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Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer.
Public Health Nutr 2007; 10(8):769-79PH

Abstract

OBJECTIVE

Valid dietary data are essential when trying to identify whether or not one or more dietary exposures are responsible for disease. We examined diet composition in women who reported dietary change in the past compared with non-changers, and how the associations between dietary factors and postmenopausal breast cancer are influenced by dietary change, obesity status and misreporting of energy.

DESIGN

A population-based prospective cohort study. Data were obtained by a diet history method, anthropometrical measurements and an extensive lifestyle questionnaire including items on past food habit change.

SETTING

The Malmö Diet and Cancer (MDC) study, conducted in Malmö, Sweden.

SUBJECTS

A subsample of 12,781 women from the MDC cohort recruited from 1991 to 1996. A total of 428 postmenopausal women were diagnosed with incident breast cancer, during 9.2 years of follow-up.

RESULTS

Past food habit changers reported healthier food habits and lower energy intake compared with non-changers, a finding that raises issues regarding possible reporting biases. When excluding diet changers, the trend of increased breast cancer risk across omega-6 fatty acid quintiles was stronger, and a tendency of decreased risk emerged for 'fruit, berries and vegetables'. When excluding individuals with non-adequate reports of energy intake, risk estimates were similar to that of the whole sample. In women with body mass index < 27 kg m- 2, significant trends of increased breast cancer risk were seen for total fat and omega-6 fatty acids, and of decreased risk for 'fruit, berries and vegetables'.

CONCLUSIONS

This study indicates that both obesity and self-reported past food habit change may be important confounders of diet-breast cancer relationships. The study demonstrates that sensitivity analysis, through stratification, may facilitate interpretation of risk relationships and study results.

Authors+Show Affiliations

Lund University, Department of Clinical Sciences Malmö, Building 60 floor 13, CRC entrance 72 UMAS, SE-20502 Malmö, Sweden. Sonestedt@med.lu.seNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17381916

Citation

Sonestedt, Emily, et al. "Both Food Habit Change in the Past and Obesity Status May Influence the Association Between Dietary Factors and Postmenopausal Breast Cancer." Public Health Nutrition, vol. 10, no. 8, 2007, pp. 769-79.
Sonestedt E, Gullberg B, Wirfält E. Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer. Public Health Nutr. 2007;10(8):769-79.
Sonestedt, E., Gullberg, B., & Wirfält, E. (2007). Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer. Public Health Nutrition, 10(8), pp. 769-79.
Sonestedt E, Gullberg B, Wirfält E. Both Food Habit Change in the Past and Obesity Status May Influence the Association Between Dietary Factors and Postmenopausal Breast Cancer. Public Health Nutr. 2007;10(8):769-79. PubMed PMID: 17381916.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer. AU - Sonestedt,Emily, AU - Gullberg,Bo, AU - Wirfält,Elisabet, Y1 - 2007/03/05/ PY - 2007/3/27/pubmed PY - 2007/10/10/medline PY - 2007/3/27/entrez SP - 769 EP - 79 JF - Public health nutrition JO - Public Health Nutr VL - 10 IS - 8 N2 - OBJECTIVE: Valid dietary data are essential when trying to identify whether or not one or more dietary exposures are responsible for disease. We examined diet composition in women who reported dietary change in the past compared with non-changers, and how the associations between dietary factors and postmenopausal breast cancer are influenced by dietary change, obesity status and misreporting of energy. DESIGN: A population-based prospective cohort study. Data were obtained by a diet history method, anthropometrical measurements and an extensive lifestyle questionnaire including items on past food habit change. SETTING: The Malmö Diet and Cancer (MDC) study, conducted in Malmö, Sweden. SUBJECTS: A subsample of 12,781 women from the MDC cohort recruited from 1991 to 1996. A total of 428 postmenopausal women were diagnosed with incident breast cancer, during 9.2 years of follow-up. RESULTS: Past food habit changers reported healthier food habits and lower energy intake compared with non-changers, a finding that raises issues regarding possible reporting biases. When excluding diet changers, the trend of increased breast cancer risk across omega-6 fatty acid quintiles was stronger, and a tendency of decreased risk emerged for 'fruit, berries and vegetables'. When excluding individuals with non-adequate reports of energy intake, risk estimates were similar to that of the whole sample. In women with body mass index < 27 kg m- 2, significant trends of increased breast cancer risk were seen for total fat and omega-6 fatty acids, and of decreased risk for 'fruit, berries and vegetables'. CONCLUSIONS: This study indicates that both obesity and self-reported past food habit change may be important confounders of diet-breast cancer relationships. The study demonstrates that sensitivity analysis, through stratification, may facilitate interpretation of risk relationships and study results. SN - 1368-9800 UR - https://www.unboundmedicine.com/medline/citation/17381916/Both_food_habit_change_in_the_past_and_obesity_status_may_influence_the_association_between_dietary_factors_and_postmenopausal_breast_cancer_ L2 - https://www.cambridge.org/core/product/identifier/S1368980007246646/type/journal_article DB - PRIME DP - Unbound Medicine ER -