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The relationship between influenza vaccination and outpatient visits for upper respiratory infection by the elderly in Taiwan.
Value Health. 2007 Mar-Apr; 10(2):117-27.VH

Abstract

OBJECTIVE

To evaluate the effect of influenza vaccination on the reduction of the risk of outpatient visits for upper respiratory infection (URI) among the elderly in Taiwan.

METHODS

The data for this observational study, consisting of 1729 people aged 65 years or older, were drawn from Taiwan's 2001 National Health Interview Survey. This survey data was then linked with National Health Insurance claim data for December 2001 to November 2002. Survival analysis of Cox proportional hazards model was performed to examine the risk of URI outpatient visits in elderly people vaccinated with the influenza vaccine and those not vaccinated during a year-long study period since the influenza season began. To adjust for potential self-selection bias, we used propensity score method to categorize individuals into two groups, based on the predicted probability of being vaccinated from a logistic regression of spatial random effect. Propensity score group 1 (PSG 1) were those with a predicted probability of being vaccinated lower than 0.5, and PSG 2 were those with a predicted probability of being vaccinated of 0.5 or higher.

RESULTS

The overall vaccination rate was 50%. Logistic regression showed the probability of being vaccinated was related to the number of outpatient visits for URI before the influenza season began (odds ratio (OR) 1.07; 95% confidence interval (CI) 1.04-1.10). Our first survival analysis showed that being vaccinated significantly reduced the risk of URI outpatient visits in PSG 2 during the 1-year study period (hazard ratio 0.89; 95% CI 0.81-0.97). Separate survival analysis showed that being vaccinated reduced the risk of URI outpatient visits for both PSG groups during the first 3 months of the study period.

CONCLUSION

Being vaccinated could reduce the risk of outpatient visits for URI among the elderly during the influenza season.

Authors+Show Affiliations

National Yang-Ming University, Taipei, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17391420

Citation

Tsai, Yi-Wen, et al. "The Relationship Between Influenza Vaccination and Outpatient Visits for Upper Respiratory Infection By the Elderly in Taiwan." Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research, vol. 10, no. 2, 2007, pp. 117-27.
Tsai YW, Huang WF, Wen YW, et al. The relationship between influenza vaccination and outpatient visits for upper respiratory infection by the elderly in Taiwan. Value Health. 2007;10(2):117-27.
Tsai, Y. W., Huang, W. F., Wen, Y. W., & Chen, P. F. (2007). The relationship between influenza vaccination and outpatient visits for upper respiratory infection by the elderly in Taiwan. Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research, 10(2), 117-27.
Tsai YW, et al. The Relationship Between Influenza Vaccination and Outpatient Visits for Upper Respiratory Infection By the Elderly in Taiwan. Value Health. 2007 Mar-Apr;10(2):117-27. PubMed PMID: 17391420.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The relationship between influenza vaccination and outpatient visits for upper respiratory infection by the elderly in Taiwan. AU - Tsai,Yi-Wen, AU - Huang,Weng-Foung, AU - Wen,Yu-Wen, AU - Chen,Pei-Fen, PY - 2007/3/30/pubmed PY - 2007/5/26/medline PY - 2007/3/30/entrez SP - 117 EP - 27 JF - Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research JO - Value Health VL - 10 IS - 2 N2 - OBJECTIVE: To evaluate the effect of influenza vaccination on the reduction of the risk of outpatient visits for upper respiratory infection (URI) among the elderly in Taiwan. METHODS: The data for this observational study, consisting of 1729 people aged 65 years or older, were drawn from Taiwan's 2001 National Health Interview Survey. This survey data was then linked with National Health Insurance claim data for December 2001 to November 2002. Survival analysis of Cox proportional hazards model was performed to examine the risk of URI outpatient visits in elderly people vaccinated with the influenza vaccine and those not vaccinated during a year-long study period since the influenza season began. To adjust for potential self-selection bias, we used propensity score method to categorize individuals into two groups, based on the predicted probability of being vaccinated from a logistic regression of spatial random effect. Propensity score group 1 (PSG 1) were those with a predicted probability of being vaccinated lower than 0.5, and PSG 2 were those with a predicted probability of being vaccinated of 0.5 or higher. RESULTS: The overall vaccination rate was 50%. Logistic regression showed the probability of being vaccinated was related to the number of outpatient visits for URI before the influenza season began (odds ratio (OR) 1.07; 95% confidence interval (CI) 1.04-1.10). Our first survival analysis showed that being vaccinated significantly reduced the risk of URI outpatient visits in PSG 2 during the 1-year study period (hazard ratio 0.89; 95% CI 0.81-0.97). Separate survival analysis showed that being vaccinated reduced the risk of URI outpatient visits for both PSG groups during the first 3 months of the study period. CONCLUSION: Being vaccinated could reduce the risk of outpatient visits for URI among the elderly during the influenza season. SN - 1098-3015 UR - https://www.unboundmedicine.com/medline/citation/17391420/The_relationship_between_influenza_vaccination_and_outpatient_visits_for_upper_respiratory_infection_by_the_elderly_in_Taiwan_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1098-3015(10)60459-7 DB - PRIME DP - Unbound Medicine ER -