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Blood pressure parameters and risk of fatal stroke, NHANES II mortality study.
Am J Hypertens. 2007 Mar; 20(3):338-41.AJ

Abstract

BACKGROUND

Recent studies have suggested that systolic blood pressure (BP) is a better predictor of stroke than diastolic BP in apparently healthy white men. Whether these relationships are similar for women and African Americans remains unclear.

METHODS

We used data from 6667 (3205 men; 3462 women) adults from the Second National Health and Nutrition Examination Survey Mortality Study to examine whether the relative risk of fatal stroke was associated with a 10 mm Hg increase in BP parameters (systolic BP, diastolic BP, pulse pressure, and mean arterial pressure).

RESULTS

During a median of nearly 15 years of follow-up, 113 fatal strokes (62 men; 51 women) occurred. Systolic BP was associated with an increased risk of fatal stroke for men (relative risk [RR] = 1.19), women (RR = 1.15), whites (RR = 1.17), and African Americans (RR = 1.28) after multivariable adjustment (all, P </= .05). Results for other BP parameters were not consistent; simultaneous consideration of two parameters did not improve prediction of fatal stroke over systolic BP alone.

CONCLUSIONS

Our results agree with previous studies that indicate systolic BP is an important predictor of stroke risk for all groups within the population and provide further evidence of the need to control systolic BP in the population.

Authors+Show Affiliations

Centers for Disease Control and Prevention, Atlanta, Georgia, USA. dbrown6@cdc.govNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17324749

Citation

Brown, David W., et al. "Blood Pressure Parameters and Risk of Fatal Stroke, NHANES II Mortality Study." American Journal of Hypertension, vol. 20, no. 3, 2007, pp. 338-41.
Brown DW, Giles WH, Greenlund KJ. Blood pressure parameters and risk of fatal stroke, NHANES II mortality study. Am J Hypertens. 2007;20(3):338-41.
Brown, D. W., Giles, W. H., & Greenlund, K. J. (2007). Blood pressure parameters and risk of fatal stroke, NHANES II mortality study. American Journal of Hypertension, 20(3), 338-41.
Brown DW, Giles WH, Greenlund KJ. Blood Pressure Parameters and Risk of Fatal Stroke, NHANES II Mortality Study. Am J Hypertens. 2007;20(3):338-41. PubMed PMID: 17324749.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Blood pressure parameters and risk of fatal stroke, NHANES II mortality study. AU - Brown,David W, AU - Giles,Wayne H, AU - Greenlund,Kurt J, PY - 2006/06/06/received PY - 2006/07/12/revised PY - 2006/08/04/accepted PY - 2007/2/28/pubmed PY - 2007/4/21/medline PY - 2007/2/28/entrez SP - 338 EP - 41 JF - American journal of hypertension JO - Am J Hypertens VL - 20 IS - 3 N2 - BACKGROUND: Recent studies have suggested that systolic blood pressure (BP) is a better predictor of stroke than diastolic BP in apparently healthy white men. Whether these relationships are similar for women and African Americans remains unclear. METHODS: We used data from 6667 (3205 men; 3462 women) adults from the Second National Health and Nutrition Examination Survey Mortality Study to examine whether the relative risk of fatal stroke was associated with a 10 mm Hg increase in BP parameters (systolic BP, diastolic BP, pulse pressure, and mean arterial pressure). RESULTS: During a median of nearly 15 years of follow-up, 113 fatal strokes (62 men; 51 women) occurred. Systolic BP was associated with an increased risk of fatal stroke for men (relative risk [RR] = 1.19), women (RR = 1.15), whites (RR = 1.17), and African Americans (RR = 1.28) after multivariable adjustment (all, P </= .05). Results for other BP parameters were not consistent; simultaneous consideration of two parameters did not improve prediction of fatal stroke over systolic BP alone. CONCLUSIONS: Our results agree with previous studies that indicate systolic BP is an important predictor of stroke risk for all groups within the population and provide further evidence of the need to control systolic BP in the population. SN - 0895-7061 UR - https://www.unboundmedicine.com/medline/citation/17324749/Blood_pressure_parameters_and_risk_of_fatal_stroke_NHANES_II_mortality_study_ L2 - https://academic.oup.com/ajh/article-lookup/doi/10.1016/j.amjhyper.2006.08.004 DB - PRIME DP - Unbound Medicine ER -