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Cutaneous vascular alterations in psoriatic patients treated with cyclosporine.
Acta Derm Venereol. 2007; 87(2):152-4.AD

Abstract

Videocapillaroscopy can be used to assess cutaneous microcirculation modifications in vivo, and therefore allows assessment of variations in the microvascular architecture in psoriatic subjects during treatment. The aim of this study was to observe and quantify the modifications of the superficial capillary bed in psoriatic plaques during treatment with cyclosporin A. Twelve patients with psoriasis vulgaris were treated with an initial dose of 4 mg/kg/day cyclosporin A over a period of 3 months with periodic clinical and capillaroscopic assessments. Clinical resolution of the lesions and a reduction in microcirculatory alterations was observed in 70% of patients, although none returned to a normal capillaroscopic pattern.

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Authors+Show Affiliations

Stinco G
Institute of Dermatology, Department of Clinical and Experimental Pathology and Medicine, University of Udine School of Medicine, Udine, Italy. giuseppe.stinco@uniud.it
Lautieri S
No affiliation info available
Valent F
No affiliation info available
Patrone P
No affiliation info available

MeSH

AdultAgedAged, 80 and overCyclosporineFemaleHumansMaleMicrocirculationMicroscopic AngioscopyMiddle AgedPsoriasisSkin

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

17340023

Citation

Stinco, Giuseppe, et al. "Cutaneous Vascular Alterations in Psoriatic Patients Treated With Cyclosporine." Acta Dermato-venereologica, vol. 87, no. 2, 2007, pp. 152-4.
Stinco G, Lautieri S, Valent F, et al. Cutaneous vascular alterations in psoriatic patients treated with cyclosporine. Acta Derm Venereol. 2007;87(2):152-4.
Stinco, G., Lautieri, S., Valent, F., & Patrone, P. (2007). Cutaneous vascular alterations in psoriatic patients treated with cyclosporine. Acta Dermato-venereologica, 87(2), 152-4.
Stinco G, et al. Cutaneous Vascular Alterations in Psoriatic Patients Treated With Cyclosporine. Acta Derm Venereol. 2007;87(2):152-4. PubMed PMID: 17340023.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cutaneous vascular alterations in psoriatic patients treated with cyclosporine. AU - Stinco,Giuseppe, AU - Lautieri,Stefano, AU - Valent,Francesca, AU - Patrone,Pasquale, PY - 2007/3/7/pubmed PY - 2007/8/10/medline PY - 2007/3/7/entrez SP - 152 EP - 4 JF - Acta dermato-venereologica JO - Acta Derm Venereol VL - 87 IS - 2 N2 - Videocapillaroscopy can be used to assess cutaneous microcirculation modifications in vivo, and therefore allows assessment of variations in the microvascular architecture in psoriatic subjects during treatment. The aim of this study was to observe and quantify the modifications of the superficial capillary bed in psoriatic plaques during treatment with cyclosporin A. Twelve patients with psoriasis vulgaris were treated with an initial dose of 4 mg/kg/day cyclosporin A over a period of 3 months with periodic clinical and capillaroscopic assessments. Clinical resolution of the lesions and a reduction in microcirculatory alterations was observed in 70% of patients, although none returned to a normal capillaroscopic pattern. SN - 0001-5555 UR - https://www.unboundmedicine.com/medline/citation/17340023/Cutaneous_vascular_alterations_in_psoriatic_patients_treated_with_cyclosporine_ L2 - https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-0216 DB - PRIME DP - Unbound Medicine ER -