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Metabolic syndrome-related conditions among people with and without gout: prevalence and resource use.
Curr Med Res Opin. 2007 Mar; 23(3):623-30.CM

Abstract

OBJECTIVE

A cohort of employees with gout were compared to those without to evaluate the differences in prevalence of disorders associated with metabolic syndrome (both those considered underlying and those associated with end-stage morbidity and mortality) as well as the cost of annual medical services (AMS) required for treatment of these conditions.

METHODS

Employees with gout were identified by International Classification of Diseases-9 (ICD-9) code during the calendar years of 2001-2004 and compared to propensity-score matched employees without gout using the Human Capital Management Services Research Reference Database. T-tests were then used to compare prevalence and average AMS of comorbid disorders defined from Agency for Healthcare and Research Quality (AHRQ) diagnostic categories.

RESULTS

'Hyperlipidemia', 'essential hypertension', and 'diabetes mellitus without complications' ranked in the top 10 categories of mean number of AMS for employees with gout using AHRQ specific categories; the values were higher than found for those without gout (all p < 0.0001). 'Essential hypertension', 'hyperlipidemia', 'diabetes mellitus without complications', and 'coronary atherosclerosis' showed an approximate 2:1 prevalence ratio for employees with gout over those without (p < or = 0.05). Main study limitations include the small number of subjects with gout, retrospective study design, and possible miscoding and/or non-coding of individuals with the studied disorders.

CONCLUSION

These results support the continued need for patients with gout and their clinicians to be aware of the possibility of the increased risk of associated metabolic syndrome and related comorbidities in these individuals, emphasizing the need for prevention when possible and treatment when necessary.

Authors+Show Affiliations

Pharmacy Practice, University of Texas at Austin, Austin, TX, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17355743

Citation

Novak, Suzanne, et al. "Metabolic Syndrome-related Conditions Among People With and Without Gout: Prevalence and Resource Use." Current Medical Research and Opinion, vol. 23, no. 3, 2007, pp. 623-30.
Novak S, Melkonian AK, Patel PA, et al. Metabolic syndrome-related conditions among people with and without gout: prevalence and resource use. Curr Med Res Opin. 2007;23(3):623-30.
Novak, S., Melkonian, A. K., Patel, P. A., Kleinman, N. L., Joseph-Ridge, N., & Brook, R. A. (2007). Metabolic syndrome-related conditions among people with and without gout: prevalence and resource use. Current Medical Research and Opinion, 23(3), 623-30.
Novak S, et al. Metabolic Syndrome-related Conditions Among People With and Without Gout: Prevalence and Resource Use. Curr Med Res Opin. 2007;23(3):623-30. PubMed PMID: 17355743.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Metabolic syndrome-related conditions among people with and without gout: prevalence and resource use. AU - Novak,Suzanne, AU - Melkonian,Arthur K, AU - Patel,Pankaj A, AU - Kleinman,Nathan L, AU - Joseph-Ridge,Nancy, AU - Brook,Richard A, PY - 2007/3/16/pubmed PY - 2007/3/31/medline PY - 2007/3/16/entrez SP - 623 EP - 30 JF - Current medical research and opinion JO - Curr Med Res Opin VL - 23 IS - 3 N2 - OBJECTIVE: A cohort of employees with gout were compared to those without to evaluate the differences in prevalence of disorders associated with metabolic syndrome (both those considered underlying and those associated with end-stage morbidity and mortality) as well as the cost of annual medical services (AMS) required for treatment of these conditions. METHODS: Employees with gout were identified by International Classification of Diseases-9 (ICD-9) code during the calendar years of 2001-2004 and compared to propensity-score matched employees without gout using the Human Capital Management Services Research Reference Database. T-tests were then used to compare prevalence and average AMS of comorbid disorders defined from Agency for Healthcare and Research Quality (AHRQ) diagnostic categories. RESULTS: 'Hyperlipidemia', 'essential hypertension', and 'diabetes mellitus without complications' ranked in the top 10 categories of mean number of AMS for employees with gout using AHRQ specific categories; the values were higher than found for those without gout (all p < 0.0001). 'Essential hypertension', 'hyperlipidemia', 'diabetes mellitus without complications', and 'coronary atherosclerosis' showed an approximate 2:1 prevalence ratio for employees with gout over those without (p < or = 0.05). Main study limitations include the small number of subjects with gout, retrospective study design, and possible miscoding and/or non-coding of individuals with the studied disorders. CONCLUSION: These results support the continued need for patients with gout and their clinicians to be aware of the possibility of the increased risk of associated metabolic syndrome and related comorbidities in these individuals, emphasizing the need for prevention when possible and treatment when necessary. SN - 1473-4877 UR - https://www.unboundmedicine.com/medline/citation/17355743/Metabolic_syndrome_related_conditions_among_people_with_and_without_gout:_prevalence_and_resource_use_ L2 - https://www.tandfonline.com/doi/full/10.1185/030079906X167651 DB - PRIME DP - Unbound Medicine ER -