Tags

Type your tag names separated by a space and hit enter

Antinociceptive and antipyretic activities of the Zizyphus oxyphylla Edgew. leaves.
Phytother Res. 2007 Jul; 21(7):693-5.PR

Abstract

A methanol extract of Zizyphus oxyphylla Edgew leaves has been investigated for its analgesic and antipyretic activities in Adult Wistar and Swiss albino mice of either sex at 50, 100 and 200 mg/kg orally. The extract demonstrated marked antipyretic activity against Brewer's yeast-induced pyrexia in rats. The extract demonstrated significant peripheral analgesic effect in the acetic acid-induced writhing test in mice. The phytochemical tests revealed that the extract contained alkaloids, anthraquinones, flavonoids, glycosides, phenols, resins, saponins and tannins using standard procedures. In conclusion, the present study suggests that the methanol extract of Zizyphus oxyphylla Edgew leaves possesses potent antipyretic and antinociceptive activities and thus validates its use in the treatment of pain and fever.

Authors+Show Affiliations

Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan. nisaruma@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17397130

Citation

Nisar, M, et al. "Antinociceptive and Antipyretic Activities of the Zizyphus Oxyphylla Edgew. Leaves." Phytotherapy Research : PTR, vol. 21, no. 7, 2007, pp. 693-5.
Nisar M, Adzu B, Inamullah K, et al. Antinociceptive and antipyretic activities of the Zizyphus oxyphylla Edgew. leaves. Phytother Res. 2007;21(7):693-5.
Nisar, M., Adzu, B., Inamullah, K., Bashir, A., Ihsan, A., & Gilani, A. H. (2007). Antinociceptive and antipyretic activities of the Zizyphus oxyphylla Edgew. leaves. Phytotherapy Research : PTR, 21(7), 693-5.
Nisar M, et al. Antinociceptive and Antipyretic Activities of the Zizyphus Oxyphylla Edgew. Leaves. Phytother Res. 2007;21(7):693-5. PubMed PMID: 17397130.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antinociceptive and antipyretic activities of the Zizyphus oxyphylla Edgew. leaves. AU - Nisar,M, AU - Adzu,B, AU - Inamullah,K, AU - Bashir,A, AU - Ihsan,A, AU - Gilani,A H, PY - 2007/4/3/pubmed PY - 2007/8/30/medline PY - 2007/4/3/entrez SP - 693 EP - 5 JF - Phytotherapy research : PTR JO - Phytother Res VL - 21 IS - 7 N2 - A methanol extract of Zizyphus oxyphylla Edgew leaves has been investigated for its analgesic and antipyretic activities in Adult Wistar and Swiss albino mice of either sex at 50, 100 and 200 mg/kg orally. The extract demonstrated marked antipyretic activity against Brewer's yeast-induced pyrexia in rats. The extract demonstrated significant peripheral analgesic effect in the acetic acid-induced writhing test in mice. The phytochemical tests revealed that the extract contained alkaloids, anthraquinones, flavonoids, glycosides, phenols, resins, saponins and tannins using standard procedures. In conclusion, the present study suggests that the methanol extract of Zizyphus oxyphylla Edgew leaves possesses potent antipyretic and antinociceptive activities and thus validates its use in the treatment of pain and fever. SN - 0951-418X UR - https://www.unboundmedicine.com/medline/citation/17397130/Antinociceptive_and_antipyretic_activities_of_the_Zizyphus_oxyphylla_Edgew__leaves_ L2 - https://doi.org/10.1002/ptr.2139 DB - PRIME DP - Unbound Medicine ER -