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A case report of Wernicke's encephalopathy in a pediatric patient with anorexia nervosa--restricting type.
J Adolesc Health. 2007 Apr; 40(4):376-83.JA

Abstract

PURPOSE

To describe a case of Wernicke's encephalopathy in a 15-year-old female patient with anorexia nervosa--restricting type.

METHOD

The patient and family were interviewed. Literature relevant to the case was reviewed prior to diagnosis.

RESULTS

The patient reported a 30-kg weight loss over a 6-month period, following a strict diet deplete in thiamine without vitamin supplementation. The patient reported a carbohydrate binge for 5 days prior to admission. Her clinical presentation, confusion, ataxia, nystagmus, and magnetic resonance imaging demonstrating bilateral subthalamic hyperdensities were consistent with Wernicke's encephalopathy. Nutritional stabilization and parenteral thiamine replacement resulted in rapid improvement of her ataxia and nystagmus and contributed to her recovery.

CONCLUSIONS

Wernicke's encephalopathy should be considered in patients with anorexia nervosa. Thiamine therapy could be considered in cases of anorexia nervosa with significant confusion.

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Authors+Show Affiliations

Peters TE
Brown Medical School, Providence, Rhode Island, USA. Todd_Peters@brown.edu <Todd_Peters@brown.edu>
Parvin M
No affiliation info available
Petersen C
No affiliation info available
Faircloth VC
No affiliation info available
Levine RL
No affiliation info available

MeSH

AdolescentAnorexia NervosaFemaleHumansMalnutritionThiamineThiamine DeficiencyWernicke Encephalopathy

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17367738

Citation

Peters, Todd E., et al. "A Case Report of Wernicke's Encephalopathy in a Pediatric Patient With Anorexia Nervosa--restricting Type." The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, vol. 40, no. 4, 2007, pp. 376-83.
Peters TE, Parvin M, Petersen C, et al. A case report of Wernicke's encephalopathy in a pediatric patient with anorexia nervosa--restricting type. J Adolesc Health. 2007;40(4):376-83.
Peters, T. E., Parvin, M., Petersen, C., Faircloth, V. C., & Levine, R. L. (2007). A case report of Wernicke's encephalopathy in a pediatric patient with anorexia nervosa--restricting type. The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, 40(4), 376-83.
Peters TE, et al. A Case Report of Wernicke's Encephalopathy in a Pediatric Patient With Anorexia Nervosa--restricting Type. J Adolesc Health. 2007;40(4):376-83. PubMed PMID: 17367738.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A case report of Wernicke's encephalopathy in a pediatric patient with anorexia nervosa--restricting type. AU - Peters,Todd E, AU - Parvin,Matthew, AU - Petersen,Christopher, AU - Faircloth,Vivian C, AU - Levine,Richard L, Y1 - 2007/02/05/ PY - 2006/08/23/received PY - 2006/11/03/revised PY - 2006/11/14/accepted PY - 2007/3/21/pubmed PY - 2007/3/29/medline PY - 2007/3/21/entrez SP - 376 EP - 83 JF - The Journal of adolescent health : official publication of the Society for Adolescent Medicine JO - J Adolesc Health VL - 40 IS - 4 N2 - PURPOSE: To describe a case of Wernicke's encephalopathy in a 15-year-old female patient with anorexia nervosa--restricting type. METHOD: The patient and family were interviewed. Literature relevant to the case was reviewed prior to diagnosis. RESULTS: The patient reported a 30-kg weight loss over a 6-month period, following a strict diet deplete in thiamine without vitamin supplementation. The patient reported a carbohydrate binge for 5 days prior to admission. Her clinical presentation, confusion, ataxia, nystagmus, and magnetic resonance imaging demonstrating bilateral subthalamic hyperdensities were consistent with Wernicke's encephalopathy. Nutritional stabilization and parenteral thiamine replacement resulted in rapid improvement of her ataxia and nystagmus and contributed to her recovery. CONCLUSIONS: Wernicke's encephalopathy should be considered in patients with anorexia nervosa. Thiamine therapy could be considered in cases of anorexia nervosa with significant confusion. SN - 1879-1972 UR - https://www.unboundmedicine.com/medline/citation/17367738/A_case_report_of_Wernicke's_encephalopathy_in_a_pediatric_patient_with_anorexia_nervosa__restricting_type_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1054-139X(06)00567-2 DB - PRIME DP - Unbound Medicine ER -