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Performance of glucose dehydrogenase (GDH) based and glucose oxidase (GOX) based blood glucose meter systems at moderately high altitude.
J Med Eng Technol. 2007 Mar-Apr; 31(2):152-6.JM

Abstract

OBJECTIVE

Self-monitoring of blood glucose (SMBG) is a fairly efficient method of preventing hypoglycaemia in diabetic patients. Blood glucose meters (BGMs) are influenced by factors such as altitude, temperature, blood oxygen concentration, low atmospheric pressure or humidity. In this study we aimed at evaluating the performance of glucose dehydrogenase (GDH) or glucose oxidase (GOX) based glucometers at moderately high altitude.

METHOD

A total of 286 female or male patients, most of whom had type 2 diabetes, were included in this study. The simultaneous readings made by two different glucometers were compared with the readings made at the reference laboratory.

RESULTS

Blood glucose levels measured by a GDH based glucometer at moderately high altitude were significantly (p=0.007) higher compared to those measured at the reference laboratory. Although blood glucose levels measured by a GOX based glucometer were lower compared to those measured at the reference laboratory, the difference was not significant (p=0.54). The difference between GOX and GDH readings with regard to blood glucose levels was also significant (p=0.001). Blood glucometers were influenced by moderately high altitude.

CONCLUSION

The use of a GOX based glucometer at moderately high altitude may be useful in detecting hypoglycaemia at these conditions, since significantly higher blood glucose levels were measured with a GDH based glucometer compared to reference readings.

Authors+Show Affiliations

Division of Endocrinology, School of Medicine, University of Atatürk, Erzurum, Turkey. drbilen@atauni.edu.trNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Validation Study

Language

eng

PubMed ID

17365439

Citation

Bilen, H, et al. "Performance of Glucose Dehydrogenase (GDH) Based and Glucose Oxidase (GOX) Based Blood Glucose Meter Systems at Moderately High Altitude." Journal of Medical Engineering & Technology, vol. 31, no. 2, 2007, pp. 152-6.
Bilen H, Kilicaslan A, Akcay G, et al. Performance of glucose dehydrogenase (GDH) based and glucose oxidase (GOX) based blood glucose meter systems at moderately high altitude. J Med Eng Technol. 2007;31(2):152-6.
Bilen, H., Kilicaslan, A., Akcay, G., & Albayrak, F. (2007). Performance of glucose dehydrogenase (GDH) based and glucose oxidase (GOX) based blood glucose meter systems at moderately high altitude. Journal of Medical Engineering & Technology, 31(2), 152-6.
Bilen H, et al. Performance of Glucose Dehydrogenase (GDH) Based and Glucose Oxidase (GOX) Based Blood Glucose Meter Systems at Moderately High Altitude. J Med Eng Technol. 2007 Mar-Apr;31(2):152-6. PubMed PMID: 17365439.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Performance of glucose dehydrogenase (GDH) based and glucose oxidase (GOX) based blood glucose meter systems at moderately high altitude. AU - Bilen,H, AU - Kilicaslan,A, AU - Akcay,G, AU - Albayrak,F, PY - 2007/3/17/pubmed PY - 2007/5/17/medline PY - 2007/3/17/entrez SP - 152 EP - 6 JF - Journal of medical engineering & technology JO - J Med Eng Technol VL - 31 IS - 2 N2 - OBJECTIVE: Self-monitoring of blood glucose (SMBG) is a fairly efficient method of preventing hypoglycaemia in diabetic patients. Blood glucose meters (BGMs) are influenced by factors such as altitude, temperature, blood oxygen concentration, low atmospheric pressure or humidity. In this study we aimed at evaluating the performance of glucose dehydrogenase (GDH) or glucose oxidase (GOX) based glucometers at moderately high altitude. METHOD: A total of 286 female or male patients, most of whom had type 2 diabetes, were included in this study. The simultaneous readings made by two different glucometers were compared with the readings made at the reference laboratory. RESULTS: Blood glucose levels measured by a GDH based glucometer at moderately high altitude were significantly (p=0.007) higher compared to those measured at the reference laboratory. Although blood glucose levels measured by a GOX based glucometer were lower compared to those measured at the reference laboratory, the difference was not significant (p=0.54). The difference between GOX and GDH readings with regard to blood glucose levels was also significant (p=0.001). Blood glucometers were influenced by moderately high altitude. CONCLUSION: The use of a GOX based glucometer at moderately high altitude may be useful in detecting hypoglycaemia at these conditions, since significantly higher blood glucose levels were measured with a GDH based glucometer compared to reference readings. SN - 0309-1902 UR - https://www.unboundmedicine.com/medline/citation/17365439/Performance_of_glucose_dehydrogenase__GDH__based_and_glucose_oxidase__GOX__based_blood_glucose_meter_systems_at_moderately_high_altitude_ L2 - https://www.tandfonline.com/doi/full/10.1080/03091900600861590 DB - PRIME DP - Unbound Medicine ER -