An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air.
Org Lett. 2007 Mar 29; 9(7):1407-9.OL

Abstract

[structure: see text]. The direct oxidative coupling of benzoic acids with internal alkynes proceeds efficiently in the presence of a rhodium/copper catalyst system under air to afford the corresponding isocoumarin derivatives. The reaction forms no wastes except for water. Under similar conditions, the aerobic coupling with acrylates also takes place smoothly to produce 7-vinylphthalide derivatives via divinylation and subsequent cyclization.

Authors+Show Affiliations

Ueura K

Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka, Japan.

Satoh T

No affiliation info available

Miura M

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17346060

Citation

Ueura, Kenji, et al. "An Efficient Waste-free Oxidative Coupling Via Regioselective C-H Bond Cleavage: Rh/Cu-catalyzed Reaction of Benzoic Acids With Alkynes and Acrylates Under Air." Organic Letters, vol. 9, no. 7, 2007, pp. 1407-9.

Ueura K, Satoh T, Miura M. An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air. Org Lett. 2007;9(7):1407-9.

Ueura, K., Satoh, T., & Miura, M. (2007). An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air. Organic Letters, 9(7), 1407-9.

Ueura K, Satoh T, Miura M. An Efficient Waste-free Oxidative Coupling Via Regioselective C-H Bond Cleavage: Rh/Cu-catalyzed Reaction of Benzoic Acids With Alkynes and Acrylates Under Air. Org Lett. 2007 Mar 29;9(7):1407-9. PubMed PMID: 17346060.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air. AU - Ueura,Kenji, AU - Satoh,Tetsuya, AU - Miura,Masahiro, Y1 - 2007/03/09/ PY - 2007/3/10/pubmed PY - 2007/3/10/medline PY - 2007/3/10/entrez SP - 1407 EP - 9 JF - Organic letters JO - Org Lett VL - 9 IS - 7 N2 - [structure: see text]. The direct oxidative coupling of benzoic acids with internal alkynes proceeds efficiently in the presence of a rhodium/copper catalyst system under air to afford the corresponding isocoumarin derivatives. The reaction forms no wastes except for water. Under similar conditions, the aerobic coupling with acrylates also takes place smoothly to produce 7-vinylphthalide derivatives via divinylation and subsequent cyclization. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/17346060/An_efficient_waste_free_oxidative_coupling_via_regioselective_C_H_bond_cleavage:_Rh/Cu_catalyzed_reaction_of_benzoic_acids_with_alkynes_and_acrylates_under_air_ DB - PRIME DP - Unbound Medicine ER -

Tags

An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air.Org Lett. 2007 Mar 29; 9(7):1407-9.OL