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Electrocardiographic findings at presentation, in relation to in-hospital mortality and 30-day outcome of patients with acute coronary syndromes; the GREECS study.
Int J Cardiol. 2008 Jan 24; 123(3):263-70.IJ

Abstract

BACKGROUND

We sought to evaluate the impact of initial electrocardiographic findings at presentation on in-hospital mortality and 30-day outcome of patients with acute coronary syndromes (ACS).

METHODS

From October 2003 to September 2004, a sample of 6 hospitals located in several urban and rural Greek regions was selected, and almost all survivors 24 h after an admission for ACS were enrolled into the study (2172 patients were included in the study; 76% were men and 24% women). ECG and biochemical indices of myocardial damage were considered in all patients. Electrocardiographic findings at presentation were categorized as ST-elevation (STE), non-STE and non-diagnostic ECG abnormalities.

RESULTS

Of the 2172 patients, 34% had STE, 24% had non-STE and the 32% of them had non-diagnostic ECG abnormalities. After adjusting for age, sex and various other risk factors we observed that patients with STE had 3.3 (95% CI 1.4 to 7.7) higher risk of dying during hospitalization compared to those who had non-diagnostic ECG abnormalities. Furthermore, patients with non-STE had 1.5 (95% CI 0.9 to 2.5) higher risk of having an event (death or re-hospitalization due to CVD) during the first 30-days following discharge as compared to those who had non-diagnostic ECG abnormalities. All patients presented with non-STE ACS had higher 30-day event rates.

CONCLUSION

Patients with STE had higher in-hospital mortality, but lower longer term event rate after ACS in our population, irrespective of age, gender and other characteristics.

Authors+Show Affiliations

First Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17383031

Citation

Pitsavos, Christos, et al. "Electrocardiographic Findings at Presentation, in Relation to In-hospital Mortality and 30-day Outcome of Patients With Acute Coronary Syndromes; the GREECS Study." International Journal of Cardiology, vol. 123, no. 3, 2008, pp. 263-70.
Pitsavos C, Chrysohoou C, Panagiotakos DB, et al. Electrocardiographic findings at presentation, in relation to in-hospital mortality and 30-day outcome of patients with acute coronary syndromes; the GREECS study. Int J Cardiol. 2008;123(3):263-70.
Pitsavos, C., Chrysohoou, C., Panagiotakos, D. B., & Stefanadis, C. (2008). Electrocardiographic findings at presentation, in relation to in-hospital mortality and 30-day outcome of patients with acute coronary syndromes; the GREECS study. International Journal of Cardiology, 123(3), 263-70.
Pitsavos C, et al. Electrocardiographic Findings at Presentation, in Relation to In-hospital Mortality and 30-day Outcome of Patients With Acute Coronary Syndromes; the GREECS Study. Int J Cardiol. 2008 Jan 24;123(3):263-70. PubMed PMID: 17383031.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrocardiographic findings at presentation, in relation to in-hospital mortality and 30-day outcome of patients with acute coronary syndromes; the GREECS study. AU - Pitsavos,Christos, AU - Chrysohoou,Christina, AU - Panagiotakos,Demosthenes B, AU - Stefanadis,Clhristodoulos, AU - ,, Y1 - 2007/03/23/ PY - 2006/06/25/received PY - 2006/10/15/revised PY - 2006/12/11/accepted PY - 2007/3/27/pubmed PY - 2008/1/19/medline PY - 2007/3/27/entrez SP - 263 EP - 70 JF - International journal of cardiology JO - Int. J. Cardiol. VL - 123 IS - 3 N2 - BACKGROUND: We sought to evaluate the impact of initial electrocardiographic findings at presentation on in-hospital mortality and 30-day outcome of patients with acute coronary syndromes (ACS). METHODS: From October 2003 to September 2004, a sample of 6 hospitals located in several urban and rural Greek regions was selected, and almost all survivors 24 h after an admission for ACS were enrolled into the study (2172 patients were included in the study; 76% were men and 24% women). ECG and biochemical indices of myocardial damage were considered in all patients. Electrocardiographic findings at presentation were categorized as ST-elevation (STE), non-STE and non-diagnostic ECG abnormalities. RESULTS: Of the 2172 patients, 34% had STE, 24% had non-STE and the 32% of them had non-diagnostic ECG abnormalities. After adjusting for age, sex and various other risk factors we observed that patients with STE had 3.3 (95% CI 1.4 to 7.7) higher risk of dying during hospitalization compared to those who had non-diagnostic ECG abnormalities. Furthermore, patients with non-STE had 1.5 (95% CI 0.9 to 2.5) higher risk of having an event (death or re-hospitalization due to CVD) during the first 30-days following discharge as compared to those who had non-diagnostic ECG abnormalities. All patients presented with non-STE ACS had higher 30-day event rates. CONCLUSION: Patients with STE had higher in-hospital mortality, but lower longer term event rate after ACS in our population, irrespective of age, gender and other characteristics. SN - 1874-1754 UR - https://www.unboundmedicine.com/medline/citation/17383031/Electrocardiographic_findings_at_presentation_in_relation_to_in_hospital_mortality_and_30_day_outcome_of_patients_with_acute_coronary_syndromes L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-5273(07)00294-X DB - PRIME DP - Unbound Medicine ER -