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Tea and lycopene protect against prostate cancer.
Asia Pac J Clin Nutr 2007; 16 Suppl 1:453-7AP

Abstract

Prostate cancer is the most common male cancer in developed countries and is increasing in the developing world. Its long latency and geographical variation suggest the possibility of prevention or postponement of onset by dietary modification. To investigate the possible joint effect of lycopene and green tea on prostate cancer risk, a case-control study was conducted in Hangzhou, China, with 130 prostate cancer patients and 274 hospital controls. Information on tea and dietary intakes, and possible confounders was collected using a structured questionnaire. The risk of prostate cancer for the intake of tea and lycopene and their joint effect were assessed using multivariate logistic regression models. Prostate cancer risk was reduced with increased consumption of green tea. The protective effect of green tea was significant (odds ratio 0.14, 95% CI: 0.06-0.35) for the highest quartile relative to the lowest after adjusting for total vegetables and fruits intakes and other potential confounding factors. Intakes of vegetables and fruits rich in lycopene were also inversely associated with prostate cancer risk (odds ratio 0.18, 95% CI 0.08-0.39). Interaction analysis showed that the protective effect from tea and lycopene consumption was synergistic (p<0.01). This study suggests that habitual drinking tea and intakes of vegetables and fruits rich in lycopene could lead to a reduced risk of prostate cancer in Chinese men. Together they have a stronger preventive effect than either component taken separately. This is the first epidemiological study to investigate the joint effect between tea drinking and lycopene intake.

Authors+Show Affiliations

School of Public Health, Curtin University of Technology, GPO Box U 1987, Perth, WA 6845, Australia. L.Jian@exchange.curtin.edu.auNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17392149

Citation

Jian, Le, et al. "Tea and Lycopene Protect Against Prostate Cancer." Asia Pacific Journal of Clinical Nutrition, vol. 16 Suppl 1, 2007, pp. 453-7.
Jian L, Lee AH, Binns CW. Tea and lycopene protect against prostate cancer. Asia Pac J Clin Nutr. 2007;16 Suppl 1:453-7.
Jian, L., Lee, A. H., & Binns, C. W. (2007). Tea and lycopene protect against prostate cancer. Asia Pacific Journal of Clinical Nutrition, 16 Suppl 1, pp. 453-7.
Jian L, Lee AH, Binns CW. Tea and Lycopene Protect Against Prostate Cancer. Asia Pac J Clin Nutr. 2007;16 Suppl 1:453-7. PubMed PMID: 17392149.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tea and lycopene protect against prostate cancer. AU - Jian,Le, AU - Lee,Andy H, AU - Binns,Colin W, PY - 2007/3/30/pubmed PY - 2007/6/15/medline PY - 2007/3/30/entrez SP - 453 EP - 7 JF - Asia Pacific journal of clinical nutrition JO - Asia Pac J Clin Nutr VL - 16 Suppl 1 N2 - Prostate cancer is the most common male cancer in developed countries and is increasing in the developing world. Its long latency and geographical variation suggest the possibility of prevention or postponement of onset by dietary modification. To investigate the possible joint effect of lycopene and green tea on prostate cancer risk, a case-control study was conducted in Hangzhou, China, with 130 prostate cancer patients and 274 hospital controls. Information on tea and dietary intakes, and possible confounders was collected using a structured questionnaire. The risk of prostate cancer for the intake of tea and lycopene and their joint effect were assessed using multivariate logistic regression models. Prostate cancer risk was reduced with increased consumption of green tea. The protective effect of green tea was significant (odds ratio 0.14, 95% CI: 0.06-0.35) for the highest quartile relative to the lowest after adjusting for total vegetables and fruits intakes and other potential confounding factors. Intakes of vegetables and fruits rich in lycopene were also inversely associated with prostate cancer risk (odds ratio 0.18, 95% CI 0.08-0.39). Interaction analysis showed that the protective effect from tea and lycopene consumption was synergistic (p<0.01). This study suggests that habitual drinking tea and intakes of vegetables and fruits rich in lycopene could lead to a reduced risk of prostate cancer in Chinese men. Together they have a stronger preventive effect than either component taken separately. This is the first epidemiological study to investigate the joint effect between tea drinking and lycopene intake. SN - 0964-7058 UR - https://www.unboundmedicine.com/medline/citation/17392149/Tea_and_lycopene_protect_against_prostate_cancer_ L2 - http://apjcn.nhri.org.tw/server/APJCN/16 Suppl 1//453.pdf DB - PRIME DP - Unbound Medicine ER -