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Phyto-oestrogens and risk of prostate cancer in Scottish men.
Br J Nutr. 2007 Aug; 98(2):388-96.BJ

Abstract

A population-based case-control study of diet, inherited susceptibility and prostate cancer was undertaken in the lowlands and central belt of Scotland to investigate the effect of phyto-oestrogen intake and serum concentrations on prostate cancer risk. A total of 433 cases and 483 controls aged 50-74 years were asked to complete a validated FFQ and provide a non-fasting blood sample. Multivariate logistic regression analysis found significant inverse associations with increased serum concentrations of enterolactone (adjusted OR 0.40, 95 % CI 0.22, 0.71] and with the consumption of soy foods (adjusted OR 0.52, 95 % CI 0.30, 0.91). However, no significant associations were observed for isoflavone intake or serum genistein, daidzein and equol. This study supports the hypotheses that soy foods and enterolactone metabolised from dietary lignans protect against prostate cancer in older Scottish men.

Authors+Show Affiliations

Public Health Sciences, University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17403269

Citation

Heald, C L., et al. "Phyto-oestrogens and Risk of Prostate Cancer in Scottish Men." The British Journal of Nutrition, vol. 98, no. 2, 2007, pp. 388-96.
Heald CL, Ritchie MR, Bolton-Smith C, et al. Phyto-oestrogens and risk of prostate cancer in Scottish men. Br J Nutr. 2007;98(2):388-96.
Heald, C. L., Ritchie, M. R., Bolton-Smith, C., Morton, M. S., & Alexander, F. E. (2007). Phyto-oestrogens and risk of prostate cancer in Scottish men. The British Journal of Nutrition, 98(2), 388-96.
Heald CL, et al. Phyto-oestrogens and Risk of Prostate Cancer in Scottish Men. Br J Nutr. 2007;98(2):388-96. PubMed PMID: 17403269.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phyto-oestrogens and risk of prostate cancer in Scottish men. AU - Heald,C L, AU - Ritchie,M R, AU - Bolton-Smith,C, AU - Morton,M S, AU - Alexander,F E, Y1 - 2007/04/03/ PY - 2007/4/4/pubmed PY - 2007/9/18/medline PY - 2007/4/4/entrez SP - 388 EP - 96 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 98 IS - 2 N2 - A population-based case-control study of diet, inherited susceptibility and prostate cancer was undertaken in the lowlands and central belt of Scotland to investigate the effect of phyto-oestrogen intake and serum concentrations on prostate cancer risk. A total of 433 cases and 483 controls aged 50-74 years were asked to complete a validated FFQ and provide a non-fasting blood sample. Multivariate logistic regression analysis found significant inverse associations with increased serum concentrations of enterolactone (adjusted OR 0.40, 95 % CI 0.22, 0.71] and with the consumption of soy foods (adjusted OR 0.52, 95 % CI 0.30, 0.91). However, no significant associations were observed for isoflavone intake or serum genistein, daidzein and equol. This study supports the hypotheses that soy foods and enterolactone metabolised from dietary lignans protect against prostate cancer in older Scottish men. SN - 0007-1145 UR - https://www.unboundmedicine.com/medline/citation/17403269/Phyto_oestrogens_and_risk_of_prostate_cancer_in_Scottish_men_ L2 - https://www.cambridge.org/core/product/identifier/S0007114507700703/type/journal_article DB - PRIME DP - Unbound Medicine ER -