Citation
Mollet, Nico R., et al. "Adjunctive Value of CT Coronary Angiography in the Diagnostic Work-up of Patients With Typical Angina Pectoris." European Heart Journal, vol. 28, no. 15, 2007, pp. 1872-8.
Mollet NR, Cademartiri F, Van Mieghem C, et al. Adjunctive value of CT coronary angiography in the diagnostic work-up of patients with typical angina pectoris. Eur Heart J. 2007;28(15):1872-8.
Mollet, N. R., Cademartiri, F., Van Mieghem, C., Meijboom, B., Pugliese, F., Runza, G., Baks, T., Dikkeboer, J., McFadden, E. P., Freericks, M. P., Kerker, J. P., Zoet, S. K., Boersma, E., Krestin, G. P., & de Feyter, P. J. (2007). Adjunctive value of CT coronary angiography in the diagnostic work-up of patients with typical angina pectoris. European Heart Journal, 28(15), 1872-8.
Mollet NR, et al. Adjunctive Value of CT Coronary Angiography in the Diagnostic Work-up of Patients With Typical Angina Pectoris. Eur Heart J. 2007;28(15):1872-8. PubMed PMID: 17350972.
TY - JOUR
T1 - Adjunctive value of CT coronary angiography in the diagnostic work-up of patients with typical angina pectoris.
AU - Mollet,Nico R,
AU - Cademartiri,Filippo,
AU - Van Mieghem,Carlos,
AU - Meijboom,Bob,
AU - Pugliese,Francesca,
AU - Runza,Giuseppe,
AU - Baks,Timo,
AU - Dikkeboer,Jolmer,
AU - McFadden,Eugene P,
AU - Freericks,Michel P,
AU - Kerker,Jacques P,
AU - Zoet,Stieneke K,
AU - Boersma,Eric,
AU - Krestin,Gabriel P,
AU - de Feyter,Pim J,
Y1 - 2007/03/09/
PY - 2007/3/14/pubmed
PY - 2008/1/9/medline
PY - 2007/3/14/entrez
SP - 1872
EP - 8
JF - European heart journal
JO - Eur Heart J
VL - 28
IS - 15
N2 - AIMS: To determine the adjunctive value of CT coronary angiography (CTCA) in the diagnostic work-up of patients with typical angina pectoris. METHODS AND RESULTS: CTCA was performed in 62 consecutive patients (45 male, mean age 58.8 +/- 7.7 years) with typical angina undergoing diagnostic work-up including exercise-ECG and conventional coronary angiography. Only patients with sinus heart rhythm and ability to breath hold for 20 s were included. Patients with initial heart rates >/=70 beats/min received beta-blockers. We determined the post-test likelihood ratios, to detect or exclude patients with significant (>/=50% lumen diameter reduction) stenoses, of exercise-ECG and CTCA separately, and of CT performed after exercise-ECG testing. The prevalence of patients with significant coronary artery disease (CAD) was 74%. Positive and negative likelihood ratios for exercise-ECG were 2.3 [95% confidence interval (CI): 1.0-5.3] and 0.3 (95% CI: 0.2-0.7) and for CTCA 7.5 (95% CI: 2.1-27.1) and 0.0 (95% CI: 0.0-8), respectively. CTCA increased the post-test probability of significant CAD after a negative exercise-ECG from 58 to 91%, and after a positive exercise-ECG from 89 to 99%, while CT correctly identified patients without CAD (probability 0%). CONCLUSION: Non-invasive CTCA is a potentially useful tool, in the diagnostic work-up of patients with typical angina pectoris, both to detect and to exclude significant CAD.
SN - 0195-668X
UR - https://www.unboundmedicine.com/medline/citation/17350972/Adjunctive_value_of_CT_coronary_angiography_in_the_diagnostic_work_up_of_patients_with_typical_angina_pectoris_
L2 - https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehl563
DB - PRIME
DP - Unbound Medicine
ER -
