BACKGROUND: The aim of the present study was to evaluate the risk factors for peripheral arterial disease and the relationship between the ankle - brachial index (ABI) and mortality from all-cause and cardiovascular disease (CVD) in Chinese patients with type 2 diabetes mellitus (DM). METHODS AND RESULTS: ABI was identified at baseline by measuring systolic pressure in the bilateral brachial and tibial arteries. Mortality surveillance was completed from November 2004 to January 2006. Among 1,647 participants with type 2 DM at baseline, 531 (32.2%) were in the low-ABI group. Older age, female gender, higher serum level of total cholesterol, longer duration of DM and a history of smoking were associated with low ABI. During the 13-month follow-up, there were 132 deaths, of which 47 were from CVD. Low ABI was associated with mortality from all-cause and CVD, the adjusted relative risk of which was 1.851 (95% confidence interval 1.280-2.676) and 3.211 (1.703-6.053), respectively, in Cox regression models. The survival rate was significantly lower in the low-ABI group than in the normal-ABI group. CONCLUSION: Low ABI was independently associated with a high risk of all-cause and CVD mortality in Chinese patients with type 2 DM. ABI should be promoted as an ideal tool for predicting mortality in diabetic patients. SN - 1346-9843 UR - https://www.unboundmedicine.com/medline/citation/17322639/Risk_factors_of_peripheral_arterial_disease_and_relationship_between_low_ankle___brachial_index_and_mortality_from_all_cause_and_cardiovascular_disease_in_Chinese_patients_with_type_2_diabetes_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/circj/71.377?from=PubMed DB - PRIME DP - Unbound Medicine ER -