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Biochemical, physiological, and histological changes in the neotropical fish Prochilodus lineatus exposed to diesel oil.
Ecotoxicol Environ Saf. 2008 Jan; 69(1):112-20.EE

Abstract

Toxicity tests were conducted simulating a diesel oil spill in a tropical environment and juveniles of Prochilodus lineatus were exposed to the water-soluble fraction of diesel oil (WSD) for 6, 24, 96 h, and 15 days. The results showed the activation of biotransformation pathways for xenobiotics, through a time-dependent increase of liver GST activity. WSD caused a decrease in hematocrit and hemoglobin content, very likely due to hemolysis. Furthermore, an increase in glucose levels was observed after acute exposure to WSD. A possible lack of cortisol response could also be associated with WSD, since a reduction in plasma cortisol was seen in fish exposed to the petroleum product for 15 days. Moreover, the occurrence of lesions in the gills and even more severe lesions in the liver, should lead to functional damage to both organs, interfering thus directly with fundamental processes for the maintenance of homeostasis in this fish.

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Authors+Show Affiliations

Simonato JD
Departamento de Ciências Fisiológicas, Universidade Estadual de Londrina, C.P. 6001, CEP:86051-990, Londrina, Paraná, Brasil.
Guedes CL
No affiliation info available
Martinez CB
No affiliation info available

MeSH

AnimalsBlood GlucoseCatalaseFishesGasolineGillsGlutathione TransferaseHydrocortisoneLiverToxicity TestsWater Pollutants, Chemical

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17368761

Citation

Simonato, Juliana Delatim, et al. "Biochemical, Physiological, and Histological Changes in the Neotropical Fish Prochilodus Lineatus Exposed to Diesel Oil." Ecotoxicology and Environmental Safety, vol. 69, no. 1, 2008, pp. 112-20.
Simonato JD, Guedes CL, Martinez CB. Biochemical, physiological, and histological changes in the neotropical fish Prochilodus lineatus exposed to diesel oil. Ecotoxicol Environ Saf. 2008;69(1):112-20.
Simonato, J. D., Guedes, C. L., & Martinez, C. B. (2008). Biochemical, physiological, and histological changes in the neotropical fish Prochilodus lineatus exposed to diesel oil. Ecotoxicology and Environmental Safety, 69(1), 112-20.
Simonato JD, Guedes CL, Martinez CB. Biochemical, Physiological, and Histological Changes in the Neotropical Fish Prochilodus Lineatus Exposed to Diesel Oil. Ecotoxicol Environ Saf. 2008;69(1):112-20. PubMed PMID: 17368761.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biochemical, physiological, and histological changes in the neotropical fish Prochilodus lineatus exposed to diesel oil. AU - Simonato,Juliana Delatim, AU - Guedes,Carmen L B, AU - Martinez,Cláudia B R, Y1 - 2007/03/21/ PY - 2006/07/18/received PY - 2007/01/24/revised PY - 2007/3/21/pubmed PY - 2008/2/15/medline PY - 2007/3/21/entrez SP - 112 EP - 20 JF - Ecotoxicology and environmental safety JO - Ecotoxicol Environ Saf VL - 69 IS - 1 N2 - Toxicity tests were conducted simulating a diesel oil spill in a tropical environment and juveniles of Prochilodus lineatus were exposed to the water-soluble fraction of diesel oil (WSD) for 6, 24, 96 h, and 15 days. The results showed the activation of biotransformation pathways for xenobiotics, through a time-dependent increase of liver GST activity. WSD caused a decrease in hematocrit and hemoglobin content, very likely due to hemolysis. Furthermore, an increase in glucose levels was observed after acute exposure to WSD. A possible lack of cortisol response could also be associated with WSD, since a reduction in plasma cortisol was seen in fish exposed to the petroleum product for 15 days. Moreover, the occurrence of lesions in the gills and even more severe lesions in the liver, should lead to functional damage to both organs, interfering thus directly with fundamental processes for the maintenance of homeostasis in this fish. SN - 0147-6513 UR - https://www.unboundmedicine.com/medline/citation/17368761/Biochemical_physiological_and_histological_changes_in_the_neotropical_fish_Prochilodus_lineatus_exposed_to_diesel_oil_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0147-6513(07)00035-8 DB - PRIME DP - Unbound Medicine ER -