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A new alcohol provocation head up tilt protocol in the patients with alcohol-related syncope.
Europace. 2007 Apr; 9(4):220-4.E

Abstract

AIMS

Drinking alcohol is known to be one of the triggering factors of neurally-mediated syncope. Little is known about the diagnostic utility of the conventional and alcohol provocation head up tilt-test (HUT) in patients with alcohol-related syncope. We investigated the effect of the alcohol provocation HUT.

METHODS AND RESULTS

We studied 12 patients (8 males, age 51 +/- 19 years) who had a history of unexplained post-alcohol ingestion syncope. An alcohol provocation protocol HUT (alcohol HUT), in which the protocol required 350 mL of 5% alcohol beer to be drunk over 5 min followed by positioning with the table tilted up for up to 30 min, was performed after the control and isoproterenol (ISP) HUT. None of the subjects (0/12) exhibited a positive response in the control HUT, and only one subject had a positive response (1/12; 8.3%) in the ISP HUT. In the alcohol HUT a positive response (9/12; 75%) increased in the patient group, whereas there were no positive responses in the normal control group.

CONCLUSION

In the conventional HUT protocols, including ISP provocation, it was difficult to produce a positive response in the patients with alcohol-related syncope. Alcohol ingestion was a useful diagnostic provocation method in such patients.

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Authors+Show Affiliations

Tateoka K
Department of Internal Medicine, Division of Cardiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 1138603, Japan.
Iwasaki YK
No affiliation info available
Ono T
No affiliation info available
Kobayashi Y
No affiliation info available
Katoh T
No affiliation info available
Takano T
No affiliation info available

MeSH

Alcohol DrinkingEthanolFemaleHumansMaleMiddle AgedReproducibility of ResultsSensitivity and SpecificitySyncopeTilt-Table Test

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17347329

Citation

Tateoka, Katsuhiko, et al. "A New Alcohol Provocation Head Up Tilt Protocol in the Patients With Alcohol-related Syncope." Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, vol. 9, no. 4, 2007, pp. 220-4.
Tateoka K, Iwasaki YK, Ono T, et al. A new alcohol provocation head up tilt protocol in the patients with alcohol-related syncope. Europace. 2007;9(4):220-4.
Tateoka, K., Iwasaki, Y. K., Ono, T., Kobayashi, Y., Katoh, T., & Takano, T. (2007). A new alcohol provocation head up tilt protocol in the patients with alcohol-related syncope. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, 9(4), 220-4.
Tateoka K, et al. A New Alcohol Provocation Head Up Tilt Protocol in the Patients With Alcohol-related Syncope. Europace. 2007;9(4):220-4. PubMed PMID: 17347329.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new alcohol provocation head up tilt protocol in the patients with alcohol-related syncope. AU - Tateoka,Katsuhiko, AU - Iwasaki,Yu-ki, AU - Ono,Takuya, AU - Kobayashi,Yoshinori, AU - Katoh,Takao, AU - Takano,Teruo, Y1 - 2007/03/08/ PY - 2007/3/10/pubmed PY - 2007/6/20/medline PY - 2007/3/10/entrez SP - 220 EP - 4 JF - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology JO - Europace VL - 9 IS - 4 N2 - AIMS: Drinking alcohol is known to be one of the triggering factors of neurally-mediated syncope. Little is known about the diagnostic utility of the conventional and alcohol provocation head up tilt-test (HUT) in patients with alcohol-related syncope. We investigated the effect of the alcohol provocation HUT. METHODS AND RESULTS: We studied 12 patients (8 males, age 51 +/- 19 years) who had a history of unexplained post-alcohol ingestion syncope. An alcohol provocation protocol HUT (alcohol HUT), in which the protocol required 350 mL of 5% alcohol beer to be drunk over 5 min followed by positioning with the table tilted up for up to 30 min, was performed after the control and isoproterenol (ISP) HUT. None of the subjects (0/12) exhibited a positive response in the control HUT, and only one subject had a positive response (1/12; 8.3%) in the ISP HUT. In the alcohol HUT a positive response (9/12; 75%) increased in the patient group, whereas there were no positive responses in the normal control group. CONCLUSION: In the conventional HUT protocols, including ISP provocation, it was difficult to produce a positive response in the patients with alcohol-related syncope. Alcohol ingestion was a useful diagnostic provocation method in such patients. SN - 1099-5129 UR - https://www.unboundmedicine.com/medline/citation/17347329/A_new_alcohol_provocation_head_up_tilt_protocol_in_the_patients_with_alcohol_related_syncope_ L2 - https://academic.oup.com/europace/article-lookup/doi/10.1093/europace/eum025 DB - PRIME DP - Unbound Medicine ER -