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Obesity and the risk of gallbladder cancer: a meta-analysis.
Br J Cancer 2007; 96(9):1457-61BJ

Abstract

We performed a meta-analysis of studies of the association between excess body weight and risk of gallbladder cancer identified from MEDLINE and EMBASE databases from 1966 to February 2007 and the references of retrieved articles. A random-effects model was used to combine results from eight cohort studies and three case-control studies, with a total of 3288 cases. Compared with individuals of 'normal weight', the summary relative risk of gallbladder cancer for those who were overweight or obese was 1.15 (95% CI, 1.01-1.30) and 1.66 (95% CI, 1.47-1.88) respectively. The association with obesity was stronger for women (relative risk, 1.88; 95% CI, 1.66-2.13) than for men (relative risk, 1.35; 95% CI, 1.09-1.68). There was no statistically significant heterogeneity among the results of individual studies. This meta-analysis confirms the association between excess body weight and risk of gallbladder cancer.

Authors+Show Affiliations

Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-17177 Stockholm, Sweden. susanna.larsson@ki.se

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17375043

Citation

Larsson, S C., and A Wolk. "Obesity and the Risk of Gallbladder Cancer: a Meta-analysis." British Journal of Cancer, vol. 96, no. 9, 2007, pp. 1457-61.
Larsson SC, Wolk A. Obesity and the risk of gallbladder cancer: a meta-analysis. Br J Cancer. 2007;96(9):1457-61.
Larsson, S. C., & Wolk, A. (2007). Obesity and the risk of gallbladder cancer: a meta-analysis. British Journal of Cancer, 96(9), pp. 1457-61.
Larsson SC, Wolk A. Obesity and the Risk of Gallbladder Cancer: a Meta-analysis. Br J Cancer. 2007 May 7;96(9):1457-61. PubMed PMID: 17375043.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obesity and the risk of gallbladder cancer: a meta-analysis. AU - Larsson,S C, AU - Wolk,A, Y1 - 2007/03/20/ PY - 2007/3/22/pubmed PY - 2007/9/13/medline PY - 2007/3/22/entrez SP - 1457 EP - 61 JF - British journal of cancer JO - Br. J. Cancer VL - 96 IS - 9 N2 - We performed a meta-analysis of studies of the association between excess body weight and risk of gallbladder cancer identified from MEDLINE and EMBASE databases from 1966 to February 2007 and the references of retrieved articles. A random-effects model was used to combine results from eight cohort studies and three case-control studies, with a total of 3288 cases. Compared with individuals of 'normal weight', the summary relative risk of gallbladder cancer for those who were overweight or obese was 1.15 (95% CI, 1.01-1.30) and 1.66 (95% CI, 1.47-1.88) respectively. The association with obesity was stronger for women (relative risk, 1.88; 95% CI, 1.66-2.13) than for men (relative risk, 1.35; 95% CI, 1.09-1.68). There was no statistically significant heterogeneity among the results of individual studies. This meta-analysis confirms the association between excess body weight and risk of gallbladder cancer. SN - 0007-0920 UR - https://www.unboundmedicine.com/medline/citation/17375043/Obesity_and_the_risk_of_gallbladder_cancer:_a_meta_analysis_ L2 - http://dx.doi.org/10.1038/sj.bjc.6603703 DB - PRIME DP - Unbound Medicine ER -