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Improved health-related quality of life and functional status after surgical ventricular restoration.
Ann Thorac Surg. 2007 Apr; 83(4):1381-7.AT

Abstract

BACKGROUND

Surgical ventricular restoration (SVR) has been shown to improve hemodynamics and survival among patients with coronary artery disease, left ventricular aneurysm, and heart failure. The aim of this study was to investigate functional status and health-related quality of life after SVR.

METHODS

Over a period of 2 years beginning in March 2003, 23 patients with left ventricular aneurysm and depressed left ventricular function were included in a prospective study. Functional status and quality of life was analyzed preoperatively, 6 months postoperatively, and at late follow-up by assessment of New York Heart Association (NYHA) functional class, 6-minute walk test, and the Medical Outcome Study 36-Item Short Form.

RESULTS

There was no early mortality. Before surgery, 17 patients (74%) were in NYHA class III to IV; and 6 months after SVR, 20 patients (87%) were in NYHA class I to II (p < 0.001). At late follow-up, (mean, 22 months postoperatively), all patients alive (n = 20) were in NYHA class I to II. Mean 6-minute walk distance increased by 41 meters (p = 0.06) at 6 months postoperatively and by 57 meters (p = 0.03) at late follow-up. Quality of life, assessed by the physical component summary score of the Medical Outcome Study 36-Item Short Form, improved significantly (p = 0.04) at 6 months postoperatively. A significant and clinically relevant improvement in both physical aspects (+25%, p < 0.001) and mental aspects (+37%, p = 0.003) of quality of life was found at late follow-up.

CONCLUSIONS

Functional status and quality of life improved 6 months after SVR, and the improvement was sustained at late follow-up almost 2 years after surgery.

Authors+Show Affiliations

Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden. ulrik.sartipy@karolinska.seNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17383343

Citation

Sartipy, Ulrik, et al. "Improved Health-related Quality of Life and Functional Status After Surgical Ventricular Restoration." The Annals of Thoracic Surgery, vol. 83, no. 4, 2007, pp. 1381-7.
Sartipy U, Albåge A, Lindblom D. Improved health-related quality of life and functional status after surgical ventricular restoration. Ann Thorac Surg. 2007;83(4):1381-7.
Sartipy, U., Albåge, A., & Lindblom, D. (2007). Improved health-related quality of life and functional status after surgical ventricular restoration. The Annals of Thoracic Surgery, 83(4), 1381-7.
Sartipy U, Albåge A, Lindblom D. Improved Health-related Quality of Life and Functional Status After Surgical Ventricular Restoration. Ann Thorac Surg. 2007;83(4):1381-7. PubMed PMID: 17383343.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Improved health-related quality of life and functional status after surgical ventricular restoration. AU - Sartipy,Ulrik, AU - Albåge,Anders, AU - Lindblom,Dan, PY - 2006/09/18/received PY - 2006/11/09/revised PY - 2006/11/13/accepted PY - 2007/3/27/pubmed PY - 2007/4/14/medline PY - 2007/3/27/entrez SP - 1381 EP - 7 JF - The Annals of thoracic surgery JO - Ann Thorac Surg VL - 83 IS - 4 N2 - BACKGROUND: Surgical ventricular restoration (SVR) has been shown to improve hemodynamics and survival among patients with coronary artery disease, left ventricular aneurysm, and heart failure. The aim of this study was to investigate functional status and health-related quality of life after SVR. METHODS: Over a period of 2 years beginning in March 2003, 23 patients with left ventricular aneurysm and depressed left ventricular function were included in a prospective study. Functional status and quality of life was analyzed preoperatively, 6 months postoperatively, and at late follow-up by assessment of New York Heart Association (NYHA) functional class, 6-minute walk test, and the Medical Outcome Study 36-Item Short Form. RESULTS: There was no early mortality. Before surgery, 17 patients (74%) were in NYHA class III to IV; and 6 months after SVR, 20 patients (87%) were in NYHA class I to II (p < 0.001). At late follow-up, (mean, 22 months postoperatively), all patients alive (n = 20) were in NYHA class I to II. Mean 6-minute walk distance increased by 41 meters (p = 0.06) at 6 months postoperatively and by 57 meters (p = 0.03) at late follow-up. Quality of life, assessed by the physical component summary score of the Medical Outcome Study 36-Item Short Form, improved significantly (p = 0.04) at 6 months postoperatively. A significant and clinically relevant improvement in both physical aspects (+25%, p < 0.001) and mental aspects (+37%, p = 0.003) of quality of life was found at late follow-up. CONCLUSIONS: Functional status and quality of life improved 6 months after SVR, and the improvement was sustained at late follow-up almost 2 years after surgery. SN - 1552-6259 UR - https://www.unboundmedicine.com/medline/citation/17383343/Improved_health_related_quality_of_life_and_functional_status_after_surgical_ventricular_restoration_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-4975(06)02284-3 DB - PRIME DP - Unbound Medicine ER -