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Lead concentrations in maternal blood and breast milk and pediatric blood of Andean villagers: 2006 follow-up investigation.
J Occup Environ Med. 2007 Mar; 49(3):302-9.JO

Abstract

OBJECTIVE

To determine the current lead (Pb) concentration in blood (PbB) and breast milk (PbM) of mothers and the PbB of children living in Andean Ecuadorian villages with high Pb contamination.

METHODS

Samples of whole blood from 93 participants (74 children and 19 adult women) were analyzed for Pb concentration by graphite furnace atomic absorption spectroscopy with Zeeman background correction, and milk samples from nursing mothers were analyzed by inductively coupled plasma-mass spectrometry (ICP-MS).

RESULTS

Mean PbB concentration in children in 2006 was 26.7 microg/dL (SD: 23.0), and significantly lower than the mean PbB level in 1996 to 2000, but similar to the PbB level found in 2003. The mean PbB level of 22.0 microg/dL (SD: 20.6) for the 19 women in the 2006 study group did not differ significantly from the women in the 1996 to 2000 or 2003 study group. The PbM levels (range: 1-49 microg/L) of nursing mothers in the 2006 group were similar to the PbM values observed in the breast milk of nursing mothers in the same study area in 2003, and matched high PbB levels in some mother-infant pairs.

CONCLUSION

This study found elevated, but stable, PbB and PbM levels in mothers and elevated, but stable, PbB levels in children in 2006 that were consistent with the levels observed in 2003 in the same Andean villages.

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Authors+Show Affiliations

Counter SA
Department of Neurology (Dr Counter), Harvard Medical School/The Biological Laboratories, Cambridge, MA 02138, USA. allen_Counter@harvard.edu
Buchanan LH
No affiliation info available
Ortega F
No affiliation info available

MeSH

AdolescentAdultBreast FeedingChildChild, PreschoolEcuadorFemaleFollow-Up StudiesHumansInfantLeadLead PoisoningMaleMass SpectrometryMilk, HumanOccupational ExposureReference ValuesStatistics, Nonparametric

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17351516

Citation

Counter, S Allen, et al. "Lead Concentrations in Maternal Blood and Breast Milk and Pediatric Blood of Andean Villagers: 2006 Follow-up Investigation." Journal of Occupational and Environmental Medicine, vol. 49, no. 3, 2007, pp. 302-9.
Counter SA, Buchanan LH, Ortega F. Lead concentrations in maternal blood and breast milk and pediatric blood of Andean villagers: 2006 follow-up investigation. J Occup Environ Med. 2007;49(3):302-9.
Counter, S. A., Buchanan, L. H., & Ortega, F. (2007). Lead concentrations in maternal blood and breast milk and pediatric blood of Andean villagers: 2006 follow-up investigation. Journal of Occupational and Environmental Medicine, 49(3), 302-9.
Counter SA, Buchanan LH, Ortega F. Lead Concentrations in Maternal Blood and Breast Milk and Pediatric Blood of Andean Villagers: 2006 Follow-up Investigation. J Occup Environ Med. 2007;49(3):302-9. PubMed PMID: 17351516.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lead concentrations in maternal blood and breast milk and pediatric blood of Andean villagers: 2006 follow-up investigation. AU - Counter,S Allen, AU - Buchanan,Leo H, AU - Ortega,Fernando, PY - 2007/3/14/pubmed PY - 2007/5/18/medline PY - 2007/3/14/entrez SP - 302 EP - 9 JF - Journal of occupational and environmental medicine JO - J Occup Environ Med VL - 49 IS - 3 N2 - OBJECTIVE: To determine the current lead (Pb) concentration in blood (PbB) and breast milk (PbM) of mothers and the PbB of children living in Andean Ecuadorian villages with high Pb contamination. METHODS: Samples of whole blood from 93 participants (74 children and 19 adult women) were analyzed for Pb concentration by graphite furnace atomic absorption spectroscopy with Zeeman background correction, and milk samples from nursing mothers were analyzed by inductively coupled plasma-mass spectrometry (ICP-MS). RESULTS: Mean PbB concentration in children in 2006 was 26.7 microg/dL (SD: 23.0), and significantly lower than the mean PbB level in 1996 to 2000, but similar to the PbB level found in 2003. The mean PbB level of 22.0 microg/dL (SD: 20.6) for the 19 women in the 2006 study group did not differ significantly from the women in the 1996 to 2000 or 2003 study group. The PbM levels (range: 1-49 microg/L) of nursing mothers in the 2006 group were similar to the PbM values observed in the breast milk of nursing mothers in the same study area in 2003, and matched high PbB levels in some mother-infant pairs. CONCLUSION: This study found elevated, but stable, PbB and PbM levels in mothers and elevated, but stable, PbB levels in children in 2006 that were consistent with the levels observed in 2003 in the same Andean villages. SN - 1076-2752 UR - https://www.unboundmedicine.com/medline/citation/17351516/Lead_concentrations_in_maternal_blood_and_breast_milk_and_pediatric_blood_of_Andean_villagers:_2006_follow_up_investigation_ L2 - https://doi.org/10.1097/jom.0b013e31803225b0 DB - PRIME DP - Unbound Medicine ER -