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Imported melioidosis with an isolated cutaneous presentation in a 90-year-old traveller from Bangladesh.
Bull Soc Pathol Exot. 2007 Feb; 100(1):22-5.BS

Abstract

Melioidosis is a tropical disease caused by infection with the bacterium Burkholderia pseudomallei. Most cases present as an acute febrile illness with severe pneumonia and sepsis. Sub-acute and late onset disease can also occur Melioidosis has been diagnosed among travellers who contracted the disease while staying in endemic areas during the rainy season. We report a case of travel-associated B. pseudomallei cutaneous infection in a febrile 90-year-old woman with diabetes mellitus, with early stage manifestations of an isolated inoculation lesion. A 32 weeks' treatment with oral amoxicillin-clavulanate and doxycycline combination regimen led to resolution of the lesion and lack of relapse over fifteen months of follow-up. Melioidosis should be considered in the differential diagnosis of unusual subacute cutaneous lesions in a febrile patients returning from endemic areas, as successful management largely depends on early diagnosis and specific long-term suppressive antimicrobial therapy at an early stage of the course of the disease.

Authors+Show Affiliations

Service de dermatologie, Centre hospitalier universitaire Erasme, Bruxelles, B-1070 Belgique. kezzedin@ulb.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17402688

Citation

Ezzedine, K, et al. "Imported Melioidosis With an Isolated Cutaneous Presentation in a 90-year-old Traveller From Bangladesh." Bulletin De La Societe De Pathologie Exotique (1990), vol. 100, no. 1, 2007, pp. 22-5.
Ezzedine K, Malvy D, Steels E, et al. Imported melioidosis with an isolated cutaneous presentation in a 90-year-old traveller from Bangladesh. Bull Soc Pathol Exot. 2007;100(1):22-5.
Ezzedine, K., Malvy, D., Steels, E., De Dobbeeler, G., Struelens, M., Jacobs, F., & Heenen, M. (2007). Imported melioidosis with an isolated cutaneous presentation in a 90-year-old traveller from Bangladesh. Bulletin De La Societe De Pathologie Exotique (1990), 100(1), 22-5.
Ezzedine K, et al. Imported Melioidosis With an Isolated Cutaneous Presentation in a 90-year-old Traveller From Bangladesh. Bull Soc Pathol Exot. 2007;100(1):22-5. PubMed PMID: 17402688.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Imported melioidosis with an isolated cutaneous presentation in a 90-year-old traveller from Bangladesh. AU - Ezzedine,K, AU - Malvy,D, AU - Steels,E, AU - De Dobbeeler,G, AU - Struelens,M, AU - Jacobs,F, AU - Heenen,M, PY - 2007/4/4/pubmed PY - 2007/5/4/medline PY - 2007/4/4/entrez SP - 22 EP - 5 JF - Bulletin de la Societe de pathologie exotique (1990) JO - Bull Soc Pathol Exot VL - 100 IS - 1 N2 - Melioidosis is a tropical disease caused by infection with the bacterium Burkholderia pseudomallei. Most cases present as an acute febrile illness with severe pneumonia and sepsis. Sub-acute and late onset disease can also occur Melioidosis has been diagnosed among travellers who contracted the disease while staying in endemic areas during the rainy season. We report a case of travel-associated B. pseudomallei cutaneous infection in a febrile 90-year-old woman with diabetes mellitus, with early stage manifestations of an isolated inoculation lesion. A 32 weeks' treatment with oral amoxicillin-clavulanate and doxycycline combination regimen led to resolution of the lesion and lack of relapse over fifteen months of follow-up. Melioidosis should be considered in the differential diagnosis of unusual subacute cutaneous lesions in a febrile patients returning from endemic areas, as successful management largely depends on early diagnosis and specific long-term suppressive antimicrobial therapy at an early stage of the course of the disease. SN - 0037-9085 UR - https://www.unboundmedicine.com/medline/citation/17402688/Imported_melioidosis_with_an_isolated_cutaneous_presentation_in_a_90_year_old_traveller_from_Bangladesh_ L2 - https://medlineplus.gov/travelershealth.html DB - PRIME DP - Unbound Medicine ER -