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Risk factors of peripheral arterial disease and relationship between low ankle brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with hypertension.
J Hum Hypertens. 2007 Jun; 21(6):461-6.JH

Abstract

The aim of this study was to evaluate the risk factors of peripheral arterial disease (PAD) and the relationship between ankle brachial index (ABI) and mortality from all-cause and cardiovascular disease (CVD) in Chinese patients with hypertension. The ABI cohort Study was designed to investigate risk factors of PAD and the relationship between ABI and mortality from all-cause and CVD in Chinese patients. ABI was identified at baseline by measuring systolic pressure at bilateral brachial and tibial arteries. Mortality surveillance was completed from November 2005 to January 2006. Among 3047 participants with hypertension at baseline, 839 (27.5%) were in the low-ABI group. Older age, female gender, higher serum level of triglycerides, lower serum level of high-density lipoprotein, a history of diabetes and a history of smoking were associated with low ABI. During the 13-month follow-up, there were 252 deaths, of which 100 died of CVD. Low ABI was associated with mortality from all-cause and CVD, whose adjusted relative risk was 1.619 (95% confidence interval 1.190-2.203) and 2.454 (1.531-3.933), respectively, in Cox regression models. The survival rate was significantly lower in the low-ABI group than in the normal-ABI group. This study demonstrated that low ABI was independently associated with a high risk of all-cause and CVD mortality in Chinese patients with hypertension. ABI should be promoted as an ideal tool to predict mortality in diabetic patients.

Authors+Show Affiliations

Heart, Lung and Blood Vessel Center, Tongji University, Shanghai, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17344909

Citation

Luo, Y Y., et al. "Risk Factors of Peripheral Arterial Disease and Relationship Between Low Ankle Brachial Index and Mortality From All-cause and Cardiovascular Disease in Chinese Patients With Hypertension." Journal of Human Hypertension, vol. 21, no. 6, 2007, pp. 461-6.
Luo YY, Li J, Xin Y, et al. Risk factors of peripheral arterial disease and relationship between low ankle brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with hypertension. J Hum Hypertens. 2007;21(6):461-6.
Luo, Y. Y., Li, J., Xin, Y., Zheng, L. Q., Yu, J. M., & Hu, D. Y. (2007). Risk factors of peripheral arterial disease and relationship between low ankle brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with hypertension. Journal of Human Hypertension, 21(6), 461-6.
Luo YY, et al. Risk Factors of Peripheral Arterial Disease and Relationship Between Low Ankle Brachial Index and Mortality From All-cause and Cardiovascular Disease in Chinese Patients With Hypertension. J Hum Hypertens. 2007;21(6):461-6. PubMed PMID: 17344909.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors of peripheral arterial disease and relationship between low ankle brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with hypertension. AU - Luo,Y Y, AU - Li,J, AU - Xin,Y, AU - Zheng,L Q, AU - Yu,J M, AU - Hu,D Y, Y1 - 2007/03/08/ PY - 2007/3/9/pubmed PY - 2007/10/30/medline PY - 2007/3/9/entrez SP - 461 EP - 6 JF - Journal of human hypertension JO - J Hum Hypertens VL - 21 IS - 6 N2 - The aim of this study was to evaluate the risk factors of peripheral arterial disease (PAD) and the relationship between ankle brachial index (ABI) and mortality from all-cause and cardiovascular disease (CVD) in Chinese patients with hypertension. The ABI cohort Study was designed to investigate risk factors of PAD and the relationship between ABI and mortality from all-cause and CVD in Chinese patients. ABI was identified at baseline by measuring systolic pressure at bilateral brachial and tibial arteries. Mortality surveillance was completed from November 2005 to January 2006. Among 3047 participants with hypertension at baseline, 839 (27.5%) were in the low-ABI group. Older age, female gender, higher serum level of triglycerides, lower serum level of high-density lipoprotein, a history of diabetes and a history of smoking were associated with low ABI. During the 13-month follow-up, there were 252 deaths, of which 100 died of CVD. Low ABI was associated with mortality from all-cause and CVD, whose adjusted relative risk was 1.619 (95% confidence interval 1.190-2.203) and 2.454 (1.531-3.933), respectively, in Cox regression models. The survival rate was significantly lower in the low-ABI group than in the normal-ABI group. This study demonstrated that low ABI was independently associated with a high risk of all-cause and CVD mortality in Chinese patients with hypertension. ABI should be promoted as an ideal tool to predict mortality in diabetic patients. SN - 0950-9240 UR - https://www.unboundmedicine.com/medline/citation/17344909/Risk_factors_of_peripheral_arterial_disease_and_relationship_between_low_ankle_brachial_index_and_mortality_from_all_cause_and_cardiovascular_disease_in_Chinese_patients_with_hypertension_ L2 - https://doi.org/10.1038/sj.jhh.1002177 DB - PRIME DP - Unbound Medicine ER -