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Peri-operative morbidity and early results of a randomised trial comparing TVT and TVT-O.
Int Urogynecol J Pelvic Floor Dysfunct. 2007 Nov; 18(11):1257-61.IU

Abstract

The aim of this study was to compare the morbidity and short-term efficacy of retro-pubic (TVT) and inside-out trans-obturator (TVT-O) sub-urethral sling in the treatment of stress urinary incontinence. This was a prospective multi-centre randomised trial; 231 women with primary stress urinary incontinence were randomised to TVT (114) or TVT-O (117). The International Consultation on Incontinence-Short Form (ICIQ-SF), Women Irritative Prostate Symptoms Score (W-IPSS) and Patient Global Impression of Severity (PGI-S) questionnaires were used to evaluate the impact of incontinence and voiding dysfunction on QoL and to measure the patient's perception of incontinence severity. The primary and secondary outcome measures were rates of success and complications. The SPSS software was used for data analysis. The TVT-O procedure was associated with significantly shorter operation time and with a more extensive use of general anaesthesia when compared with TVT. There were 5 (4%) bladder perforations in the TVT group compared with none in the TVT-O group. Rates of early post-operative urinary retention and voiding difficulty were similar for both groups and no difference was found in the average hospital stay. Six patients (5%) in the TVT-O group complained of thigh pain in the post-operative course. The median follow-up time was 6 months. Two hundred eighteen patients were available for the analysis of outcomes. Subjective and objective cure rates were 92% and 92% in the TVT group and 87% and 89% in the TVT-O group. The ICIQ-SF questionnaire symptoms score showed a highly statistical decrease in both groups, the W-IPSS on the contrary was unchanged. Our data show that both procedures were equally effective in the short-term for the treatment of stress urinary incontinence with a highly significant improvement in incontinence-related QoL.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Ospedale G. Fornaroli, Magenta, Italy. m.meschia@libero.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Randomized Controlled Trial

Language

eng

PubMed ID

17345002

Citation

Meschia, Michele, et al. "Peri-operative Morbidity and Early Results of a Randomised Trial Comparing TVT and TVT-O." International Urogynecology Journal and Pelvic Floor Dysfunction, vol. 18, no. 11, 2007, pp. 1257-61.
Meschia M, Bertozzi R, Pifarotti P, et al. Peri-operative morbidity and early results of a randomised trial comparing TVT and TVT-O. Int Urogynecol J Pelvic Floor Dysfunct. 2007;18(11):1257-61.
Meschia, M., Bertozzi, R., Pifarotti, P., Baccichet, R., Bernasconi, F., Guercio, E., Magatti, F., & Minini, G. (2007). Peri-operative morbidity and early results of a randomised trial comparing TVT and TVT-O. International Urogynecology Journal and Pelvic Floor Dysfunction, 18(11), 1257-61.
Meschia M, et al. Peri-operative Morbidity and Early Results of a Randomised Trial Comparing TVT and TVT-O. Int Urogynecol J Pelvic Floor Dysfunct. 2007;18(11):1257-61. PubMed PMID: 17345002.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Peri-operative morbidity and early results of a randomised trial comparing TVT and TVT-O. AU - Meschia,Michele, AU - Bertozzi,Rosanna, AU - Pifarotti,Paola, AU - Baccichet,Roberto, AU - Bernasconi,Francesco, AU - Guercio,Elso, AU - Magatti,Fabio, AU - Minini,Gianfranco, Y1 - 2007/03/08/ PY - 2006/10/11/received PY - 2007/02/12/accepted PY - 2007/3/9/pubmed PY - 2008/1/12/medline PY - 2007/3/9/entrez SP - 1257 EP - 61 JF - International urogynecology journal and pelvic floor dysfunction JO - Int Urogynecol J Pelvic Floor Dysfunct VL - 18 IS - 11 N2 - The aim of this study was to compare the morbidity and short-term efficacy of retro-pubic (TVT) and inside-out trans-obturator (TVT-O) sub-urethral sling in the treatment of stress urinary incontinence. This was a prospective multi-centre randomised trial; 231 women with primary stress urinary incontinence were randomised to TVT (114) or TVT-O (117). The International Consultation on Incontinence-Short Form (ICIQ-SF), Women Irritative Prostate Symptoms Score (W-IPSS) and Patient Global Impression of Severity (PGI-S) questionnaires were used to evaluate the impact of incontinence and voiding dysfunction on QoL and to measure the patient's perception of incontinence severity. The primary and secondary outcome measures were rates of success and complications. The SPSS software was used for data analysis. The TVT-O procedure was associated with significantly shorter operation time and with a more extensive use of general anaesthesia when compared with TVT. There were 5 (4%) bladder perforations in the TVT group compared with none in the TVT-O group. Rates of early post-operative urinary retention and voiding difficulty were similar for both groups and no difference was found in the average hospital stay. Six patients (5%) in the TVT-O group complained of thigh pain in the post-operative course. The median follow-up time was 6 months. Two hundred eighteen patients were available for the analysis of outcomes. Subjective and objective cure rates were 92% and 92% in the TVT group and 87% and 89% in the TVT-O group. The ICIQ-SF questionnaire symptoms score showed a highly statistical decrease in both groups, the W-IPSS on the contrary was unchanged. Our data show that both procedures were equally effective in the short-term for the treatment of stress urinary incontinence with a highly significant improvement in incontinence-related QoL. UR - https://www.unboundmedicine.com/medline/citation/17345002/Peri_operative_morbidity_and_early_results_of_a_randomised_trial_comparing_TVT_and_TVT_O_ L2 - https://medlineplus.gov/pelvicfloordisorders.html DB - PRIME DP - Unbound Medicine ER -