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Effect of dietary alpha-linolenic fatty acid derived from chia when fed as ground seed, whole seed and oil on lipid content and fatty acid composition of rat plasma.
Ann Nutr Metab. 2007; 51(1):27-34.AN

Abstract

Coronary heart disease (CHD) is the most common cause of death in the Western world. In both the USA and the EU it accounts for over 600,000 deaths yearly. Early data showing the benefits n-3 fatty acids provide in preventing CHD disease were obtained using 20:5n-3 and 22:6n-3 fatty acids derived from fish. Recently, however, it has been shown that reduced risks of CHD and other cardiovascular diseases are found with 18:3n-3 fatty acid as well. To determine if 18:3n-3 fatty acids positively influence plasma composition, 32 male Wistar rats were fed ad libitum four isocaloric diets with the energy derived from corn oil (T(1)), whole chia seed (T(2)), ground chia seed (T(3)), or chia oil (T(4)) for 30 days. At the end of the feeding period the rats were sacrificed, and blood samples were analyzed to determine serum CHOL, HDL, LDL, TG content, hemogram, and fatty acid composition. Chia decreased serum TG content and increased HDL content. Only with the T(2) diet was TG significantly (p < 0.05) lower, and only with the T(3) diet was HDL significantly (p < 0.05) higher, than the control diet. Chia significantly (p < 0.05) increased the 18:3n-3, 20:5n-3 and 22:6n-3 plasma contents compared to the control diet, with no significant (p < 0.05) difference among chia diets detected. Significant (p < 0.05) improvement in n-6/n-3 fatty acid ratio was observed for all chia diets when compared to the control.

Authors+Show Affiliations

Office of Arid Lands Studies, The University of Arizona, Tucson, AZ 85637, USA.No affiliation info available

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17356263

Citation

Ayerza, Ricardo, and Wayne Coates. "Effect of Dietary Alpha-linolenic Fatty Acid Derived From Chia when Fed as Ground Seed, Whole Seed and Oil On Lipid Content and Fatty Acid Composition of Rat Plasma." Annals of Nutrition & Metabolism, vol. 51, no. 1, 2007, pp. 27-34.
Ayerza R, Coates W. Effect of dietary alpha-linolenic fatty acid derived from chia when fed as ground seed, whole seed and oil on lipid content and fatty acid composition of rat plasma. Ann Nutr Metab. 2007;51(1):27-34.
Ayerza, R., & Coates, W. (2007). Effect of dietary alpha-linolenic fatty acid derived from chia when fed as ground seed, whole seed and oil on lipid content and fatty acid composition of rat plasma. Annals of Nutrition & Metabolism, 51(1), 27-34.
Ayerza R, Coates W. Effect of Dietary Alpha-linolenic Fatty Acid Derived From Chia when Fed as Ground Seed, Whole Seed and Oil On Lipid Content and Fatty Acid Composition of Rat Plasma. Ann Nutr Metab. 2007;51(1):27-34. PubMed PMID: 17356263.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of dietary alpha-linolenic fatty acid derived from chia when fed as ground seed, whole seed and oil on lipid content and fatty acid composition of rat plasma. AU - Ayerza,Ricardo,Jr AU - Coates,Wayne, Y1 - 2007/03/14/ PY - 2006/02/13/received PY - 2006/08/18/accepted PY - 2007/3/16/pubmed PY - 2007/5/4/medline PY - 2007/3/16/entrez SP - 27 EP - 34 JF - Annals of nutrition & metabolism JO - Ann Nutr Metab VL - 51 IS - 1 N2 - Coronary heart disease (CHD) is the most common cause of death in the Western world. In both the USA and the EU it accounts for over 600,000 deaths yearly. Early data showing the benefits n-3 fatty acids provide in preventing CHD disease were obtained using 20:5n-3 and 22:6n-3 fatty acids derived from fish. Recently, however, it has been shown that reduced risks of CHD and other cardiovascular diseases are found with 18:3n-3 fatty acid as well. To determine if 18:3n-3 fatty acids positively influence plasma composition, 32 male Wistar rats were fed ad libitum four isocaloric diets with the energy derived from corn oil (T(1)), whole chia seed (T(2)), ground chia seed (T(3)), or chia oil (T(4)) for 30 days. At the end of the feeding period the rats were sacrificed, and blood samples were analyzed to determine serum CHOL, HDL, LDL, TG content, hemogram, and fatty acid composition. Chia decreased serum TG content and increased HDL content. Only with the T(2) diet was TG significantly (p < 0.05) lower, and only with the T(3) diet was HDL significantly (p < 0.05) higher, than the control diet. Chia significantly (p < 0.05) increased the 18:3n-3, 20:5n-3 and 22:6n-3 plasma contents compared to the control diet, with no significant (p < 0.05) difference among chia diets detected. Significant (p < 0.05) improvement in n-6/n-3 fatty acid ratio was observed for all chia diets when compared to the control. SN - 1421-9697 UR - https://www.unboundmedicine.com/medline/citation/17356263/Effect_of_dietary_alpha_linolenic_fatty_acid_derived_from_chia_when_fed_as_ground_seed_whole_seed_and_oil_on_lipid_content_and_fatty_acid_composition_of_rat_plasma_ L2 - https://www.karger.com?DOI=10.1159/000100818 DB - PRIME DP - Unbound Medicine ER -