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Long-term effect of optic edge design in a silicone intraocular lens on posterior capsule opacification.
Am J Ophthalmol. 2007 Jun; 143(6):913-919.AJ

Abstract

PURPOSE

To compare the posterior capsule opacification (PCO) inhibiting effect of the round anterior and sharp posterior optic edge profile of the Clariflex silicone intraocular lens (IOL) [AMO Inc, Santa Ana, California, USA] with that of the double-round edge profile of the SI40 (Phacoflex; AMO Inc, Santa Ana, California, USA) silicone IOL over a period of three years.

DESIGN

Prospective, randomized, double-masked, bilateral clinical trial.

METHODS

The study took place at the Department of Ophthalmology, Medical University of Vienna, Austria. Fifty-two patients with age-related cataracts (104 eyes) were included in the study. Each patient received an SI40 IOL (round edges) in one eye and a Clariflex IOL with OptiEdge (sharp posterior optic edge) in the other eye. Follow-up examinations were at one week, one month, six months, and one, two, and three years. Digital retroillumination images were taken of each eye. The amount of PCO was subjectively assessed with the slit-lamp and objectively assessed by automated image analysis software (the computer program Automated Quantification of After-Cataract [AQUA]; Vienna, Austria) one, two, and three years after surgery.

RESULTS

The Clariflex lens showed markedly less PCO at one, two, and three years after surgery. The mean AQUA PCO score was 1.39 for the SI40 and 0.56 for the Clariflex lens after one year, estimated at 1.64 and 0.57 after two years, and at 2.04 and 0.64, respectively, after three years (scale zero to 10; P < .001). The Nd:YAG laser capsulotomy rate was far higher in the SI40 group (Five cases vs one case at three years).

CONCLUSIONS

The sharp posterior optic edge profile of the Clariflex silicone IOL led to marked and consistently less PCO than the round-edged SI40 IOL one, two, and three years after surgery.

Authors+Show Affiliations

Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17399674

Citation

Buehl, Wolf, et al. "Long-term Effect of Optic Edge Design in a Silicone Intraocular Lens On Posterior Capsule Opacification." American Journal of Ophthalmology, vol. 143, no. 6, 2007, pp. 913-919.
Buehl W, Menapace R, Findl O, et al. Long-term effect of optic edge design in a silicone intraocular lens on posterior capsule opacification. Am J Ophthalmol. 2007;143(6):913-919.
Buehl, W., Menapace, R., Findl, O., Neumayer, T., Bolz, M., & Prinz, A. (2007). Long-term effect of optic edge design in a silicone intraocular lens on posterior capsule opacification. American Journal of Ophthalmology, 143(6), 913-919.
Buehl W, et al. Long-term Effect of Optic Edge Design in a Silicone Intraocular Lens On Posterior Capsule Opacification. Am J Ophthalmol. 2007;143(6):913-919. PubMed PMID: 17399674.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term effect of optic edge design in a silicone intraocular lens on posterior capsule opacification. AU - Buehl,Wolf, AU - Menapace,Rupert, AU - Findl,Oliver, AU - Neumayer,Thomas, AU - Bolz,Matthias, AU - Prinz,Ana, Y1 - 2007/04/02/ PY - 2006/11/30/received PY - 2007/01/31/revised PY - 2007/02/03/accepted PY - 2007/4/3/pubmed PY - 2007/6/29/medline PY - 2007/4/3/entrez SP - 913 EP - 919 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 143 IS - 6 N2 - PURPOSE: To compare the posterior capsule opacification (PCO) inhibiting effect of the round anterior and sharp posterior optic edge profile of the Clariflex silicone intraocular lens (IOL) [AMO Inc, Santa Ana, California, USA] with that of the double-round edge profile of the SI40 (Phacoflex; AMO Inc, Santa Ana, California, USA) silicone IOL over a period of three years. DESIGN: Prospective, randomized, double-masked, bilateral clinical trial. METHODS: The study took place at the Department of Ophthalmology, Medical University of Vienna, Austria. Fifty-two patients with age-related cataracts (104 eyes) were included in the study. Each patient received an SI40 IOL (round edges) in one eye and a Clariflex IOL with OptiEdge (sharp posterior optic edge) in the other eye. Follow-up examinations were at one week, one month, six months, and one, two, and three years. Digital retroillumination images were taken of each eye. The amount of PCO was subjectively assessed with the slit-lamp and objectively assessed by automated image analysis software (the computer program Automated Quantification of After-Cataract [AQUA]; Vienna, Austria) one, two, and three years after surgery. RESULTS: The Clariflex lens showed markedly less PCO at one, two, and three years after surgery. The mean AQUA PCO score was 1.39 for the SI40 and 0.56 for the Clariflex lens after one year, estimated at 1.64 and 0.57 after two years, and at 2.04 and 0.64, respectively, after three years (scale zero to 10; P < .001). The Nd:YAG laser capsulotomy rate was far higher in the SI40 group (Five cases vs one case at three years). CONCLUSIONS: The sharp posterior optic edge profile of the Clariflex silicone IOL led to marked and consistently less PCO than the round-edged SI40 IOL one, two, and three years after surgery. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/17399674/Long_term_effect_of_optic_edge_design_in_a_silicone_intraocular_lens_on_posterior_capsule_opacification_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(07)00183-3 DB - PRIME DP - Unbound Medicine ER -