Tags

Type your tag names separated by a space and hit enter

Treatment of lymphogranuloma venereum.
Clin Infect Dis. 2007 Apr 01; 44 Suppl 3:S147-52.CI

Abstract

BACKGROUND

Lymphogranuloma venereum (LGV) classically presents with 1 or more genital ulcers or papules, as well as inguinal lymphadenopathy (buboes). Recently reported cases of LGV proctitis in men who have sex with men, many of whom are coinfected with human immunodeficiency virus (HIV), have highlighted the importance of optimal clinical treatment of LGV.

METHODS

A review was conducted of the literature on LGV published between 1998 and 2004, as part of the development of the 2006 sexually transmitted disease treatment guidelines of the Centers for Disease Control and Prevention (CDC).

RESULTS

Doxycycline (100 mg orally twice daily for 21 days) remains the treatment of choice for LGV. No controlled trials support the use of azithromycin or the use of alternative treatment regimens for persons with HIV infection.

CONCLUSIONS

On the basis of the present literature review, the CDC's treatment recommendations for LGV remain unchanged. LGV clinical care, surveillance, and research are severely hindered by the lack of widely available, rapid, standardized tests for the diagnosis of LGV; therefore, patients with symptoms suggestive of LGV, including LGV proctitis, should be presumptively treated with antibacterial therapy for 3 weeks.

Authors+Show Affiliations

Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention (proposed), Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. CMcLean@cdc.govNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

17342667

Citation

McLean, Catherine A., et al. "Treatment of Lymphogranuloma Venereum." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 44 Suppl 3, 2007, pp. S147-52.
McLean CA, Stoner BP, Workowski KA. Treatment of lymphogranuloma venereum. Clin Infect Dis. 2007;44 Suppl 3:S147-52.
McLean, C. A., Stoner, B. P., & Workowski, K. A. (2007). Treatment of lymphogranuloma venereum. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 44 Suppl 3, S147-52.
McLean CA, Stoner BP, Workowski KA. Treatment of Lymphogranuloma Venereum. Clin Infect Dis. 2007 Apr 1;44 Suppl 3:S147-52. PubMed PMID: 17342667.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of lymphogranuloma venereum. AU - McLean,Catherine A, AU - Stoner,Bradley P, AU - Workowski,Kimberly A, PY - 2007/3/8/pubmed PY - 2007/8/10/medline PY - 2007/3/8/entrez SP - S147 EP - 52 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin. Infect. Dis. VL - 44 Suppl 3 N2 - BACKGROUND: Lymphogranuloma venereum (LGV) classically presents with 1 or more genital ulcers or papules, as well as inguinal lymphadenopathy (buboes). Recently reported cases of LGV proctitis in men who have sex with men, many of whom are coinfected with human immunodeficiency virus (HIV), have highlighted the importance of optimal clinical treatment of LGV. METHODS: A review was conducted of the literature on LGV published between 1998 and 2004, as part of the development of the 2006 sexually transmitted disease treatment guidelines of the Centers for Disease Control and Prevention (CDC). RESULTS: Doxycycline (100 mg orally twice daily for 21 days) remains the treatment of choice for LGV. No controlled trials support the use of azithromycin or the use of alternative treatment regimens for persons with HIV infection. CONCLUSIONS: On the basis of the present literature review, the CDC's treatment recommendations for LGV remain unchanged. LGV clinical care, surveillance, and research are severely hindered by the lack of widely available, rapid, standardized tests for the diagnosis of LGV; therefore, patients with symptoms suggestive of LGV, including LGV proctitis, should be presumptively treated with antibacterial therapy for 3 weeks. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/17342667/Treatment_of_lymphogranuloma_venereum_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/511427 DB - PRIME DP - Unbound Medicine ER -