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Does selective vagotomy prevent delayed gastric emptying and altered myoelectric activity following Roux-en-Y gastrojejunostomy?
Am J Surg. 1992 Jan; 163(1):32-5; discussion 35-6.AJ

Abstract

Delayed gastric emptying occurs frequently following Roux-en-Y gastrojejunostomy. The role of vagal denervation in the etiology of this "Roux-stasis syndrome" is controversial. This study evaluates the effect of selective vagotomy on gastric emptying and motility following Roux-en-Y. Four dogs underwent control gastric emptying studies. The animals then underwent selective vagotomy, antrectomy, and Billroth II gastrojejunostomy, with placement of serosal electrodes. Gastric emptying was assessed with simultaneous myoelectric recordings, and the animals were converted to Roux-en-Y, followed by repeat studies. Gastric emptying was unchanged following selective vagotomy, antrectomy, and Billroth II gastrojejunostomy (T 1/2: 132 +/- 18 min [SEM] versus 118 +/- 14 min control) but was markedly delayed following Roux-en-Y diversion (T 1/2: 286 +/- 44 min; p less than 0.01). All animals went into the fed pattern following Billroth II gastrojejunostomy (migrating myoelectric complex [MMC] interval: 326 +/- 6 min postprandial versus 92 +/- 5 min fasting; p less than 0.01), but no fed pattern was recognized in three of four animals following Roux-en-Y diversion (MMC interval: 68 +/- 12 min postprandial versus 62 +/- 1.5 min fasting; p = NS). In a canine model, selective vagotomy does not prevent delayed gastric emptying or myoelectric alterations following Roux-en-Y.

Authors+Show Affiliations

Department of Surgery, University of Florida College of Medicine, Gainesville.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

1733372

Citation

Hocking, M P., et al. "Does Selective Vagotomy Prevent Delayed Gastric Emptying and Altered Myoelectric Activity Following Roux-en-Y Gastrojejunostomy?" American Journal of Surgery, vol. 163, no. 1, 1992, pp. 32-5; discussion 35-6.
Hocking MP, Carlson RG, Vogel SB. Does selective vagotomy prevent delayed gastric emptying and altered myoelectric activity following Roux-en-Y gastrojejunostomy? Am J Surg. 1992;163(1):32-5; discussion 35-6.
Hocking, M. P., Carlson, R. G., & Vogel, S. B. (1992). Does selective vagotomy prevent delayed gastric emptying and altered myoelectric activity following Roux-en-Y gastrojejunostomy? American Journal of Surgery, 163(1), 32-5; discussion 35-6.
Hocking MP, Carlson RG, Vogel SB. Does Selective Vagotomy Prevent Delayed Gastric Emptying and Altered Myoelectric Activity Following Roux-en-Y Gastrojejunostomy. Am J Surg. 1992;163(1):32-5; discussion 35-6. PubMed PMID: 1733372.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does selective vagotomy prevent delayed gastric emptying and altered myoelectric activity following Roux-en-Y gastrojejunostomy? AU - Hocking,M P, AU - Carlson,R G, AU - Vogel,S B, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 32-5; discussion 35-6 JF - American journal of surgery JO - Am J Surg VL - 163 IS - 1 N2 - Delayed gastric emptying occurs frequently following Roux-en-Y gastrojejunostomy. The role of vagal denervation in the etiology of this "Roux-stasis syndrome" is controversial. This study evaluates the effect of selective vagotomy on gastric emptying and motility following Roux-en-Y. Four dogs underwent control gastric emptying studies. The animals then underwent selective vagotomy, antrectomy, and Billroth II gastrojejunostomy, with placement of serosal electrodes. Gastric emptying was assessed with simultaneous myoelectric recordings, and the animals were converted to Roux-en-Y, followed by repeat studies. Gastric emptying was unchanged following selective vagotomy, antrectomy, and Billroth II gastrojejunostomy (T 1/2: 132 +/- 18 min [SEM] versus 118 +/- 14 min control) but was markedly delayed following Roux-en-Y diversion (T 1/2: 286 +/- 44 min; p less than 0.01). All animals went into the fed pattern following Billroth II gastrojejunostomy (migrating myoelectric complex [MMC] interval: 326 +/- 6 min postprandial versus 92 +/- 5 min fasting; p less than 0.01), but no fed pattern was recognized in three of four animals following Roux-en-Y diversion (MMC interval: 68 +/- 12 min postprandial versus 62 +/- 1.5 min fasting; p = NS). In a canine model, selective vagotomy does not prevent delayed gastric emptying or myoelectric alterations following Roux-en-Y. SN - 0002-9610 UR - https://www.unboundmedicine.com/medline/citation/1733372/Does_selective_vagotomy_prevent_delayed_gastric_emptying_and_altered_myoelectric_activity_following_Roux_en_Y_gastrojejunostomy L2 - https://linkinghub.elsevier.com/retrieve/pii/0002-9610(92)90249-Q DB - PRIME DP - Unbound Medicine ER -