Tags

Type your tag names separated by a space and hit enter

Children and young adults in a prolonged unconscious state after severe brain injury: long-term functional outcome as measured by the DRS and the GOSE after early intensive neurorehabilitation.
Brain Inj. 2007 Jan; 21(1):53-61.BI

Abstract

OBJECTIVE

To investigate the long-term (2-15 years) functional outcome of children and young adults who received an early intensive neurorehabilitation programme (EINP) after a prolonged period of unconsciousness due to severe brain injury; to differentiate between traumatic brain injury (TBI) and non-traumatic brain injury (nTBI); and to compare the results on two different outcome scales: the Disability Rating Scale (DRS) and the Glasgow Outcome Scale Extended (GOSE).

SUBJECTS

One hundred and forty-five patients, who were admitted to EINP between December 1987 and January 2001.

OUTCOME MEASURES

The Post-Acute Level of Consciousness scale (PALOC-s), the DRS, including categorized scores (DRScat), and the GOSE.

RESULTS

The long-term functional level of 90 patients could be determined, of whom 25 were deceased. The mean DRS-score of the surviving patients was 6.8 (SD = 6.6); the mean score on the GOSE was 4.5 (SD = 1.7). There was a significant difference in the outcome amongst traumatic and non-traumatic patients (t88 = 4.21; p < 0.01). The correlation between the DRS and the GOSE was high (Spearman rho = 0.85; p < 0.01), as well as the correlation between the categorized scores of the DRS and the GOSE (Spearman rho = 0.81; p < 0.01). The distribution of outcome scores on the DRScat is more diverse than on the GOSE. Especially item 7 of the DRS, measuring functional independence, showed considerable variance in discriminating between different outcome levels.

CONCLUSIONS

More patients with TBI than expected reached a (semi-) independent level of functioning, indicating a possible effect of EINP. Patients suffering from nTBI did not demonstrate these outcome levels. Only a few patients stayed in a vegetative state for more than a couple of years. In this cohort of severe brain-injured young people, the DRS offered the best investigative possibilities for long-term level of functioning.

Authors+Show Affiliations

Rehabilitation Centre Leijpark. Division Research, Project VLB-NAH, Tilburg. H.J.Eilander@hccnet.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17364520

Citation

Eilander, H J., et al. "Children and Young Adults in a Prolonged Unconscious State After Severe Brain Injury: Long-term Functional Outcome as Measured By the DRS and the GOSE After Early Intensive Neurorehabilitation." Brain Injury, vol. 21, no. 1, 2007, pp. 53-61.
Eilander HJ, Timmerman RB, Scheirs JG, et al. Children and young adults in a prolonged unconscious state after severe brain injury: long-term functional outcome as measured by the DRS and the GOSE after early intensive neurorehabilitation. Brain Inj. 2007;21(1):53-61.
Eilander, H. J., Timmerman, R. B., Scheirs, J. G., Van Heugten, C. M., De Kort, P. L., & Prevo, A. J. (2007). Children and young adults in a prolonged unconscious state after severe brain injury: long-term functional outcome as measured by the DRS and the GOSE after early intensive neurorehabilitation. Brain Injury, 21(1), 53-61.
Eilander HJ, et al. Children and Young Adults in a Prolonged Unconscious State After Severe Brain Injury: Long-term Functional Outcome as Measured By the DRS and the GOSE After Early Intensive Neurorehabilitation. Brain Inj. 2007;21(1):53-61. PubMed PMID: 17364520.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Children and young adults in a prolonged unconscious state after severe brain injury: long-term functional outcome as measured by the DRS and the GOSE after early intensive neurorehabilitation. AU - Eilander,H J, AU - Timmerman,R B W, AU - Scheirs,J G M, AU - Van Heugten,C M, AU - De Kort,P L M, AU - Prevo,A J H, PY - 2007/3/17/pubmed PY - 2007/12/6/medline PY - 2007/3/17/entrez SP - 53 EP - 61 JF - Brain injury JO - Brain Inj VL - 21 IS - 1 N2 - OBJECTIVE: To investigate the long-term (2-15 years) functional outcome of children and young adults who received an early intensive neurorehabilitation programme (EINP) after a prolonged period of unconsciousness due to severe brain injury; to differentiate between traumatic brain injury (TBI) and non-traumatic brain injury (nTBI); and to compare the results on two different outcome scales: the Disability Rating Scale (DRS) and the Glasgow Outcome Scale Extended (GOSE). SUBJECTS: One hundred and forty-five patients, who were admitted to EINP between December 1987 and January 2001. OUTCOME MEASURES: The Post-Acute Level of Consciousness scale (PALOC-s), the DRS, including categorized scores (DRScat), and the GOSE. RESULTS: The long-term functional level of 90 patients could be determined, of whom 25 were deceased. The mean DRS-score of the surviving patients was 6.8 (SD = 6.6); the mean score on the GOSE was 4.5 (SD = 1.7). There was a significant difference in the outcome amongst traumatic and non-traumatic patients (t88 = 4.21; p < 0.01). The correlation between the DRS and the GOSE was high (Spearman rho = 0.85; p < 0.01), as well as the correlation between the categorized scores of the DRS and the GOSE (Spearman rho = 0.81; p < 0.01). The distribution of outcome scores on the DRScat is more diverse than on the GOSE. Especially item 7 of the DRS, measuring functional independence, showed considerable variance in discriminating between different outcome levels. CONCLUSIONS: More patients with TBI than expected reached a (semi-) independent level of functioning, indicating a possible effect of EINP. Patients suffering from nTBI did not demonstrate these outcome levels. Only a few patients stayed in a vegetative state for more than a couple of years. In this cohort of severe brain-injured young people, the DRS offered the best investigative possibilities for long-term level of functioning. SN - 0269-9052 UR - https://www.unboundmedicine.com/medline/citation/17364520/Children_and_young_adults_in_a_prolonged_unconscious_state_after_severe_brain_injury:_long_term_functional_outcome_as_measured_by_the_DRS_and_the_GOSE_after_early_intensive_neurorehabilitation_ L2 - http://www.tandfonline.com/doi/full/10.1080/02699050601151795 DB - PRIME DP - Unbound Medicine ER -