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An in vitro assessment of the antibacterial effect of garlic (Allium sativum) on bacterial isolates from wound infections.
Ethiop Med J. 2006 Oct; 44(4):385-9.EM

Abstract

BACKGROUND

Garlic (Allium sativum) has come to be seen as an all rounded treatment for preventing wound infection, common cold, malaria, cough and lung tuberculosis, hypertension, sexually transmitted diseases, mental illness, kidney diseases, liver diseases, asthma, diabetes.

OBJECTIVE

The main objective of this study was to assess the antibacterial effect of crude preparation of garlic on bacterial isolates from the wound infections.

METHODS

An experimental study was conducted in Gondar University Teaching Hospital School of Medical Laboratory Technology, Microbiology Laboratory from June 2004 to April 2005 by agar dilution technique. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of garlic to control strains of Staphylococcus aureus ATTC 25923 and Escherichia coli ATTCC 25922, as well as to clinical isolates of S. aureus, E. coli, Proteus mirabilis, Klebsiella pneumoniae and Pseudomonas aeruginosa were determined using agar dilution method The data was collected in triplicate.

RESULTS

All the tested organisms were inhibited by 33.75 mg/ml of the crude preparation of garlic except control organism and clinical isolates of S. aureus, which were inhibited by 11.25 mg/ml of crude garlic. Garlic did not reveal bactericidal effect up to a concentration of 37.5 mg/ml against all the tested organisms.

CONCLUSION

Crude preparation of garlic could be used as an effective antibacterial agent for the tested organisms. Nevertheless, clinical trial on the effect of garlic is essential before advocating large-scale therapy.

Authors+Show Affiliations

University of Gondar, College of Medicine and Health Sciences, School of Medical Laboratory Technology, P.O. Box 196, Gondar, Ethiopia. Bt1488@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17370439

Citation

Tessema, Belay, et al. "An in Vitro Assessment of the Antibacterial Effect of Garlic (Allium Sativum) On Bacterial Isolates From Wound Infections." Ethiopian Medical Journal, vol. 44, no. 4, 2006, pp. 385-9.
Tessema B, Mulu A, Kassu A, et al. An in vitro assessment of the antibacterial effect of garlic (Allium sativum) on bacterial isolates from wound infections. Ethiop Med J. 2006;44(4):385-9.
Tessema, B., Mulu, A., Kassu, A., & Yismaw, G. (2006). An in vitro assessment of the antibacterial effect of garlic (Allium sativum) on bacterial isolates from wound infections. Ethiopian Medical Journal, 44(4), 385-9.
Tessema B, et al. An in Vitro Assessment of the Antibacterial Effect of Garlic (Allium Sativum) On Bacterial Isolates From Wound Infections. Ethiop Med J. 2006;44(4):385-9. PubMed PMID: 17370439.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An in vitro assessment of the antibacterial effect of garlic (Allium sativum) on bacterial isolates from wound infections. AU - Tessema,Belay, AU - Mulu,Andargachew, AU - Kassu,Afework, AU - Yismaw,Gizachew, PY - 2007/3/21/pubmed PY - 2007/12/18/medline PY - 2007/3/21/entrez SP - 385 EP - 9 JF - Ethiopian medical journal JO - Ethiop Med J VL - 44 IS - 4 N2 - BACKGROUND: Garlic (Allium sativum) has come to be seen as an all rounded treatment for preventing wound infection, common cold, malaria, cough and lung tuberculosis, hypertension, sexually transmitted diseases, mental illness, kidney diseases, liver diseases, asthma, diabetes. OBJECTIVE: The main objective of this study was to assess the antibacterial effect of crude preparation of garlic on bacterial isolates from the wound infections. METHODS: An experimental study was conducted in Gondar University Teaching Hospital School of Medical Laboratory Technology, Microbiology Laboratory from June 2004 to April 2005 by agar dilution technique. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of garlic to control strains of Staphylococcus aureus ATTC 25923 and Escherichia coli ATTCC 25922, as well as to clinical isolates of S. aureus, E. coli, Proteus mirabilis, Klebsiella pneumoniae and Pseudomonas aeruginosa were determined using agar dilution method The data was collected in triplicate. RESULTS: All the tested organisms were inhibited by 33.75 mg/ml of the crude preparation of garlic except control organism and clinical isolates of S. aureus, which were inhibited by 11.25 mg/ml of crude garlic. Garlic did not reveal bactericidal effect up to a concentration of 37.5 mg/ml against all the tested organisms. CONCLUSION: Crude preparation of garlic could be used as an effective antibacterial agent for the tested organisms. Nevertheless, clinical trial on the effect of garlic is essential before advocating large-scale therapy. SN - 0014-1755 UR - https://www.unboundmedicine.com/medline/citation/17370439/An_in_vitro_assessment_of_the_antibacterial_effect_of_garlic__Allium_sativum__on_bacterial_isolates_from_wound_infections_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -